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The map label for this gene is yusP [H]

Identifier: 157370526

GI number: 157370526

Start: 2490124

End: 2491611

Strand: Direct

Name: yusP [H]

Synonym: Spro_2286

Alternate gene names: 157370526

Gene position: 2490124-2491611 (Clockwise)

Preceding gene: 157370524

Following gene: 157370529

Centisome position: 45.7

GC content: 58.0

Gene sequence:

>1488_bases
ATGACAAATAACGATGCATCAGCCCCAATCGCTCATCGCCCCTTAATCTTGATTGCCTGCATGTTGGCGATGTTTATGTC
GGCAATAGAAGCGACCATTGTCGCCACGGCGATGCCAACCATTATCGGCGATCTCGGTGGTTTTTCCCTGCTAGGCTGGG
TATTCGCGGTCTATCTATTGGCGCAGGCCATCACTATTCCCATATATGGTCGGCTGGCGGACCTGCTGGGGCGCAAGCGG
GTATTTTTCTTTGGTGCATCGCTGTTTTTACTGGGTTCGGTGCTGTGCGGTTTCTCGCCGAACATGTACTGGCTGATCGG
TTTTCGTCTGCTGCAGGGGTTGGGGGCCGGGGCGATTATGCCAACCGCGACCACCATTATTGGTGATATCTACAGCCCTA
CCGAGCGGCCCAAGGTGATGGGCTATATTTCCAGCGTTTGGGGTGTGTCGGCGATTATTGGACCCTTGCTGGGGGCGTTT
ATCGTCCAGCATTTGCCCTGGGCGTTGGTGTTCTGGGTCAACTTGCCGATCGGTCTGTTGGCGATGTTTTTCCTGGCTCG
TTATCTGCCTTCCCGTCAGCAGGTGCGCGAACACGCGTTGGATCTGGCGGGGACCGCCTGGCTGACGTTGTTTGTTACCG
CGTTGCTGCTGTCACTGCTGCAGGCAGAAAATCTCGGTTGGTGGGTGCTGCCGTTGTTGGCGTTGGCGGCCGTCTCGCTG
ATGTTGCTGATCCGCCAGGAACGACGAGCGCCGGAGCCACTGTTTCCGTTGGCGTTATGGCAAAGCCGGGTGATCGTGGC
CGGCAATATTGGCGGCCTGGTGATTGGCGCGGCGATGATGGGCATCAGCGCCTTTCTGCCGACCTTTATTCAGGGCGTGA
TGGGCGGAACGCCCCTGGAGGCCGGTACCACGCTGGCGCTGATGTCAATTGGCTGGCCGCTGGCCAGTACCTTCAGCGGT
CGACTGATGCTGATGACTTCTTATCGCACCACGGCGCTATTGGGAGCGTTGTTATTACTGGCCGGCGGTCTGATTCTGTT
GTTGTTGCAGCCGACCGGCGGCTTATTGTGGGGTCGGGTGGCGGCGTTTATGGTCGGTGCCGGTATGGGGTTGTGCAACA
CCACGTTTCTGGTTTCGGTGCAGAACGCGGCTCACCACAGCATCCGCGGCATTGCCACCGCCTGCACGGTGTTTACCCGG
ATGATGGGTTCGGCCATTGGTACCGCCATTTTGGGCGCAACGCTGAACATCAACTTGCAGTTTCGTTTGCCGCAAACGAC
CGATCCGGTACAACAACTGATGGAACCGGCTGCGCGTAGCGCGATGACGCCAGAAATACTGGCGGAGATGACGCAGCAAG
TTGCCGCTTCGTTGCATTGGGTGTTTTTGGTTTCTGCACTGTTGTCATTGCTGGCACTGGCGGCGGCGATGCTGATCCCG
GCGCGGCACAGACCACAGGGTGAGGGAGAAGAGGCTGAACAGGCTTAA

Upstream 100 bases:

>100_bases
ATAATCAGTAAAAACAGGGAAATAGACACCGGTAACGGCAAGCTCTAATTCGGCTGGTATAATTTAAGGCAAACAAGAAT
CCACGGTTTGTAATAAAGCT

Downstream 100 bases:

>100_bases
ATAAAAAGGAAAGGGCGCACCGAGCGCCCTGAGCGGAAACTATTGCGAGGTTTTGGTATCCTGACTGGTGCCGGTCTGAG
CCGCGTCACCATTGTCATCG

Product: EmrB/QacA family drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTNNDASAPIAHRPLILIACMLAMFMSAIEATIVATAMPTIIGDLGGFSLLGWVFAVYLLAQAITIPIYGRLADLLGRKR
VFFFGASLFLLGSVLCGFSPNMYWLIGFRLLQGLGAGAIMPTATTIIGDIYSPTERPKVMGYISSVWGVSAIIGPLLGAF
IVQHLPWALVFWVNLPIGLLAMFFLARYLPSRQQVREHALDLAGTAWLTLFVTALLLSLLQAENLGWWVLPLLALAAVSL
MLLIRQERRAPEPLFPLALWQSRVIVAGNIGGLVIGAAMMGISAFLPTFIQGVMGGTPLEAGTTLALMSIGWPLASTFSG
RLMLMTSYRTTALLGALLLLAGGLILLLLQPTGGLLWGRVAAFMVGAGMGLCNTTFLVSVQNAAHHSIRGIATACTVFTR
MMGSAIGTAILGATLNINLQFRLPQTTDPVQQLMEPAARSAMTPEILAEMTQQVAASLHWVFLVSALLSLLALAAAMLIP
ARHRPQGEGEEAEQA

Sequences:

>Translated_495_residues
MTNNDASAPIAHRPLILIACMLAMFMSAIEATIVATAMPTIIGDLGGFSLLGWVFAVYLLAQAITIPIYGRLADLLGRKR
VFFFGASLFLLGSVLCGFSPNMYWLIGFRLLQGLGAGAIMPTATTIIGDIYSPTERPKVMGYISSVWGVSAIIGPLLGAF
IVQHLPWALVFWVNLPIGLLAMFFLARYLPSRQQVREHALDLAGTAWLTLFVTALLLSLLQAENLGWWVLPLLALAAVSL
MLLIRQERRAPEPLFPLALWQSRVIVAGNIGGLVIGAAMMGISAFLPTFIQGVMGGTPLEAGTTLALMSIGWPLASTFSG
RLMLMTSYRTTALLGALLLLAGGLILLLLQPTGGLLWGRVAAFMVGAGMGLCNTTFLVSVQNAAHHSIRGIATACTVFTR
MMGSAIGTAILGATLNINLQFRLPQTTDPVQQLMEPAARSAMTPEILAEMTQQVAASLHWVFLVSALLSLLALAAAMLIP
ARHRPQGEGEEAEQA
>Mature_494_residues
TNNDASAPIAHRPLILIACMLAMFMSAIEATIVATAMPTIIGDLGGFSLLGWVFAVYLLAQAITIPIYGRLADLLGRKRV
FFFGASLFLLGSVLCGFSPNMYWLIGFRLLQGLGAGAIMPTATTIIGDIYSPTERPKVMGYISSVWGVSAIIGPLLGAFI
VQHLPWALVFWVNLPIGLLAMFFLARYLPSRQQVREHALDLAGTAWLTLFVTALLLSLLQAENLGWWVLPLLALAAVSLM
LLIRQERRAPEPLFPLALWQSRVIVAGNIGGLVIGAAMMGISAFLPTFIQGVMGGTPLEAGTTLALMSIGWPLASTFSGR
LMLMTSYRTTALLGALLLLAGGLILLLLQPTGGLLWGRVAAFMVGAGMGLCNTTFLVSVQNAAHHSIRGIATACTVFTRM
MGSAIGTAILGATLNINLQFRLPQTTDPVQQLMEPAARSAMTPEILAEMTQQVAASLHWVFLVSALLSLLALAAAMLIPA
RHRPQGEGEEAEQA

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=317, Percent_Identity=29.3375394321767, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789042, Length=301, Percent_Identity=31.5614617940199, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788710, Length=312, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081983, Length=421, Percent_Identity=28.2660332541568, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788392, Length=297, Percent_Identity=28.956228956229, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790146, Length=193, Percent_Identity=29.5336787564767, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564663, Length=116, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319770, Length=479, Percent_Identity=25.678496868476, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322958, Length=192, Percent_Identity=29.6875, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321663, Length=149, Percent_Identity=30.8724832214765, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323735, Length=166, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324954, Length=386, Percent_Identity=27.4611398963731, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=157, Percent_Identity=29.9363057324841, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52820; Mature: 52689

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNNDASAPIAHRPLILIACMLAMFMSAIEATIVATAMPTIIGDLGGFSLLGWVFAVYLL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH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CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]