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The map label for this gene is ubiG

Identifier: 157371507

GI number: 157371507

Start: 3611606

End: 3612331

Strand: Direct

Name: ubiG

Synonym: Spro_3270

Alternate gene names: 157371507

Gene position: 3611606-3612331 (Clockwise)

Preceding gene: 157371504

Following gene: 157371508

Centisome position: 66.28

GC content: 57.02

Gene sequence:

>726_bases
ATGAATGCAGAATCATCCAGCCAAGCGCAAAACGTAGACCATCATGAAATCGCCAAGTTCGAGGCCGTGGCCTCACGCTG
GTGGGATTTGGAAGGTGAATTCAAGCCGCTGCACCGTATCAACCCGCTGCGTCTGAACTACATCCTGCAGCGTGCCGGCG
GCATTTTTGACAAAACCGTCCTCGACGTGGGCTGCGGCGGCGGCATTTTGGCGGAAAGCATGGCGCGCGAAGGCGCACAG
GTCACCGGGCTGGACATGGGCGCCGAGCCGCTGCAGGTTGCCCGGTTGCACGCGCTGGAAAGCGGCGTGAATGTGGCTTA
CATCCAGGAAACGGTAGAAAGCCATGCACAGGCCAACCCGCAGCGCTATGACGTAGTGACCTGCATGGAAATGCTGGAGC
ACGTTCCCGACCCGGCCTCGGTGGTACGCGCCTGCGCTCACCTGGTCAAACCGGGTGGCCACGTGTTTTTCTCCACCATT
AACCGCAATACCAAAGCCTGGCTGATGGCAGTGGTCGGTGCGGAATATATTCTGAAGATGGTGCCACAGGGCACCCATGA
CCATAAGAAGTTCATCCGCCCTTCTGAATTGATTGGCTGGGTTGACGGCACGCCACTGCGCGAAAAGCATATGATCGGCC
TGCATTACAACCCAATCACCGACCATTTCAAGCTTGGCCGCAACGTTGATGTGAACTATATGGTACATACTCAGCACGAA
GGTTGA

Upstream 100 bases:

>100_bases
AAATTGTGCATATATGTGCAGTAAAAATGCATCGGCACAGACGGTGCTGCGCCGGAACATGTATAATCCGCGCAACGAGA
ACCAGGAGCCAAATACGCCC

Downstream 100 bases:

>100_bases
GGCTCCCCGAGTGCACCGGGACTGGCCTGTCAGGCCCGGTGCGCCGATAACATTAAGATAAATACCTAATTCTTCCGCTT
TCGATCAAAATCGTCGTTGT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNAESSSQAQNVDHHEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRAGGIFDKTVLDVGCGGGILAESMAREGAQ
VTGLDMGAEPLQVARLHALESGVNVAYIQETVESHAQANPQRYDVVTCMEMLEHVPDPASVVRACAHLVKPGGHVFFSTI
NRNTKAWLMAVVGAEYILKMVPQGTHDHKKFIRPSELIGWVDGTPLREKHMIGLHYNPITDHFKLGRNVDVNYMVHTQHE
G

Sequences:

>Translated_241_residues
MNAESSSQAQNVDHHEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRAGGIFDKTVLDVGCGGGILAESMAREGAQ
VTGLDMGAEPLQVARLHALESGVNVAYIQETVESHAQANPQRYDVVTCMEMLEHVPDPASVVRACAHLVKPGGHVFFSTI
NRNTKAWLMAVVGAEYILKMVPQGTHDHKKFIRPSELIGWVDGTPLREKHMIGLHYNPITDHFKLGRNVDVNYMVHTQHE
G
>Mature_241_residues
MNAESSSQAQNVDHHEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRAGGIFDKTVLDVGCGGGILAESMAREGAQ
VTGLDMGAEPLQVARLHALESGVNVAYIQETVESHAQANPQRYDVVTCMEMLEHVPDPASVVRACAHLVKPGGHVFFSTI
NRNTKAWLMAVVGAEYILKMVPQGTHDHKKFIRPSELIGWVDGTPLREKHMIGLHYNPITDHFKLGRNVDVNYMVHTQHE
G

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=31.5573770491803, Blast_Score=151, Evalue=4e-37,
Organism=Escherichia coli, GI1788564, Length=240, Percent_Identity=78.75, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=32.6359832635983, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324476, Length=247, Percent_Identity=29.9595141700405, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24585589, Length=237, Percent_Identity=34.5991561181435, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI281365311, Length=214, Percent_Identity=36.9158878504673, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_SERP5 (A8GGX8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479496.1
- ProteinModelPortal:   A8GGX8
- STRING:   A8GGX8
- GeneID:   5606908
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3270
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   SPRO399741:SPRO_3270-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26845; Mature: 26845

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAESSSQAQNVDHHEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRAGGIFDKTV
CCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHH
LDVGCGGGILAESMAREGAQVTGLDMGAEPLQVARLHALESGVNVAYIQETVESHAQANP
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
QRYDVVTCMEMLEHVPDPASVVRACAHLVKPGGHVFFSTINRNTKAWLMAVVGAEYILKM
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
VPQGTHDHKKFIRPSELIGWVDGTPLREKHMIGLHYNPITDHFKLGRNVDVNYMVHTQHE
CCCCCCHHHHHCCHHHHEECCCCCCCCCCCEEEEECCCCCHHHHCCCCCCEEEEEEECCC
G
C
>Mature Secondary Structure
MNAESSSQAQNVDHHEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRAGGIFDKTV
CCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHH
LDVGCGGGILAESMAREGAQVTGLDMGAEPLQVARLHALESGVNVAYIQETVESHAQANP
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
QRYDVVTCMEMLEHVPDPASVVRACAHLVKPGGHVFFSTINRNTKAWLMAVVGAEYILKM
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
VPQGTHDHKKFIRPSELIGWVDGTPLREKHMIGLHYNPITDHFKLGRNVDVNYMVHTQHE
CCCCCCHHHHHCCHHHHEECCCCCCCCCCCEEEEECCCCCHHHHCCCCCCEEEEEEECCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA