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The map label for this gene is moaB [H]

Identifier: 157369564

GI number: 157369564

Start: 1452145

End: 1452657

Strand: Direct

Name: moaB [H]

Synonym: Spro_1321

Alternate gene names: 157369564

Gene position: 1452145-1452657 (Clockwise)

Preceding gene: 157369563

Following gene: 157369565

Centisome position: 26.65

GC content: 57.7

Gene sequence:

>513_bases
ATGAGTCATGCCAGCAGTGAATTCATTCCGGCGCATATCGCTATTCTGACCGTTTCGGACAGTCGCGGTGAAGCGGAAGA
CACCTCGGGCCAGTATCTGCAGGAAGCGGCGCTTGAGGCTGGGCATCAGGTGGTGGATCGCGCCATCGTCAAAGACGATA
AATATCAAATCCGCGCACGAATCTCCGCGTGGATCGTCGACGAGCAGGTTCAGGCCGTGCTGATCACCGGGGGCACCGGT
TTTACCGCCAGGGACAACACCCCGGAAGCGCTGCTGCCGCTGTTCGATCGTGAAGTGGAAGGGTTCGGCGAACTGTTCCG
TATGGTGTCCTATGAAGAGATTGGCACCGCCACTATTCAGTCGCGTGCACTGGCCGGAATGGCCAATCAGACGGTGATTT
TTGCCATGCCTGGCTCGACTCGTGCCTGCCGCACCGCCTGGGAACGTATTATTGAAGAGCAGTTGGACGCGCGTCACCGC
CCGTGCAACTTCCTGCCACATTTGAAGAAATAG

Upstream 100 bases:

>100_bases
CAAAAAGCAGACCCACTTCCTGCACCAGGGCAACAGTGGCATCACGCAGAATTTGTCGTTTATCGGCGGATAAATTTTTC
CAATTGCACGGGAGCAAGCA

Downstream 100 bases:

>100_bases
AAACTATGACGCAGCTGACTCACATTAACGCCGCGGGCGAAGCCCATATGGTCGACGTTTCCGCCAAGGCAGAGACGGTG
CGCGAGGCGCGCGCCGAGGC

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSHASSEFIPAHIAILTVSDSRGEAEDTSGQYLQEAALEAGHQVVDRAIVKDDKYQIRARISAWIVDEQVQAVLITGGTG
FTARDNTPEALLPLFDREVEGFGELFRMVSYEEIGTATIQSRALAGMANQTVIFAMPGSTRACRTAWERIIEEQLDARHR
PCNFLPHLKK

Sequences:

>Translated_170_residues
MSHASSEFIPAHIAILTVSDSRGEAEDTSGQYLQEAALEAGHQVVDRAIVKDDKYQIRARISAWIVDEQVQAVLITGGTG
FTARDNTPEALLPLFDREVEGFGELFRMVSYEEIGTATIQSRALAGMANQTVIFAMPGSTRACRTAWERIIEEQLDARHR
PCNFLPHLKK
>Mature_169_residues
SHASSEFIPAHIAILTVSDSRGEAEDTSGQYLQEAALEAGHQVVDRAIVKDDKYQIRARISAWIVDEQVQAVLITGGTGF
TARDNTPEALLPLFDREVEGFGELFRMVSYEEIGTATIQSRALAGMANQTVIFAMPGSTRACRTAWERIIEEQLDARHRP
CNFLPHLKK

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=144, Percent_Identity=31.9444444444444, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI66932975, Length=144, Percent_Identity=31.9444444444444, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1787000, Length=170, Percent_Identity=72.3529411764706, Blast_Score=265, Evalue=9e-73,
Organism=Escherichia coli, GI1786190, Length=143, Percent_Identity=31.4685314685315, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=146, Percent_Identity=33.5616438356164, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136978, Length=141, Percent_Identity=35.4609929078014, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24638841, Length=141, Percent_Identity=35.4609929078014, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18844; Mature: 18713

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHASSEFIPAHIAILTVSDSRGEAEDTSGQYLQEAALEAGHQVVDRAIVKDDKYQIRAR
CCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ISAWIVDEQVQAVLITGGTGFTARDNTPEALLPLFDREVEGFGELFRMVSYEEIGTATIQ
HHHHEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRALAGMANQTVIFAMPGSTRACRTAWERIIEEQLDARHRPCNFLPHLKK
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SHASSEFIPAHIAILTVSDSRGEAEDTSGQYLQEAALEAGHQVVDRAIVKDDKYQIRAR
CCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ISAWIVDEQVQAVLITGGTGFTARDNTPEALLPLFDREVEGFGELFRMVSYEEIGTATIQ
HHHHEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRALAGMANQTVIFAMPGSTRACRTAWERIIEEQLDARHRPCNFLPHLKK
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]