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The map label for this gene is dapA [H]

Identifier: 157370080

GI number: 157370080

Start: 2022869

End: 2023789

Strand: Reverse

Name: dapA [H]

Synonym: Spro_1838

Alternate gene names: 157370080

Gene position: 2023789-2022869 (Counterclockwise)

Preceding gene: 157370081

Following gene: 157370079

Centisome position: 37.14

GC content: 56.89

Gene sequence:

>921_bases
ATGAGCCATAAAGCCATTAGCTGGAGCGGCGTGTTCCCGGCGGTCAGCACTCAGTTTCGTAGCGATTTCTCTCTGGATCT
CGATGCCACCCATACGGTGATAAAAAACCTGGTCAAAGACGGCGTTTCTGGCCTGGTGGTGTGTGGCACCGTGGGCGAAA
ACACCTCGATGACCGTTCAGGAAAAATTGTCGGTGATTGAAGTGGCACGCGATGCCGCACAAGGCAAAGTACCGGTGATT
GCCGGAATTGCCGAATTCACTACGGCCTTTGCTCGCAATATGGCGCAAGAAGCGCAAAAGGTCGGCGTCGACGGCATCAT
GGTCATGCCTGCGCTGGTCTACTCCGCCAAACCCCATGAAACTGCCGCCCACTTTCGCAGCGTTGCCGCTGCCACCGATC
TGCCGATCATGGTCTACAACAACCCGCCAATTTACAAAAACGATGTGACGCCCGACATCCTGACGTCCTTGGTTGATTGC
GAAAATATCGTGTGCTTCAAAGACTCCTCCGGCGACACCCGCCGCTTTATCGATCTGCGTAACGAAGTGGGCGATCGCTT
TGTGCTGTTCGCCGGGCTTGATGACGTGGTGCTGGAAAGTATCGCCGTCGGTGCCGAAGGCTGGATCTCCGGCATGTCCA
ACGCCTTCCCGCGTGAAGGGGAAACGCTGTTCCGTCTGGCGAAGCAAAAACGCTTTGAGGAAGCCCTGGCGCTGTATAGC
TGGTTTATGCCGTTGCTGCATCTGGACGCTCGTCCGGACCTGGTGCAATGCATCAAGCTGTGTGAAGAGTTGGTCGGCCG
CGGCAGCGCCATTACCCGTCCGCCACGCCTGGCATTACAGGGCGATACCCTGGCAGAAGTCACCGCCGTGGTTAAAAAAG
CGCTGGCAAATCGCCCTGAATTGCCGGACGTCGGCCTGTAA

Upstream 100 bases:

>100_bases
AAAACCGTCAAGCCCCTGCGGACAATACAGGTCAATCTGTGATTGGATTTTACCAATAATTCACCATTGATTAACAAACT
TGGACGACAGGATAAACACT

Downstream 100 bases:

>100_bases
TTGCCACTCTCGCCCGGCCGCCTGCCGGGCCTGAACACCAGCCAACCGGGGGAACCCATGTCCAACGCTTATACCATCCG
TGGTCAACAGTTTATCGGCG

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSHKAISWSGVFPAVSTQFRSDFSLDLDATHTVIKNLVKDGVSGLVVCGTVGENTSMTVQEKLSVIEVARDAAQGKVPVI
AGIAEFTTAFARNMAQEAQKVGVDGIMVMPALVYSAKPHETAAHFRSVAAATDLPIMVYNNPPIYKNDVTPDILTSLVDC
ENIVCFKDSSGDTRRFIDLRNEVGDRFVLFAGLDDVVLESIAVGAEGWISGMSNAFPREGETLFRLAKQKRFEEALALYS
WFMPLLHLDARPDLVQCIKLCEELVGRGSAITRPPRLALQGDTLAEVTAVVKKALANRPELPDVGL

Sequences:

>Translated_306_residues
MSHKAISWSGVFPAVSTQFRSDFSLDLDATHTVIKNLVKDGVSGLVVCGTVGENTSMTVQEKLSVIEVARDAAQGKVPVI
AGIAEFTTAFARNMAQEAQKVGVDGIMVMPALVYSAKPHETAAHFRSVAAATDLPIMVYNNPPIYKNDVTPDILTSLVDC
ENIVCFKDSSGDTRRFIDLRNEVGDRFVLFAGLDDVVLESIAVGAEGWISGMSNAFPREGETLFRLAKQKRFEEALALYS
WFMPLLHLDARPDLVQCIKLCEELVGRGSAITRPPRLALQGDTLAEVTAVVKKALANRPELPDVGL
>Mature_305_residues
SHKAISWSGVFPAVSTQFRSDFSLDLDATHTVIKNLVKDGVSGLVVCGTVGENTSMTVQEKLSVIEVARDAAQGKVPVIA
GIAEFTTAFARNMAQEAQKVGVDGIMVMPALVYSAKPHETAAHFRSVAAATDLPIMVYNNPPIYKNDVTPDILTSLVDCE
NIVCFKDSSGDTRRFIDLRNEVGDRFVLFAGLDDVVLESIAVGAEGWISGMSNAFPREGETLFRLAKQKRFEEALALYSW
FMPLLHLDARPDLVQCIKLCEELVGRGSAITRPPRLALQGDTLAEVTAVVKKALANRPELPDVGL

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=238, Percent_Identity=27.3109243697479, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI87082415, Length=270, Percent_Identity=31.1111111111111, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788823, Length=261, Percent_Identity=30.2681992337165, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786463, Length=266, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789620, Length=211, Percent_Identity=28.436018957346, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33194; Mature: 33062

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHKAISWSGVFPAVSTQFRSDFSLDLDATHTVIKNLVKDGVSGLVVCGTVGENTSMTVQ
CCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
EKLSVIEVARDAAQGKVPVIAGIAEFTTAFARNMAQEAQKVGVDGIMVMPALVYSAKPHE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHH
TAAHFRSVAAATDLPIMVYNNPPIYKNDVTPDILTSLVDCENIVCFKDSSGDTRRFIDLR
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
NEVGDRFVLFAGLDDVVLESIAVGAEGWISGMSNAFPREGETLFRLAKQKRFEEALALYS
HHCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
WFMPLLHLDARPDLVQCIKLCEELVGRGSAITRPPRLALQGDTLAEVTAVVKKALANRPE
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCC
LPDVGL
CCCCCC
>Mature Secondary Structure 
SHKAISWSGVFPAVSTQFRSDFSLDLDATHTVIKNLVKDGVSGLVVCGTVGENTSMTVQ
CCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
EKLSVIEVARDAAQGKVPVIAGIAEFTTAFARNMAQEAQKVGVDGIMVMPALVYSAKPHE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHH
TAAHFRSVAAATDLPIMVYNNPPIYKNDVTPDILTSLVDCENIVCFKDSSGDTRRFIDLR
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
NEVGDRFVLFAGLDDVVLESIAVGAEGWISGMSNAFPREGETLFRLAKQKRFEEALALYS
HHCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
WFMPLLHLDARPDLVQCIKLCEELVGRGSAITRPPRLALQGDTLAEVTAVVKKALANRPE
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCC
LPDVGL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA