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The map label for this gene is hcr [H]

Identifier: 157369908

GI number: 157369908

Start: 1819788

End: 1820792

Strand: Reverse

Name: hcr [H]

Synonym: Spro_1665

Alternate gene names: 157369908

Gene position: 1820792-1819788 (Counterclockwise)

Preceding gene: 157369909

Following gene: 157369907

Centisome position: 33.42

GC content: 60.3

Gene sequence:

>1005_bases
ATGACCCAACCCAGCCCACTTTGCCCCAACCGCATGCAGGTGCATTCGATCCAGCAGGAAACCGCCGACGTCTGGACGCT
CAACCTGATCTGCGATGTTTTTTACCCTTATCAACCCGGTCAGTTTGCGCTGGTCAGTATCCGTAATAGCGAAGACACTC
TACGCGCCTATACGCTCTCCTCTTCGCCCGGCCAGAGCCGTTTTCTCAGCATCAGTGTACGTTGCCTGCCGGACGGCGTG
GGTTCGCGCTGGTTAACCGGCGAAGTCAAACCCGGCAACACCCTGTGGCTGTCCGATGCGCAAGGCGAGTTCAGCTGTGA
ACAACATCCGGCCGATCGTTACCTGATGCTGGCGGCCGGCTGCGGCGTAACGCCGATCATCTCCATGTGTCGCTGGCTGG
TGGCCAATCGCCCGACCTGTGATATCGCAGTGATCTTTAACGTACGCACTCCCGCCGATACCATTTTTGCCGAGCAATGG
CGCGAGTTATGCGCCACGCACCCGCAACTGCGACTGACGCTGATGGCCGAACAGGACATTCAACCAGGTTATCTCAATGG
GCGAATCAGTGCCGAAGTGCTGCGCCAGGCGGCGCCGGATATCACTGAGCGCACCGTGATGACCTGCGGCCCGGCCCCCT
ATATGGCTCAGGCAGAACGGCTTTGCCTGCAGCTGGGCGTAGCGGCCGACCGTTTCCATAAAGAGCAGTTCCATACCCCG
GCAGCCACCGATGGCGAACAGGGCGAAGGATTAACCTTGCGCACCGCCCGCCCGCTGCGTGAGTTCCGCGTACCGGTCGG
CAGCACATTGCTGGCGGCAATGGAAGCTCACGTGCTGCCGGTCAACGCCGCCTGCCGCGCTGGTGTGTGTGGTTCATGTA
AAACCCGCATCCTCGAAGGTGACTACACCACCACCAGCAGCATGACTCTGACTGCGGCTGAAATCGCCCAGGGCTATGTA
CTGGCTTGCAGTTGCCAACTGCAAGGTGACGTCACCCTCGCCTGA

Upstream 100 bases:

>100_bases
CCCGATCACCACCGTAGATCAGGATCTGCAAGCCCTGCTCGGCTAATGCTGCTGTTTCTCGGGGCCGCAGATGTCGGCCC
CTTTGCTTTTGAGGTGCCCA

Downstream 100 bases:

>100_bases
TGCTTTCTGCCCCGTTGGCCACGATGGGGCATTTATCGGCAAGCAGGCTTTACCTTCCCCTTCTACACTTTCCCGGTTCC
ATGTTCGTTACTGCGTTTAT

Product: HCP oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTQPSPLCPNRMQVHSIQQETADVWTLNLICDVFYPYQPGQFALVSIRNSEDTLRAYTLSSSPGQSRFLSISVRCLPDGV
GSRWLTGEVKPGNTLWLSDAQGEFSCEQHPADRYLMLAAGCGVTPIISMCRWLVANRPTCDIAVIFNVRTPADTIFAEQW
RELCATHPQLRLTLMAEQDIQPGYLNGRISAEVLRQAAPDITERTVMTCGPAPYMAQAERLCLQLGVAADRFHKEQFHTP
AATDGEQGEGLTLRTARPLREFRVPVGSTLLAAMEAHVLPVNAACRAGVCGSCKTRILEGDYTTTSSMTLTAAEIAQGYV
LACSCQLQGDVTLA

Sequences:

>Translated_334_residues
MTQPSPLCPNRMQVHSIQQETADVWTLNLICDVFYPYQPGQFALVSIRNSEDTLRAYTLSSSPGQSRFLSISVRCLPDGV
GSRWLTGEVKPGNTLWLSDAQGEFSCEQHPADRYLMLAAGCGVTPIISMCRWLVANRPTCDIAVIFNVRTPADTIFAEQW
RELCATHPQLRLTLMAEQDIQPGYLNGRISAEVLRQAAPDITERTVMTCGPAPYMAQAERLCLQLGVAADRFHKEQFHTP
AATDGEQGEGLTLRTARPLREFRVPVGSTLLAAMEAHVLPVNAACRAGVCGSCKTRILEGDYTTTSSMTLTAAEIAQGYV
LACSCQLQGDVTLA
>Mature_333_residues
TQPSPLCPNRMQVHSIQQETADVWTLNLICDVFYPYQPGQFALVSIRNSEDTLRAYTLSSSPGQSRFLSISVRCLPDGVG
SRWLTGEVKPGNTLWLSDAQGEFSCEQHPADRYLMLAAGCGVTPIISMCRWLVANRPTCDIAVIFNVRTPADTIFAEQWR
ELCATHPQLRLTLMAEQDIQPGYLNGRISAEVLRQAAPDITERTVMTCGPAPYMAQAERLCLQLGVAADRFHKEQFHTPA
ATDGEQGEGLTLRTARPLREFRVPVGSTLLAAMEAHVLPVNAACRAGVCGSCKTRILEGDYTTTSSMTLTAAEIAQGYVL
ACSCQLQGDVTLA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=334, Percent_Identity=56.8862275449102, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1787658, Length=339, Percent_Identity=28.023598820059, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788104, Length=325, Percent_Identity=28.6153846153846, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36514; Mature: 36383

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPSPLCPNRMQVHSIQQETADVWTLNLICDVFYPYQPGQFALVSIRNSEDTLRAYTLS
CCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEC
SSPGQSRFLSISVRCLPDGVGSRWLTGEVKPGNTLWLSDAQGEFSCEQHPADRYLMLAAG
CCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEEC
CGVTPIISMCRWLVANRPTCDIAVIFNVRTPADTIFAEQWRELCATHPQLRLTLMAEQDI
CCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCC
QPGYLNGRISAEVLRQAAPDITERTVMTCGPAPYMAQAERLCLQLGVAADRFHKEQFHTP
CCCCCCCCHHHHHHHHHCCCHHHCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCC
AATDGEQGEGLTLRTARPLREFRVPVGSTLLAAMEAHVLPVNAACRAGVCGSCKTRILEG
CCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHEEEEECCHHCCCCCCCCCCEEEEC
DYTTTSSMTLTAAEIAQGYVLACSCQLQGDVTLA
CCEECCCEEEEHHHHHCCEEEEEEEEECCCEEEC
>Mature Secondary Structure 
TQPSPLCPNRMQVHSIQQETADVWTLNLICDVFYPYQPGQFALVSIRNSEDTLRAYTLS
CCCCCCCCCCHHHHHHHHHHHHEEEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEC
SSPGQSRFLSISVRCLPDGVGSRWLTGEVKPGNTLWLSDAQGEFSCEQHPADRYLMLAAG
CCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEEC
CGVTPIISMCRWLVANRPTCDIAVIFNVRTPADTIFAEQWRELCATHPQLRLTLMAEQDI
CCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCC
QPGYLNGRISAEVLRQAAPDITERTVMTCGPAPYMAQAERLCLQLGVAADRFHKEQFHTP
CCCCCCCCHHHHHHHHHCCCHHHCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCC
AATDGEQGEGLTLRTARPLREFRVPVGSTLLAAMEAHVLPVNAACRAGVCGSCKTRILEG
CCCCCCCCCCEEEECCCCHHHHCCCCCHHHHHHHHHEEEEECCHHCCCCCCCCCCEEEEC
DYTTTSSMTLTAAEIAQGYVLACSCQLQGDVTLA
CCEECCCEEEEHHHHHCCEEEEEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]