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The map label for this gene is narP [H]

Identifier: 157371727

GI number: 157371727

Start: 3864340

End: 3864972

Strand: Direct

Name: narP [H]

Synonym: Spro_3490

Alternate gene names: 157371727

Gene position: 3864340-3864972 (Clockwise)

Preceding gene: 157371726

Following gene: 157371729

Centisome position: 70.92

GC content: 56.71

Gene sequence:

>633_bases
ATGGTGATGAAGAATTACCGAGTGATGATCGTCGACGACCACCCGCTGATGCGCCGCGGCATTAAACAACTGCTGGGGCT
GGATCCGCTGTTTAGCGTACTGGCCGAAGCCAGCAACGGCAACGAAGCCATTACGCTCGCGCTGCAACACACGCCGGACG
TGATCCTGCTCGATCTGAATATGAAGGGTTTGTCCGGCCTGGACACGCTGAAAGCGCTGCGTAATGAAGGTGTGGATGCC
CGTATTATCGTGCTGACGGTGTCAGACTCACGCAGCGACGTGTACGCGTTGATCGACGCCGGTGCCGACGGCTACCTGCT
GAAAGACAGCGAACCGGAACAGTTGCTGGAACACATTCGCGCGGCGGCGGAAGGAAAGAACGTGATCAGCGACGCGGTCG
CGGACTATCTGTCATCCCGTAGTGAACAACACGACCCCTTTGCCGAACTGACCGAACGCGAGCTGGACGTGCTGCAGGAA
GTGGCGCGTGGCCTTTCCAATAAGCAGGTAGCGGCCCAGTTGCACATTTCTGAAGAGACGGTGAAAGTACATATTCGCAA
TATGCTGCGCAAACTGGATGTACGTTCACGCGTGGCGGCAACGGTGATGTACCTGGAGCACAAGAGTCAATAA

Upstream 100 bases:

>100_bases
CGTGGCGCCAATCGCCACTATTTTATAAGAGTCTGTCCCACTGTGAAGCGTGCTGCACGGCGCGTTTGAGTGGCTTTACT
CGCTACAGGGAGCATATTTC

Downstream 100 bases:

>100_bases
TCTCTCCCCGGCATGCCGGGGAGGCTTTATTCGATGGCGGCAAGCAGCGCCTGATGATGCTGGTGAACCCAGCCCTTGTT
GATCGGTCCCCAGTTTTCCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MVMKNYRVMIVDDHPLMRRGIKQLLGLDPLFSVLAEASNGNEAITLALQHTPDVILLDLNMKGLSGLDTLKALRNEGVDA
RIIVLTVSDSRSDVYALIDAGADGYLLKDSEPEQLLEHIRAAAEGKNVISDAVADYLSSRSEQHDPFAELTERELDVLQE
VARGLSNKQVAAQLHISEETVKVHIRNMLRKLDVRSRVAATVMYLEHKSQ

Sequences:

>Translated_210_residues
MVMKNYRVMIVDDHPLMRRGIKQLLGLDPLFSVLAEASNGNEAITLALQHTPDVILLDLNMKGLSGLDTLKALRNEGVDA
RIIVLTVSDSRSDVYALIDAGADGYLLKDSEPEQLLEHIRAAAEGKNVISDAVADYLSSRSEQHDPFAELTERELDVLQE
VARGLSNKQVAAQLHISEETVKVHIRNMLRKLDVRSRVAATVMYLEHKSQ
>Mature_210_residues
MVMKNYRVMIVDDHPLMRRGIKQLLGLDPLFSVLAEASNGNEAITLALQHTPDVILLDLNMKGLSGLDTLKALRNEGVDA
RIIVLTVSDSRSDVYALIDAGADGYLLKDSEPEQLLEHIRAAAEGKNVISDAVADYLSSRSEQHDPFAELTERELDVLQE
VARGLSNKQVAAQLHISEETVKVHIRNMLRKLDVRSRVAATVMYLEHKSQ

Specific function: Could activate the expression of a formate dehydrogenase operon and could repress the transcription of the fumarate reductase (frdABCD) operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=66.6666666666667, Blast_Score=270, Evalue=6e-74,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=45.771144278607, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788222, Length=204, Percent_Identity=30.8823529411765, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790102, Length=191, Percent_Identity=35.6020942408377, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788712, Length=188, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=27, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788546, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23321; Mature: 23321

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMKNYRVMIVDDHPLMRRGIKQLLGLDPLFSVLAEASNGNEAITLALQHTPDVILLDLN
CCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEC
MKGLSGLDTLKALRNEGVDARIIVLTVSDSRSDVYALIDAGADGYLLKDSEPEQLLEHIR
CCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHHH
AAAEGKNVISDAVADYLSSRSEQHDPFAELTERELDVLQEVARGLSNKQVAAQLHISEET
HHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHH
VKVHIRNMLRKLDVRSRVAATVMYLEHKSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVMKNYRVMIVDDHPLMRRGIKQLLGLDPLFSVLAEASNGNEAITLALQHTPDVILLDLN
CCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEC
MKGLSGLDTLKALRNEGVDARIIVLTVSDSRSDVYALIDAGADGYLLKDSEPEQLLEHIR
CCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHHH
AAAEGKNVISDAVADYLSSRSEQHDPFAELTERELDVLQEVARGLSNKQVAAQLHISEET
HHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHH
VKVHIRNMLRKLDVRSRVAATVMYLEHKSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]