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The map label for this gene is yyaH [H]

Identifier: 157369241

GI number: 157369241

Start: 1101888

End: 1102271

Strand: Direct

Name: yyaH [H]

Synonym: Spro_0998

Alternate gene names: 157369241

Gene position: 1101888-1102271 (Clockwise)

Preceding gene: 157369240

Following gene: 157369243

Centisome position: 20.22

GC content: 59.9

Gene sequence:

>384_bases
ATGAAAATAGCCCATGTTGCCCTGTGGACCCGTGATATTGATGCGCAGGTGGCGTTCTGGCAGCGTTACTTCAACGGCGT
GGCCGGAGAGTTGTACGTCAGCAAGAATCGCCCGGGTTTTGTTTCCCGTTTTGTCAGCCTGGCTAGCGGCCCAACGCTGG
AGATCATGAGTTTGCCGGAGTTGCTGCCGACGGAGCAGGCCAATGAACGAGTCGGTTGGGCGCATATTGCGCTGTCGGTC
GGCGACGAGGGGCTGGTCGATCAACTGGCGCAGCGTGCGCAGCAGGAGGGGATCCTGCAAGCGCCGCCACGCTGGACCGG
CGATGGTTTTTACGAAGCGATCATCCGCGATCCGGACGGTAACGCCATCGAAATCACCGGTTGA

Upstream 100 bases:

>100_bases
TACCTAGTGACGCCTCCCGGCAGACACCCACAGCTCGAACAGCAGGTGACCCACAGCGGTGGCAAGGTGTTGTACAGCGA
TTCCCCTATTGGAGAGTGAA

Downstream 100 bases:

>100_bases
TCACTCTTCTTCGATAGTCGCGAACTGCTGCGCCAGATAGTCGAGCAGCAGCCGTACCGCGGGCAATAGCCCACGGCGTG
ACGGGTAAACCGCATGCACC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MKIAHVALWTRDIDAQVAFWQRYFNGVAGELYVSKNRPGFVSRFVSLASGPTLEIMSLPELLPTEQANERVGWAHIALSV
GDEGLVDQLAQRAQQEGILQAPPRWTGDGFYEAIIRDPDGNAIEITG

Sequences:

>Translated_127_residues
MKIAHVALWTRDIDAQVAFWQRYFNGVAGELYVSKNRPGFVSRFVSLASGPTLEIMSLPELLPTEQANERVGWAHIALSV
GDEGLVDQLAQRAQQEGILQAPPRWTGDGFYEAIIRDPDGNAIEITG
>Mature_127_residues
MKIAHVALWTRDIDAQVAFWQRYFNGVAGELYVSKNRPGFVSRFVSLASGPTLEIMSLPELLPTEQANERVGWAHIALSV
GDEGLVDQLAQRAQQEGILQAPPRWTGDGFYEAIIRDPDGNAIEITG

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14023; Mature: 14023

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAHVALWTRDIDAQVAFWQRYFNGVAGELYVSKNRPGFVSRFVSLASGPTLEIMSLPE
CCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCC
LLPTEQANERVGWAHIALSVGDEGLVDQLAQRAQQEGILQAPPRWTGDGFYEAIIRDPDG
CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCC
NAIEITG
CEEEECC
>Mature Secondary Structure
MKIAHVALWTRDIDAQVAFWQRYFNGVAGELYVSKNRPGFVSRFVSLASGPTLEIMSLPE
CCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCC
LLPTEQANERVGWAHIALSVGDEGLVDQLAQRAQQEGILQAPPRWTGDGFYEAIIRDPDG
CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCC
NAIEITG
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]