Click here to switch to the map view.

The map label for this gene is dtpA [H]

Identifier: 157370174

GI number: 157370174

Start: 2116416

End: 2118026

Strand: Direct

Name: dtpA [H]

Synonym: Spro_1932

Alternate gene names: 157370174

Gene position: 2116416-2118026 (Clockwise)

Preceding gene: 157370173

Following gene: 157370175

Centisome position: 38.84

GC content: 57.73

Gene sequence:

>1611_bases
ATGGAAAGGTGCTGGCGCGGGGTTTTGGCAAGGATTATCACACCGCCGCGCAGGTTGCCGGGCAACGACCCGGCGATAAG
CAGACAGGGATTGATCTATCAAATAATAATGCAGCAGAGGTTCACTTTGACTTCGTCAGATTCCACACCGACGGCGCCAC
AACGCCATGCCATCCCCCCGGGAGCCGGGGCACTGTTCTTTATCCAAATCTTCGCCACGCTGGGTTTTGCCGTGCTGTAC
TCCACGTTGGTACTGTACGCCACCAAGCGTTTGGGCTTCAGCGAAACGAACGCTAATGCCATGATGGGCGTATTCGGGGC
GTTCAACTACGGCTTGCATATGTTCGGCGGCTATCTGGGTGGGCGCTTCCTCAGTAACCGCAACCTGTTCGTACTGGGTA
TGGTGCTGCAGGTGATTGGCTGCGCGTTGATCGCCGTGGCGGGTGTCTGGGGACTTTACTGGGGCCTGGCGATGTTCCTG
ACCGGCAGTGGGCTGAACGTCACCTGCATTAATATGATGTTGACCCAGCGTTTTAAGCCGGACGACGATCGGCGTGAATC
AGCCTTCTTGTGGAACTATGCCGGGATGAACCTGGGGTTCTTTGTCGGTTTTACCGTCGCCGGCTATTTCCAACTGACCG
AAAACTACCGCGCGCTGTTCCTGTTCGCCACGCTGGGCAATGCGGCGGCAATCATCGTCGCCGTCAGCCGTTGGCGCATT
CTGGCCGATCTCAACACACCATTGCATGACGCCAGCCGTGGAGAATATCGCTGGCGCATGCTGGTCGGGTTAGCGGTATT
GGTGGTGTTGGTGCCTATTATCCGCGTGATGCTGACCCACGCCGAGTTCAGCGGTCACTTCGTCATTGGCCTCGGCGTGC
TGATTTTCCTGATGCTGTGCGTGGTCACGTTACGTCATCATCCGCGTGACGAGCGTCGCCGGATGACCGCTTATCTGATC
CTGGCATTGGGGTCACTGGTGTTTTGGTCGCTGTATCAGTTGGCGCCAATGGGGCTGATGCTGTTCTCCGAGCACAACAT
CAATTTGAATGTCTACGGCATTCAGGTGGCACCGCAATGGATCCAGAACATCAATACGTTGGTGATCGTGGTCGGTGGGC
CGCTGATGGCCTGGTGGTTCAATCGCCTGCGCGCCCGTGGCTGCAAAATCGACATTCCCATGCAGTTTTCCGGTTCGTTG
TTTTTTATCGGGTTGGGTATGCTGGTCTTGCCGTTGGGTATCAGCCTGGCCGGCGGTGACGGGCTGGTGGCGTTTAAATG
GATTGCCATCAGTTATGTGCTGCAGAGCATCGGTGAACTGATGATTTCCCCGATCGGCTACGCGATGATCGGCAAACTGG
CCCCCCCGCGCTATCAGGGGGTGATGATGGGCTGCTGGATGATGGTCACCGGCGTCGCTTCGGTATTGGCGGGCTACGTC
TCGGGCCTGATGCCGGAAAACAGCGGAAGTACCCCGGTGTTGACCAACCCCGGTTACAGCGAAGTGTTTAGCGTGCTGGG
CTGGGGAGCCGCAGGTGTCGGCGTGGTGATGCTGATTTTGATCCCGCTGCTGCGCCGCCTAATCAGGCATGACACCCCGG
TCGCAGCCTGA

Upstream 100 bases:

>100_bases
GAACGCTTCAGTATGCGTTAGCTCAATATATCAGCAACAGTGAAGTCTGCAGTGCTGTTATATGCATTAATACTGGATTA
TTAGTCATATGTGTCGCTAA

Downstream 100 bases:

>100_bases
GAGCCCGCCGTATGAACACAGCCCCACTGGTCGGGGCTGTTTTCGTTTTGGGCTTTAACGCTTGCATCTGCCGACGAATC
GCGGAAGTCTGGATGGAAAT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MERCWRGVLARIITPPRRLPGNDPAISRQGLIYQIIMQQRFTLTSSDSTPTAPQRHAIPPGAGALFFIQIFATLGFAVLY
STLVLYATKRLGFSETNANAMMGVFGAFNYGLHMFGGYLGGRFLSNRNLFVLGMVLQVIGCALIAVAGVWGLYWGLAMFL
TGSGLNVTCINMMLTQRFKPDDDRRESAFLWNYAGMNLGFFVGFTVAGYFQLTENYRALFLFATLGNAAAIIVAVSRWRI
LADLNTPLHDASRGEYRWRMLVGLAVLVVLVPIIRVMLTHAEFSGHFVIGLGVLIFLMLCVVTLRHHPRDERRRMTAYLI
LALGSLVFWSLYQLAPMGLMLFSEHNINLNVYGIQVAPQWIQNINTLVIVVGGPLMAWWFNRLRARGCKIDIPMQFSGSL
FFIGLGMLVLPLGISLAGGDGLVAFKWIAISYVLQSIGELMISPIGYAMIGKLAPPRYQGVMMGCWMMVTGVASVLAGYV
SGLMPENSGSTPVLTNPGYSEVFSVLGWGAAGVGVVMLILIPLLRRLIRHDTPVAA

Sequences:

>Translated_536_residues
MERCWRGVLARIITPPRRLPGNDPAISRQGLIYQIIMQQRFTLTSSDSTPTAPQRHAIPPGAGALFFIQIFATLGFAVLY
STLVLYATKRLGFSETNANAMMGVFGAFNYGLHMFGGYLGGRFLSNRNLFVLGMVLQVIGCALIAVAGVWGLYWGLAMFL
TGSGLNVTCINMMLTQRFKPDDDRRESAFLWNYAGMNLGFFVGFTVAGYFQLTENYRALFLFATLGNAAAIIVAVSRWRI
LADLNTPLHDASRGEYRWRMLVGLAVLVVLVPIIRVMLTHAEFSGHFVIGLGVLIFLMLCVVTLRHHPRDERRRMTAYLI
LALGSLVFWSLYQLAPMGLMLFSEHNINLNVYGIQVAPQWIQNINTLVIVVGGPLMAWWFNRLRARGCKIDIPMQFSGSL
FFIGLGMLVLPLGISLAGGDGLVAFKWIAISYVLQSIGELMISPIGYAMIGKLAPPRYQGVMMGCWMMVTGVASVLAGYV
SGLMPENSGSTPVLTNPGYSEVFSVLGWGAAGVGVVMLILIPLLRRLIRHDTPVAA
>Mature_536_residues
MERCWRGVLARIITPPRRLPGNDPAISRQGLIYQIIMQQRFTLTSSDSTPTAPQRHAIPPGAGALFFIQIFATLGFAVLY
STLVLYATKRLGFSETNANAMMGVFGAFNYGLHMFGGYLGGRFLSNRNLFVLGMVLQVIGCALIAVAGVWGLYWGLAMFL
TGSGLNVTCINMMLTQRFKPDDDRRESAFLWNYAGMNLGFFVGFTVAGYFQLTENYRALFLFATLGNAAAIIVAVSRWRI
LADLNTPLHDASRGEYRWRMLVGLAVLVVLVPIIRVMLTHAEFSGHFVIGLGVLIFLMLCVVTLRHHPRDERRRMTAYLI
LALGSLVFWSLYQLAPMGLMLFSEHNINLNVYGIQVAPQWIQNINTLVIVVGGPLMAWWFNRLRARGCKIDIPMQFSGSL
FFIGLGMLVLPLGISLAGGDGLVAFKWIAISYVLQSIGELMISPIGYAMIGKLAPPRYQGVMMGCWMMVTGVASVLAGYV
SGLMPENSGSTPVLTNPGYSEVFSVLGWGAAGVGVVMLILIPLLRRLIRHDTPVAA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=498, Percent_Identity=28.714859437751, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1789911, Length=473, Percent_Identity=27.061310782241, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786927, Length=487, Percent_Identity=24.8459958932238, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1790572, Length=457, Percent_Identity=24.2888402625821, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 58955; Mature: 58955

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERCWRGVLARIITPPRRLPGNDPAISRQGLIYQIIMQQRFTLTSSDSTPTAPQRHAIPP
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCEEECCCCCCCCCCCCCCCC
GAGALFFIQIFATLGFAVLYSTLVLYATKRLGFSETNANAMMGVFGAFNYGLHMFGGYLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GRFLSNRNLFVLGMVLQVIGCALIAVAGVWGLYWGLAMFLTGSGLNVTCINMMLTQRFKP
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
DDDRRESAFLWNYAGMNLGFFVGFTVAGYFQLTENYRALFLFATLGNAAAIIVAVSRWRI
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEHHHHEE
LADLNTPLHDASRGEYRWRMLVGLAVLVVLVPIIRVMLTHAEFSGHFVIGLGVLIFLMLC
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VVTLRHHPRDERRRMTAYLILALGSLVFWSLYQLAPMGLMLFSEHNINLNVYGIQVAPQW
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEEEECHHH
IQNINTLVIVVGGPLMAWWFNRLRARGCKIDIPMQFSGSLFFIGLGMLVLPLGISLAGGD
HCCCCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEECCC
GLVAFKWIAISYVLQSIGELMISPIGYAMIGKLAPPRYQGVMMGCWMMVTGVASVLAGYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGLMPENSGSTPVLTNPGYSEVFSVLGWGAAGVGVVMLILIPLLRRLIRHDTPVAA
HCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERCWRGVLARIITPPRRLPGNDPAISRQGLIYQIIMQQRFTLTSSDSTPTAPQRHAIPP
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCEEECCCCCCCCCCCCCCCC
GAGALFFIQIFATLGFAVLYSTLVLYATKRLGFSETNANAMMGVFGAFNYGLHMFGGYLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GRFLSNRNLFVLGMVLQVIGCALIAVAGVWGLYWGLAMFLTGSGLNVTCINMMLTQRFKP
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
DDDRRESAFLWNYAGMNLGFFVGFTVAGYFQLTENYRALFLFATLGNAAAIIVAVSRWRI
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEHHHHEE
LADLNTPLHDASRGEYRWRMLVGLAVLVVLVPIIRVMLTHAEFSGHFVIGLGVLIFLMLC
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VVTLRHHPRDERRRMTAYLILALGSLVFWSLYQLAPMGLMLFSEHNINLNVYGIQVAPQW
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEEEECHHH
IQNINTLVIVVGGPLMAWWFNRLRARGCKIDIPMQFSGSLFFIGLGMLVLPLGISLAGGD
HCCCCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEECCC
GLVAFKWIAISYVLQSIGELMISPIGYAMIGKLAPPRYQGVMMGCWMMVTGVASVLAGYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGLMPENSGSTPVLTNPGYSEVFSVLGWGAAGVGVVMLILIPLLRRLIRHDTPVAA
HCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA