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The map label for this gene is lnt [H]

Identifier: 157369458

GI number: 157369458

Start: 1331711

End: 1333240

Strand: Reverse

Name: lnt [H]

Synonym: Spro_1215

Alternate gene names: 157369458

Gene position: 1333240-1331711 (Counterclockwise)

Preceding gene: 157369459

Following gene: 157369457

Centisome position: 24.47

GC content: 59.15

Gene sequence:

>1530_bases
ATGGCTAAAGCCTCTTACCTTGATCGCCAGTGGGTTCGCGCCCTACTGGCGCTGTTGACTGGTGCCAGTGGCACGCTGGC
GTTTTCCCCTTACGATATCTGGCCGGCGGCCATTGTCTCCCTGATTGGCCTGCTGGCCGTGACCCTGAACCGCACCACCA
AACAGTCCGCCCTGCTCGGCTTCTGCTGGGGCTTTGGCCTGTTTGGTAGCGGGATCAACTGGGTTTACGTCAGTATCGCC
GACTTCGGTGGCATGCCGTTCTCCGTCAATATCTTCCTGGTGGCGCTGCTCGCCGCCTATCTGTCTCTGTATACCGGGCT
GTTCGCCGGCTTGCTGGCACGCCTTTGGCCAACCACCAGTTGGTATCGCCTGGCCATTGCTGCGCCGGTGTTGTGGCAGG
TCACCGAGTTTTTACGCGGCTGGGTGCTGACCGGCTTCCCCTGGCTGCAATTTGGCTACAGCCAACTCAACGGCCCGCTG
AAAGGCGTGGCGCCACTGCTGGGGGTGGATACCATTACCTTTATGCTGATGGCGATTGCCGGGTTGCTGGTGTATGCCGT
CAATCAACGTCGCATCACGCCGGCGGTGGTGGCGGTTGCACTGCTGCTGTTGCCGTGGCCGCTGCGCCAGTTGCACTGGT
ATACCCCTCAACCGGACAAGGCGGTCAACGTCGCTATGGTGCAGGGCAATATCGCTCAGTCGATGAAGTGGGACCCGAAA
GCGCTGGTCAGTACGCTGCAAACCTATCTGGATGAAACCCGTCCTTATATGGGCAAAGCGCCGATCATCATTTGGCCGGA
ATCTGCCATCCCGGATTACGAAGCCAGCCAGAACGGCTTCCTGACCATGATGGACGATCTGATGCGTGCCAAAAACAGTA
GCCTGATCACCGGCATTGTTGACGTTCGTGCCACCCCACAGGGCCAGCAAATCTACAACAGCGCCATCGTGTTGGGTGAA
CCGACGCCATACGTTTATCCGGCCAAAGACCGCTACAACAAGCACCATCTGGTGCCGTTCGGCGAGTTTGTTCCGTTGGA
AACCCTGCTGCGACCACTGGCGCCGTTCTTCGACCTGCCGATGTCCTCTTTCAGCCGTGGCGATTACGTCCAGCCTCAGC
TCAGCGTGAAGGGCTACAACCTGACGGCGGCGATCTGCTATGAAATTGTCCTCGGCCAGCAGGTGCGCGATAACTTCCGC
CCGGACACCAACTTCCTGCTGACCATCTCCAACGATGCCTGGTTCGGTCATTCCATCGGCCCGTGGCAGCACTTCCAGAT
GGCGCGCATGCGTGCACTTGAGTTGGGCAGACCTCTGTTGCGCAGCACCAACAACGGCGTGACAGCCGCAGTGGATGCTA
ACGGTGAAGTGATTGCAGAGATCCCGCAGTTCACTCGCAAGGTGCTGGAGGTGAAAATGACCCCCACCACCGGCATTACG
CCTTATGCCCGCTTTGGCGCCACGCCATTGTGGATAATCACCTTGCTGCTCGGCGGCCTGGCGCTGTTCCTCGGCATGCG
TCGTAAATAA

Upstream 100 bases:

>100_bases
CTATTTAAAGTTGCGATGGCCGACAGTCGACGTATCATCCAGGTTCATGTAAAAATTCCGGACGATTCTCCGCAACCGAA
ACTGGAAGAATAAATCGAAC

Downstream 100 bases:

>100_bases
TCCCCCGGGGCGTGGCCATCGGCGCGCCCCGTTGTTTTTCCCTCCCCGTCAAAAATCATTGCCAAATCAACGCTTCTGGC
ACACTCCTTGCTTTACTTAC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MAKASYLDRQWVRALLALLTGASGTLAFSPYDIWPAAIVSLIGLLAVTLNRTTKQSALLGFCWGFGLFGSGINWVYVSIA
DFGGMPFSVNIFLVALLAAYLSLYTGLFAGLLARLWPTTSWYRLAIAAPVLWQVTEFLRGWVLTGFPWLQFGYSQLNGPL
KGVAPLLGVDTITFMLMAIAGLLVYAVNQRRITPAVVAVALLLLPWPLRQLHWYTPQPDKAVNVAMVQGNIAQSMKWDPK
ALVSTLQTYLDETRPYMGKAPIIIWPESAIPDYEASQNGFLTMMDDLMRAKNSSLITGIVDVRATPQGQQIYNSAIVLGE
PTPYVYPAKDRYNKHHLVPFGEFVPLETLLRPLAPFFDLPMSSFSRGDYVQPQLSVKGYNLTAAICYEIVLGQQVRDNFR
PDTNFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGVTAAVDANGEVIAEIPQFTRKVLEVKMTPTTGIT
PYARFGATPLWIITLLLGGLALFLGMRRK

Sequences:

>Translated_509_residues
MAKASYLDRQWVRALLALLTGASGTLAFSPYDIWPAAIVSLIGLLAVTLNRTTKQSALLGFCWGFGLFGSGINWVYVSIA
DFGGMPFSVNIFLVALLAAYLSLYTGLFAGLLARLWPTTSWYRLAIAAPVLWQVTEFLRGWVLTGFPWLQFGYSQLNGPL
KGVAPLLGVDTITFMLMAIAGLLVYAVNQRRITPAVVAVALLLLPWPLRQLHWYTPQPDKAVNVAMVQGNIAQSMKWDPK
ALVSTLQTYLDETRPYMGKAPIIIWPESAIPDYEASQNGFLTMMDDLMRAKNSSLITGIVDVRATPQGQQIYNSAIVLGE
PTPYVYPAKDRYNKHHLVPFGEFVPLETLLRPLAPFFDLPMSSFSRGDYVQPQLSVKGYNLTAAICYEIVLGQQVRDNFR
PDTNFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGVTAAVDANGEVIAEIPQFTRKVLEVKMTPTTGIT
PYARFGATPLWIITLLLGGLALFLGMRRK
>Mature_508_residues
AKASYLDRQWVRALLALLTGASGTLAFSPYDIWPAAIVSLIGLLAVTLNRTTKQSALLGFCWGFGLFGSGINWVYVSIAD
FGGMPFSVNIFLVALLAAYLSLYTGLFAGLLARLWPTTSWYRLAIAAPVLWQVTEFLRGWVLTGFPWLQFGYSQLNGPLK
GVAPLLGVDTITFMLMAIAGLLVYAVNQRRITPAVVAVALLLLPWPLRQLHWYTPQPDKAVNVAMVQGNIAQSMKWDPKA
LVSTLQTYLDETRPYMGKAPIIIWPESAIPDYEASQNGFLTMMDDLMRAKNSSLITGIVDVRATPQGQQIYNSAIVLGEP
TPYVYPAKDRYNKHHLVPFGEFVPLETLLRPLAPFFDLPMSSFSRGDYVQPQLSVKGYNLTAAICYEIVLGQQVRDNFRP
DTNFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGVTAAVDANGEVIAEIPQFTRKVLEVKMTPTTGITP
YARFGATPLWIITLLLGGLALFLGMRRK

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=510, Percent_Identity=67.843137254902, Blast_Score=716, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56445; Mature: 56314

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKASYLDRQWVRALLALLTGASGTLAFSPYDIWPAAIVSLIGLLAVTLNRTTKQSALLG
CCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
FCWGFGLFGSGINWVYVSIADFGGMPFSVNIFLVALLAAYLSLYTGLFAGLLARLWPTTS
HHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WYRLAIAAPVLWQVTEFLRGWVLTGFPWLQFGYSQLNGPLKGVAPLLGVDTITFMLMAIA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GLLVYAVNQRRITPAVVAVALLLLPWPLRQLHWYTPQPDKAVNVAMVQGNIAQSMKWDPK
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEEEECCHHHHCCCCHH
ALVSTLQTYLDETRPYMGKAPIIIWPESAIPDYEASQNGFLTMMDDLMRAKNSSLITGIV
HHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEE
DVRATPQGQQIYNSAIVLGEPTPYVYPAKDRYNKHHLVPFGEFVPLETLLRPLAPFFDLP
EECCCCCCHHHHCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
MSSFSRGDYVQPQLSVKGYNLTAAICYEIVLGQQVRDNFRPDTNFLLTISNDAWFGHSIG
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
PWQHFQMARMRALELGRPLLRSTNNGVTAAVDANGEVIAEIPQFTRKVLEVKMTPTTGIT
CHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHEEEECCCCCCC
PYARFGATPLWIITLLLGGLALFLGMRRK
CHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKASYLDRQWVRALLALLTGASGTLAFSPYDIWPAAIVSLIGLLAVTLNRTTKQSALLG
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
FCWGFGLFGSGINWVYVSIADFGGMPFSVNIFLVALLAAYLSLYTGLFAGLLARLWPTTS
HHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WYRLAIAAPVLWQVTEFLRGWVLTGFPWLQFGYSQLNGPLKGVAPLLGVDTITFMLMAIA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GLLVYAVNQRRITPAVVAVALLLLPWPLRQLHWYTPQPDKAVNVAMVQGNIAQSMKWDPK
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEEEECCHHHHCCCCHH
ALVSTLQTYLDETRPYMGKAPIIIWPESAIPDYEASQNGFLTMMDDLMRAKNSSLITGIV
HHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEE
DVRATPQGQQIYNSAIVLGEPTPYVYPAKDRYNKHHLVPFGEFVPLETLLRPLAPFFDLP
EECCCCCCHHHHCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
MSSFSRGDYVQPQLSVKGYNLTAAICYEIVLGQQVRDNFRPDTNFLLTISNDAWFGHSIG
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
PWQHFQMARMRALELGRPLLRSTNNGVTAAVDANGEVIAEIPQFTRKVLEVKMTPTTGIT
CHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHEEEECCCCCCC
PYARFGATPLWIITLLLGGLALFLGMRRK
CHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]