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The map label for this gene is moaC [H]

Identifier: 157369565

GI number: 157369565

Start: 1452663

End: 1453142

Strand: Direct

Name: moaC [H]

Synonym: Spro_1322

Alternate gene names: 157369565

Gene position: 1452663-1453142 (Clockwise)

Preceding gene: 157369564

Following gene: 157369566

Centisome position: 26.66

GC content: 59.38

Gene sequence:

>480_bases
ATGACGCAGCTGACTCACATTAACGCCGCGGGCGAAGCCCATATGGTCGACGTTTCCGCCAAGGCAGAGACGGTGCGCGA
GGCGCGCGCCGAGGCCTTTGTTGAAATGTTGCCGACCACGCTGGCGATGATTATCGAGGGTAGCCATCACAAGGGTGATG
TGTTTGCCACGGCGCGCATTGCCGGTATTCAGGCGGCGAAACGCACCTGGGAGCTGATCCCGCTGTGTCACCCGCTGATG
CTGAGCAAGGTCGAAGTGCAATTGGAAGCACAGCCGGAACACAGCCGGGTGCGGATTGAAACCTGCTGCCGGCTGACCGG
CAAGACCGGCGTCGAAATGGAAGCCTTGACCGCCGCTTCGGTGGCCGCATTGACCATTTACGACATGTGCAAGGCGGTAC
AAAAAGACATGGTGATCGGCCCGGTGCGGCTGCTGGCGAAAAGCGGCGGTAAATCCGGTGATTTTAAGGTGGAACTATGA

Upstream 100 bases:

>100_bases
CTCGTGCCTGCCGCACCGCCTGGGAACGTATTATTGAAGAGCAGTTGGACGCGCGTCACCGCCCGTGCAACTTCCTGCCA
CATTTGAAGAAATAGAAACT

Downstream 100 bases:

>100_bases
TTAACATTCTGTTTTTTGCCCAGGTGCGTGAACTGGTTGGCACCGGCGATCTGTCGATGCCGGCGGATTATCCAACGGTA
GAGGCGCTGCGTAAGGCGCT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTQLTHINAAGEAHMVDVSAKAETVREARAEAFVEMLPTTLAMIIEGSHHKGDVFATARIAGIQAAKRTWELIPLCHPLM
LSKVEVQLEAQPEHSRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEL

Sequences:

>Translated_159_residues
MTQLTHINAAGEAHMVDVSAKAETVREARAEAFVEMLPTTLAMIIEGSHHKGDVFATARIAGIQAAKRTWELIPLCHPLM
LSKVEVQLEAQPEHSRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEL
>Mature_158_residues
TQLTHINAAGEAHMVDVSAKAETVREARAEAFVEMLPTTLAMIIEGSHHKGDVFATARIAGIQAAKRTWELIPLCHPLML
SKVEVQLEAQPEHSRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEL

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=91.7721518987342, Blast_Score=298, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.9530201342282, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=56.0509554140127, Blast_Score=159, Evalue=5e-40,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=56.9444444444444, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17196; Mature: 17065

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLTHINAAGEAHMVDVSAKAETVREARAEAFVEMLPTTLAMIIEGSHHKGDVFATARI
CCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLMLSKVEVQLEAQPEHSRVRIETCCRLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEL
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure 
TQLTHINAAGEAHMVDVSAKAETVREARAEAFVEMLPTTLAMIIEGSHHKGDVFATARI
CCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLMLSKVEVQLEAQPEHSRVRIETCCRLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEL
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA