Click here to switch to the map view.

The map label for this gene is corC [H]

Identifier: 157369459

GI number: 157369459

Start: 1333248

End: 1334126

Strand: Reverse

Name: corC [H]

Synonym: Spro_1216

Alternate gene names: 157369459

Gene position: 1334126-1333248 (Counterclockwise)

Preceding gene: 157369460

Following gene: 157369458

Centisome position: 24.48

GC content: 54.61

Gene sequence:

>879_bases
ATGAGCGACGACCATTCACAAAGCAATGACAGCCCCAGTCCCAAGAAGGGGTTCTTTACTCTTATCCTTAACCAGCTGTT
CCACGGCGAACCTAAAAACCGTGGCGATCTGGTAGAGCTGATCCGTGATTCCGAGCAAAACGACCTGATCGATCCCGATA
CCCGAGACATGCTGGAAGGCGTGATGGATATCGCCGAGCAGCGCGTGCGCGACATCATGATCCCGCGCTCCCAGATGGTA
ACGCTCAAACGTAACCAAACGCTGGAAGAGTGCCTGGACGTGATTATTGAATCCGCCCACTCGCGCTTCCCGGTGATCAG
CGAAGATAAAGATCACATCGAAGGCATTCTGATGGCCAAGGATCTGCTGCCGTTTATGCGCGCAGAGTCCGAGGAATTCA
GCATCGACAAGGTGCTGCGCACCGCAGTGGTGGTGCCGGAAAGCAAGCGGGTCGACCGGATGCTGAAGGAGTTCCGCTCC
CAGCGTTATCACATGGCGATTGTCATTGACGAATTCGGCGGCGTGTCCGGCCTGGTCACTATCGAAGACATTCTGGAACT
GATTGTCGGCGAAATTGAAGACGAGTATGACGACGAGGACGACCTGGACATCCGCCAGCTCAGCCGTCATATGTATACCG
TGCGCGCACTGGCGCCGATTGAAGACTTCAACGAAGCCTTCGGCACCCACTTCAGCGACGACGAGGTCGACACCATCGGT
GGCCTGGTCATGCAAGCCTTCGGCCACCTGCCTGCACGTGGGGAAACCATTGAAATCGAAGGTTACCTATTTAAAGTTGC
GATGGCCGACAGTCGACGTATCATCCAGGTTCATGTAAAAATTCCGGACGATTCTCCGCAACCGAAACTGGAAGAATAA

Upstream 100 bases:

>100_bases
AAAAGACCCCCTCTGACGTCAGCTGATTTCCCCGCAGCCCCTGTATGGGGCTGTCGCTGACTCCCCTAACTCTGACATGA
GTGATATTAACTAAAACGCC

Downstream 100 bases:

>100_bases
ATCGAACATGGCTAAAGCCTCTTACCTTGATCGCCAGTGGGTTCGCGCCCTACTGGCGCTGTTGACTGGTGCCAGTGGCA
CGCTGGCGTTTTCCCCTTAC

Product: transporter-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSDDHSQSNDSPSPKKGFFTLILNQLFHGEPKNRGDLVELIRDSEQNDLIDPDTRDMLEGVMDIAEQRVRDIMIPRSQMV
TLKRNQTLEECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRAESEEFSIDKVLRTAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDDEDDLDIRQLSRHMYTVRALAPIEDFNEAFGTHFSDDEVDTIG
GLVMQAFGHLPARGETIEIEGYLFKVAMADSRRIIQVHVKIPDDSPQPKLEE

Sequences:

>Translated_292_residues
MSDDHSQSNDSPSPKKGFFTLILNQLFHGEPKNRGDLVELIRDSEQNDLIDPDTRDMLEGVMDIAEQRVRDIMIPRSQMV
TLKRNQTLEECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRAESEEFSIDKVLRTAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDDEDDLDIRQLSRHMYTVRALAPIEDFNEAFGTHFSDDEVDTIG
GLVMQAFGHLPARGETIEIEGYLFKVAMADSRRIIQVHVKIPDDSPQPKLEE
>Mature_291_residues
SDDHSQSNDSPSPKKGFFTLILNQLFHGEPKNRGDLVELIRDSEQNDLIDPDTRDMLEGVMDIAEQRVRDIMIPRSQMVT
LKRNQTLEECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRAESEEFSIDKVLRTAVVVPESKRVDRMLKEFRSQ
RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDDEDDLDIRQLSRHMYTVRALAPIEDFNEAFGTHFSDDEVDTIGG
LVMQAFGHLPARGETIEIEGYLFKVAMADSRRIIQVHVKIPDDSPQPKLEE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=33.495145631068, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1786879, Length=292, Percent_Identity=88.013698630137, Blast_Score=496, Evalue=1e-142,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=27.9835390946502, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693175, Length=221, Percent_Identity=27.6018099547511, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788119, Length=222, Percent_Identity=31.0810810810811, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790664, Length=241, Percent_Identity=25.3112033195021, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33369; Mature: 33238

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDHSQSNDSPSPKKGFFTLILNQLFHGEPKNRGDLVELIRDSEQNDLIDPDTRDMLEG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
VMDIAEQRVRDIMIPRSQMVTLKRNQTLEECLDVIIESAHSRFPVISEDKDHIEGILMAK
HHHHHHHHHHHHHCCHHHEEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLLPFMRAESEEFSIDKVLRTAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT
HHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEE
IEDILELIVGEIEDEYDDEDDLDIRQLSRHMYTVRALAPIEDFNEAFGTHFSDDEVDTIG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHH
GLVMQAFGHLPARGETIEIEGYLFKVAMADSRRIIQVHVKIPDDSPQPKLEE
HHHHHHHCCCCCCCCEEEECCEEEEEEECCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SDDHSQSNDSPSPKKGFFTLILNQLFHGEPKNRGDLVELIRDSEQNDLIDPDTRDMLEG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
VMDIAEQRVRDIMIPRSQMVTLKRNQTLEECLDVIIESAHSRFPVISEDKDHIEGILMAK
HHHHHHHHHHHHHCCHHHEEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DLLPFMRAESEEFSIDKVLRTAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT
HHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEE
IEDILELIVGEIEDEYDDEDDLDIRQLSRHMYTVRALAPIEDFNEAFGTHFSDDEVDTIG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHH
GLVMQAFGHLPARGETIEIEGYLFKVAMADSRRIIQVHVKIPDDSPQPKLEE
HHHHHHHCCCCCCCCEEEECCEEEEEEECCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]