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The map label for this gene is aldH [H]

Identifier: 157370079

GI number: 157370079

Start: 2021201

End: 2022811

Strand: Reverse

Name: aldH [H]

Synonym: Spro_1837

Alternate gene names: 157370079

Gene position: 2022811-2021201 (Counterclockwise)

Preceding gene: 157370080

Following gene: 157370078

Centisome position: 37.12

GC content: 61.58

Gene sequence:

>1611_bases
ATGTCCAACGCTTATACCATCCGTGGTCAACAGTTTATCGGCGGTCAACGCCGTGCCAGCGGTGAGGCCGAACTGGTCAG
CCTGCGTGCCGATAACGGCCAGCCAACCGGCCACCGTTTTTTCTCGGCCAGCATCGCAGAAACCGCCGCCGCCGCCGATG
CCGCCGCACAGGCGTTCACCGCCTATTCACAACTCAGTGCCGAACGGCGGGCTGACTTCCTTGAGGCGATTGCCGGGCAG
TTGGATGCACTGGATGAGGAATTTTTTAACTACGCCATGCAGGAGACCGCTCTACCATTAGCTCGTCTGAGCGGTGAACG
CGCCAGAACCAGTGGCCAGATGCGGTTATTTGCCAGCCTGTTGCGCCGTGGTGATGTGCACGGCGTACGCATAGACTGCG
CCTTGCCGCAGCGCACACCGCTGCCGCGTCCGGATCTGCGCCAATACCGCACGGCGCTCGGGCCGGTGGCAGTGTTTGGT
GCCAGCAATTTCCCGTTGGCCTTCTCTACCGCAGGCGGTGATACCGCCGCTGCCCTGGCCGCAGGCTGCCCGGTGGTATT
CAAGGCGCACAGCGGCCACATGATCACCGCCGAGCTGACCGCACAGGCGATTGAACGGGCCAGAGAGCAGCAACAGATCC
CGGCCGGGGTATTCAACATGATTTACGGCGACCGCATCGGCGCGGAACTGGTACAGCACCCGGCCATTCAGGCGGTGGGC
TTTACCGGTTCGCTGCGCGGCGGCAGAGCCTTGTTCGATCTGGCCATGCGCCGTCCGCAGCCGATCCCGGTCTTTGCCGA
GATGTCGAGCATCAACCCGCTGATCATCATGCCGCAGGCCTTAGCCCAACGTGGGCAGCAGATCGCACGCGAGCTGGTGG
CCTCATTCACTCTGGGTTGCGGCCAGTTCTGTACCAAGCCGGGGCTGATCATCGGCCAACGCAGTGAAGCATTCAGTCAA
TTTATGGGTGAATTAACCGAGCAGGTGAACGCCGCCGCTCCGCAACCGATGCTCAATATCGGCACGCTGGCACATTACCG
CAGCGGATTGGCAGCACTGGATCAGCACGACGGCATTCGCCATCTGGCCGGCAGCCGCGAGGCCCCCCCTTTTTTAGCCG
CACCGCAACTGTATCAGGCCGATATCGGCTTACTGCTCAGCGGCAATCCCTTGCTGCAGGAGGAAGTGTTTGGCCCGGTA
GCCATTCTGGTGACGGTGGAAAATCATCAGCAACTGACCGCCGCACTGGAAAGCTTGCAAGGCCAACTGACCGCCACGCT
GCTGACCGACCCAGAGGATCTGGCCGATGCCGAACCGCTGGCGCAGTTGCTGACCCGCAAGGCCGGTCGGGTGCTGTTCA
ATGGCTACCCAACCGGGGTCGAAGTGTGCGATGCCATGATACACGGCGGCCCTTATCCGGCCACCAGCGATGCACGCGGC
AGTTCGGTCGGTACCCTGGCCATTGAACGCTTCCTGCGCCCGGTTTGTTTGCAAAATTACCCGGCCGCATTGTTGCCGCC
AGCGTTACAAGACAGTAATCCACTGGGCCTGTTACGGCTGGTGAACGGTATTTACACCCGAGATCCGATCCACTCACCTG
CCAACAACTAG

Upstream 100 bases:

>100_bases
AGCGCTGGCAAATCGCCCTGAATTGCCGGACGTCGGCCTGTAATTGCCACTCTCGCCCGGCCGCCTGCCGGGCCTGAACA
CCAGCCAACCGGGGGAACCC

Downstream 100 bases:

>100_bases
CCCGGCCGCATCTGCATGCCACCTAATAACAAAAGGGTAAACCCATGACAACCCAAGGCAAATTCAAGAAGCAGCTTACG
CTCACCGATTTGACGTTTAT

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MSNAYTIRGQQFIGGQRRASGEAELVSLRADNGQPTGHRFFSASIAETAAAADAAAQAFTAYSQLSAERRADFLEAIAGQ
LDALDEEFFNYAMQETALPLARLSGERARTSGQMRLFASLLRRGDVHGVRIDCALPQRTPLPRPDLRQYRTALGPVAVFG
ASNFPLAFSTAGGDTAAALAAGCPVVFKAHSGHMITAELTAQAIERAREQQQIPAGVFNMIYGDRIGAELVQHPAIQAVG
FTGSLRGGRALFDLAMRRPQPIPVFAEMSSINPLIIMPQALAQRGQQIARELVASFTLGCGQFCTKPGLIIGQRSEAFSQ
FMGELTEQVNAAAPQPMLNIGTLAHYRSGLAALDQHDGIRHLAGSREAPPFLAAPQLYQADIGLLLSGNPLLQEEVFGPV
AILVTVENHQQLTAALESLQGQLTATLLTDPEDLADAEPLAQLLTRKAGRVLFNGYPTGVEVCDAMIHGGPYPATSDARG
SSVGTLAIERFLRPVCLQNYPAALLPPALQDSNPLGLLRLVNGIYTRDPIHSPANN

Sequences:

>Translated_536_residues
MSNAYTIRGQQFIGGQRRASGEAELVSLRADNGQPTGHRFFSASIAETAAAADAAAQAFTAYSQLSAERRADFLEAIAGQ
LDALDEEFFNYAMQETALPLARLSGERARTSGQMRLFASLLRRGDVHGVRIDCALPQRTPLPRPDLRQYRTALGPVAVFG
ASNFPLAFSTAGGDTAAALAAGCPVVFKAHSGHMITAELTAQAIERAREQQQIPAGVFNMIYGDRIGAELVQHPAIQAVG
FTGSLRGGRALFDLAMRRPQPIPVFAEMSSINPLIIMPQALAQRGQQIARELVASFTLGCGQFCTKPGLIIGQRSEAFSQ
FMGELTEQVNAAAPQPMLNIGTLAHYRSGLAALDQHDGIRHLAGSREAPPFLAAPQLYQADIGLLLSGNPLLQEEVFGPV
AILVTVENHQQLTAALESLQGQLTATLLTDPEDLADAEPLAQLLTRKAGRVLFNGYPTGVEVCDAMIHGGPYPATSDARG
SSVGTLAIERFLRPVCLQNYPAALLPPALQDSNPLGLLRLVNGIYTRDPIHSPANN
>Mature_535_residues
SNAYTIRGQQFIGGQRRASGEAELVSLRADNGQPTGHRFFSASIAETAAAADAAAQAFTAYSQLSAERRADFLEAIAGQL
DALDEEFFNYAMQETALPLARLSGERARTSGQMRLFASLLRRGDVHGVRIDCALPQRTPLPRPDLRQYRTALGPVAVFGA
SNFPLAFSTAGGDTAAALAAGCPVVFKAHSGHMITAELTAQAIERAREQQQIPAGVFNMIYGDRIGAELVQHPAIQAVGF
TGSLRGGRALFDLAMRRPQPIPVFAEMSSINPLIIMPQALAQRGQQIARELVASFTLGCGQFCTKPGLIIGQRSEAFSQF
MGELTEQVNAAAPQPMLNIGTLAHYRSGLAALDQHDGIRHLAGSREAPPFLAAPQLYQADIGLLLSGNPLLQEEVFGPVA
ILVTVENHQQLTAALESLQGQLTATLLTDPEDLADAEPLAQLLTRKAGRVLFNGYPTGVEVCDAMIHGGPYPATSDARGS
SVGTLAIERFLRPVCLQNYPAALLPPALQDSNPLGLLRLVNGIYTRDPIHSPANN

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=406, Percent_Identity=26.6009852216749, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI115387104, Length=363, Percent_Identity=23.9669421487603, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789015, Length=431, Percent_Identity=25.0580046403712, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081896, Length=450, Percent_Identity=26, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786504, Length=299, Percent_Identity=28.0936454849498, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995606, Length=423, Percent_Identity=24.822695035461, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI25143874, Length=339, Percent_Identity=25.6637168141593, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25143876, Length=339, Percent_Identity=25.6637168141593, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362580, Length=395, Percent_Identity=25.0632911392405, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI62472918, Length=395, Percent_Identity=25.0632911392405, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI62472926, Length=395, Percent_Identity=25.0632911392405, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI62472936, Length=395, Percent_Identity=25.0632911392405, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356737, Length=395, Percent_Identity=25.0632911392405, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 57217; Mature: 57086

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAYTIRGQQFIGGQRRASGEAELVSLRADNGQPTGHRFFSASIAETAAAADAAAQAFT
CCCCEEECCHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AYSQLSAERRADFLEAIAGQLDALDEEFFNYAMQETALPLARLSGERARTSGQMRLFASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHH
LRRGDVHGVRIDCALPQRTPLPRPDLRQYRTALGPVAVFGASNFPLAFSTAGGDTAAALA
HHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEEECCCCCHHHHHH
AGCPVVFKAHSGHMITAELTAQAIERAREQQQIPAGVFNMIYGDRIGAELVQHPAIQAVG
CCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEC
FTGSLRGGRALFDLAMRRPQPIPVFAEMSSINPLIIMPQALAQRGQQIARELVASFTLGC
CCCCCCCCHHHHHHHHCCCCCCCEEEHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCH
GQFCTKPGLIIGQRSEAFSQFMGELTEQVNAAAPQPMLNIGTLAHYRSGLAALDQHDGIR
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
HLAGSREAPPFLAAPQLYQADIGLLLSGNPLLQEEVFGPVAILVTVENHQQLTAALESLQ
HHCCCCCCCCCCCCCCHHHCCCCEEECCCCHHHHHHCCCEEEEEEECCHHHHHHHHHHHC
GQLTATLLTDPEDLADAEPLAQLLTRKAGRVLFNGYPTGVEVCDAMIHGGPYPATSDARG
CCEEEEEECCCHHHCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
SSVGTLAIERFLRPVCLQNYPAALLPPALQDSNPLGLLRLVNGIYTRDPIHSPANN
CCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SNAYTIRGQQFIGGQRRASGEAELVSLRADNGQPTGHRFFSASIAETAAAADAAAQAFT
CCCEEECCHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AYSQLSAERRADFLEAIAGQLDALDEEFFNYAMQETALPLARLSGERARTSGQMRLFASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHH
LRRGDVHGVRIDCALPQRTPLPRPDLRQYRTALGPVAVFGASNFPLAFSTAGGDTAAALA
HHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEEECCCCCHHHHHH
AGCPVVFKAHSGHMITAELTAQAIERAREQQQIPAGVFNMIYGDRIGAELVQHPAIQAVG
CCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEC
FTGSLRGGRALFDLAMRRPQPIPVFAEMSSINPLIIMPQALAQRGQQIARELVASFTLGC
CCCCCCCCHHHHHHHHCCCCCCCEEEHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCH
GQFCTKPGLIIGQRSEAFSQFMGELTEQVNAAAPQPMLNIGTLAHYRSGLAALDQHDGIR
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
HLAGSREAPPFLAAPQLYQADIGLLLSGNPLLQEEVFGPVAILVTVENHQQLTAALESLQ
HHCCCCCCCCCCCCCCHHHCCCCEEECCCCHHHHHHCCCEEEEEEECCHHHHHHHHHHHC
GQLTATLLTDPEDLADAEPLAQLLTRKAGRVLFNGYPTGVEVCDAMIHGGPYPATSDARG
CCEEEEEECCCHHHCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
SSVGTLAIERFLRPVCLQNYPAALLPPALQDSNPLGLLRLVNGIYTRDPIHSPANN
CCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]