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The map label for this gene is rcsB [H]

Identifier: 157371504

GI number: 157371504

Start: 3605006

End: 3605656

Strand: Direct

Name: rcsB [H]

Synonym: Spro_3267

Alternate gene names: 157371504

Gene position: 3605006-3605656 (Clockwise)

Preceding gene: 157371503

Following gene: 157371507

Centisome position: 66.16

GC content: 49.31

Gene sequence:

>651_bases
ATGAATAACCTGAACGTAATTATTGCTGATGACCATCCTATCGTACTGTTTGGCATCCGGAAGTCACTTGAGCAAATTGA
ATGGGTGAATGTCGTTGGGGAGTTTGAAGACTCAACAGCACTGATCAACAATCTGTCCAAACTGGATGCAAACGTCCTGA
TCACCGACCTTTCGATGCCGGGTGATAAGTATGGCGACGGCATTACGCTGATCAAATACATCAAACGCCATTATCCGCAG
TTGTCGATCATCGTTCTGACCATGAACAACAACCCGGCCATTCTCAGCGCCGTGTTGGATCTGGATATCGAAGGCATAGT
ACTGAAACAGGGTGCGCCAACCGACCTGCCGAAAGCGCTGGCCGCATTGCAAAAAGGCAAGAAATTCACGCCGGAAAGCG
TTTCCAAACTGTTGGAGAGGATCAGCGCCAGTGGTTACGGTGACAAGCGTCTGTCACCAAAAGAGAGCGAAGTACTGCGC
CTGTTCGCCGAAGGTTTCCTGGTGACCGAGATCGCCAAGAAGCTCAATCGCAGCATCAAAACCATCAGTAGCCAGAAGAA
ATCAGCGATGATGAAGTTGGGTGTTGAGAACGATATTGCGCTGCTAAACTACCTCTCTTCCGTCAGCATGGCACCGCTGG
ACAAAGAATAA

Upstream 100 bases:

>100_bases
GAACAGCACATCGCAGACGGTGATGCGCTCAAGATCGAGAATAACATCAGTCAGATTGATTTTTTCGTCAGTAGACTGCT
GCAGCAAGGTAGCCAACAAC

Downstream 100 bases:

>100_bases
AATCCCCGGTAGTTAACAGAGGGCGCGGCATTATGCCGCGCCCTTTTGCTTTCAGGCATCTTCAGACTCAGCGCGCATGC
GGCGAACCTGTTGGCTGTAA

Product: transcriptional regulator RcsB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMPGDKYGDGITLIKYIKRHYPQ
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSKLLERISASGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVSMAPLDKE

Sequences:

>Translated_216_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMPGDKYGDGITLIKYIKRHYPQ
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSKLLERISASGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVSMAPLDKE
>Mature_216_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMPGDKYGDGITLIKYIKRHYPQ
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSKLLERISASGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVSMAPLDKE

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=93.9814814814815, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=27.1844660194175, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=30, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=30.6532663316583, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23751; Mature: 23751

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCC
GDKYGDGITLIKYIKRHYPQLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSKLLERISASGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMMKLGVENDIALLNYLSSVSMAPLDKE
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCC
GDKYGDGITLIKYIKRHYPQLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSKLLERISASGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMMKLGVENDIALLNYLSSVSMAPLDKE
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]