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The map label for this gene is glpR [H]

Identifier: 157369240

GI number: 157369240

Start: 1101074

End: 1101886

Strand: Direct

Name: glpR [H]

Synonym: Spro_0997

Alternate gene names: 157369240

Gene position: 1101074-1101886 (Clockwise)

Preceding gene: 157369238

Following gene: 157369241

Centisome position: 20.21

GC content: 58.3

Gene sequence:

>813_bases
ATGATCACTTGTTCGCCACCGAGAGACAGAATGTCCAAACTGCTCCCCAACCAACGCCATGAAGCGATCCTGACCCTGCT
GCAGCAACAGGGGCAGGTGCTGGCGGTCGAAATGGCCGAACGCCTGAACACCACCGAGGCCACCATTCGGCGCGACCTGC
GCCAGTTGGCGGCTCAGAACCTGTGTAAGCGCATTTACGGCGGCGCACTGGCACCGACACCGGCAACCGGGCCGATCGAG
GCACGACTGCATTTGAGCGGTGATGAGAAGCAGGCTCTGGCGTTGGCCGCACTGGCGTTGATCAAGCAGGATCAGGTGAT
TTTCCTCGATGCCGGCAGCACCCACCTTTACCTGGCCGATCTGTTGCCATCTGACCAAGGGCTGACAGTGGTGACCAATT
CACTGAGTATCGCCGCCAAAATGCTGGAAAGGCCGGGGATCCGCACTATTTTAATCGGCGGTGAGCTGGATGCCGACATC
GGTGGTTGCGTGGACGCTAAAGCGGTGCAGGAAATCGACGGTTTTTATTTCGACATCGCCTTTACCGGCATCTGCGCCTA
TGAGCCGGGCAGCGGTTTTTCGGCGCTGAATTATCAGGATGCCCAGTTCAAGAAACGCCTGCTGACGCGTTCCGGTAACG
TGGCGGTGCTCTGTACCGGCGACAAACTTAATACCTATGCCCCATACAGCTTCCTCGATGCCAGCCGCGTTGATTACCTA
GTGACGCCTCCCGGCAGACACCCACAGCTCGAACAGCAGGTGACCCACAGCGGTGGCAAGGTGTTGTACAGCGATTCCCC
TATTGGAGAGTGA

Upstream 100 bases:

>100_bases
CAGCAACAGCAGCAGTAAATGCCCTCAACGACGGCAACCACAAAACCCGCCAGCCCCGTTTTCGAATTATTTGTACGTTT
ATGCACATTTGTGTACATTC

Downstream 100 bases:

>100_bases
AATGAAAATAGCCCATGTTGCCCTGTGGACCCGTGATATTGATGCGCAGGTGGCGTTCTGGCAGCGTTACTTCAACGGCG
TGGCCGGAGAGTTGTACGTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MITCSPPRDRMSKLLPNQRHEAILTLLQQQGQVLAVEMAERLNTTEATIRRDLRQLAAQNLCKRIYGGALAPTPATGPIE
ARLHLSGDEKQALALAALALIKQDQVIFLDAGSTHLYLADLLPSDQGLTVVTNSLSIAAKMLERPGIRTILIGGELDADI
GGCVDAKAVQEIDGFYFDIAFTGICAYEPGSGFSALNYQDAQFKKRLLTRSGNVAVLCTGDKLNTYAPYSFLDASRVDYL
VTPPGRHPQLEQQVTHSGGKVLYSDSPIGE

Sequences:

>Translated_270_residues
MITCSPPRDRMSKLLPNQRHEAILTLLQQQGQVLAVEMAERLNTTEATIRRDLRQLAAQNLCKRIYGGALAPTPATGPIE
ARLHLSGDEKQALALAALALIKQDQVIFLDAGSTHLYLADLLPSDQGLTVVTNSLSIAAKMLERPGIRTILIGGELDADI
GGCVDAKAVQEIDGFYFDIAFTGICAYEPGSGFSALNYQDAQFKKRLLTRSGNVAVLCTGDKLNTYAPYSFLDASRVDYL
VTPPGRHPQLEQQVTHSGGKVLYSDSPIGE
>Mature_270_residues
MITCSPPRDRMSKLLPNQRHEAILTLLQQQGQVLAVEMAERLNTTEATIRRDLRQLAAQNLCKRIYGGALAPTPATGPIE
ARLHLSGDEKQALALAALALIKQDQVIFLDAGSTHLYLADLLPSDQGLTVVTNSLSIAAKMLERPGIRTILIGGELDADI
GGCVDAKAVQEIDGFYFDIAFTGICAYEPGSGFSALNYQDAQFKKRLLTRSGNVAVLCTGDKLNTYAPYSFLDASRVDYL
VTPPGRHPQLEQQVTHSGGKVLYSDSPIGE

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=230, Percent_Identity=30.8695652173913, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789519, Length=233, Percent_Identity=28.3261802575107, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082344, Length=239, Percent_Identity=26.7782426778243, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=28.2051282051282, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=29.3103448275862, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=27.3127753303965, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=24.901185770751, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789170, Length=210, Percent_Identity=30, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787063, Length=235, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790753, Length=256, Percent_Identity=24.21875, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29225; Mature: 29225

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITCSPPRDRMSKLLPNQRHEAILTLLQQQGQVLAVEMAERLNTTEATIRRDLRQLAAQN
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHH
LCKRIYGGALAPTPATGPIEARLHLSGDEKQALALAALALIKQDQVIFLDAGSTHLYLAD
HHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEE
LLPSDQGLTVVTNSLSIAAKMLERPGIRTILIGGELDADIGGCVDAKAVQEIDGFYFDIA
CCCCCCCCEEEECHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEE
FTGICAYEPGSGFSALNYQDAQFKKRLLTRSGNVAVLCTGDKLNTYAPYSFLDASRVDYL
EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCCCCCCEE
VTPPGRHPQLEQQVTHSGGKVLYSDSPIGE
ECCCCCCCCHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MITCSPPRDRMSKLLPNQRHEAILTLLQQQGQVLAVEMAERLNTTEATIRRDLRQLAAQN
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHH
LCKRIYGGALAPTPATGPIEARLHLSGDEKQALALAALALIKQDQVIFLDAGSTHLYLAD
HHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEE
LLPSDQGLTVVTNSLSIAAKMLERPGIRTILIGGELDADIGGCVDAKAVQEIDGFYFDIA
CCCCCCCCEEEECHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEE
FTGICAYEPGSGFSALNYQDAQFKKRLLTRSGNVAVLCTGDKLNTYAPYSFLDASRVDYL
EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHCCCCCCCEE
VTPPGRHPQLEQQVTHSGGKVLYSDSPIGE
ECCCCCCCCHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]