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The map label for this gene is hypA [H]

Identifier: 157370675

GI number: 157370675

Start: 2668754

End: 2669098

Strand: Direct

Name: hypA [H]

Synonym: Spro_2435

Alternate gene names: 157370675

Gene position: 2668754-2669098 (Clockwise)

Preceding gene: 157370660

Following gene: 157370676

Centisome position: 48.98

GC content: 53.62

Gene sequence:

>345_bases
ATGCACGAAATAACCTTATGCCAACATGCGATGGAAATAATGCAGCAACAGGCTCGCCAAAATAATGCGCAAAGGATCAC
CGCGGTATGGTTCGAGATTGGCGCATTTTCCTGCGTTGAAGCGGAGTCGCTGCGGTTTTGTTTTGACATGGTGTGCCGCG
ACACGCTGGCCGAAGGCTGCGAACTGCATCTGGCGGAACAGAAAGCGCTGTGTTGGTGCCATGACTGCCAGAGCGATGTC
GAGCTGCTGGTACCGCAGGTGCTGGTCTGTCCGCACTGTACCGGACGAAATCTGCGGGTACAGGCCGACGATGGCTTGCA
AATAAAACGCCTGGAAATTGAATAA

Upstream 100 bases:

>100_bases
TGACGATGACAGTCGGTTCGACAAATATGTCATTGGCGGCTTGGCATCATATTTGCAACGTGAGGGGAATAACGCGTTTA
TCACCATTAATGGAGGCCGA

Downstream 100 bases:

>100_bases
CAGAGGGGAATGAATATGTGCAGTACCTGCGGTTGTGCCCAGGGTGAATTAACCATTGAAGGGGATGTGAAGGTGCCATT
CCGTCCGCAACGCAATGTGC

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MHEITLCQHAMEIMQQQARQNNAQRITAVWFEIGAFSCVEAESLRFCFDMVCRDTLAEGCELHLAEQKALCWCHDCQSDV
ELLVPQVLVCPHCTGRNLRVQADDGLQIKRLEIE

Sequences:

>Translated_114_residues
MHEITLCQHAMEIMQQQARQNNAQRITAVWFEIGAFSCVEAESLRFCFDMVCRDTLAEGCELHLAEQKALCWCHDCQSDV
ELLVPQVLVCPHCTGRNLRVQADDGLQIKRLEIE
>Mature_114_residues
MHEITLCQHAMEIMQQQARQNNAQRITAVWFEIGAFSCVEAESLRFCFDMVCRDTLAEGCELHLAEQKALCWCHDCQSDV
ELLVPQVLVCPHCTGRNLRVQADDGLQIKRLEIE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789081, Length=114, Percent_Identity=60.5263157894737, Blast_Score=148, Evalue=8e-38,
Organism=Escherichia coli, GI1789365, Length=114, Percent_Identity=49.1228070175439, Blast_Score=116, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13062; Mature: 13062

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
12.3 %Cys+Met (Translated Protein)
8.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
12.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEITLCQHAMEIMQQQARQNNAQRITAVWFEIGAFSCVEAESLRFCFDMVCRDTLAEGC
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
ELHLAEQKALCWCHDCQSDVELLVPQVLVCPHCTGRNLRVQADDGLQIKRLEIE
EEEECCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECC
>Mature Secondary Structure
MHEITLCQHAMEIMQQQARQNNAQRITAVWFEIGAFSCVEAESLRFCFDMVCRDTLAEGC
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
ELHLAEQKALCWCHDCQSDVELLVPQVLVCPHCTGRNLRVQADDGLQIKRLEIE
EEEECCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA