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The map label for this gene is secM [H]

Identifier: 157369014

GI number: 157369014

Start: 858114

End: 858578

Strand: Direct

Name: secM [H]

Synonym: Spro_0769

Alternate gene names: 157369014

Gene position: 858114-858578 (Clockwise)

Preceding gene: 157369012

Following gene: 157369015

Centisome position: 15.75

GC content: 59.57

Gene sequence:

>465_bases
ATGGTCGCGGCCACGCTTGGCGTACCTACAAATCTGTCCGGCACGCCCGATCAAGCCGCTCTGCCGAGCACATCGTCCAG
CCTGAACCGGCAAAATTCCGCCAGCGGTGCCTTTAATAGCCTGGCATTACTGCAGGAAGCGCATCGCCGCCCGACCTTCA
GTGTCGATTATTGGCACCAGCATGCGCTTCGCACCGTCATTCGTCACCTTTCTTTTGCTCTTGCACCGCAGGCGGTTTTC
GCGCGAGGGCAGGAAAGAGAAGCGGAAGCGACCGAACCCCCATTACAGGTAGCGCAACTGGCGCTGCTTTCTACTCTCAA
CGCGCTGCTGACGCATGAGCAGAAGCCGCCGACCATCATTCGTGATACCCACCATGCCGTGTTACCTGCCTTTGCGCAGC
ATCAGACAGGGTTATGGCTGGCACAGGTGCAGGGCATTCGCGCCGGACCCGCAGCCTTAAGCTGA

Upstream 100 bases:

>100_bases
CGCATAATGGGCTCCGGCGGATAATAAACTCGTGATCGGTATTCTAAATCGTTGGCGACAATTTGGCAGACGTTATTTCT
GGCCCCATCTCCTGTTAGGG

Downstream 100 bases:

>100_bases
TTTCTTGCCCGTCGGGCGACAAAAAACCTAAAAATAACAGCAAATTGACGGCCTGTGTTGGCTGTCATGACAGAGATATC
AAACATCATGTTAGTGAAAT

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVAATLGVPTNLSGTPDQAALPSTSSSLNRQNSASGAFNSLALLQEAHRRPTFSVDYWHQHALRTVIRHLSFALAPQAVF
ARGQEREAEATEPPLQVAQLALLSTLNALLTHEQKPPTIIRDTHHAVLPAFAQHQTGLWLAQVQGIRAGPAALS

Sequences:

>Translated_154_residues
MVAATLGVPTNLSGTPDQAALPSTSSSLNRQNSASGAFNSLALLQEAHRRPTFSVDYWHQHALRTVIRHLSFALAPQAVF
ARGQEREAEATEPPLQVAQLALLSTLNALLTHEQKPPTIIRDTHHAVLPAFAQHQTGLWLAQVQGIRAGPAALS
>Mature_154_residues
MVAATLGVPTNLSGTPDQAALPSTSSSLNRQNSASGAFNSLALLQEAHRRPTFSVDYWHQHALRTVIRHLSFALAPQAVF
ARGQEREAEATEPPLQVAQLALLSTLNALLTHEQKPPTIIRDTHHAVLPAFAQHQTGLWLAQVQGIRAGPAALS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family [H]

Homologues:

Organism=Escherichia coli, GI87081686, Length=156, Percent_Identity=46.1538461538462, Blast_Score=110, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009502
- ProDom:   PD089227 [H]

Pfam domain/function: PF06558 SecM [H]

EC number: NA

Molecular weight: Translated: 16533; Mature: 16533

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAATLGVPTNLSGTPDQAALPSTSSSLNRQNSASGAFNSLALLQEAHRRPTFSVDYWHQ
CCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
HALRTVIRHLSFALAPQAVFARGQEREAEATEPPLQVAQLALLSTLNALLTHEQKPPTII
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
RDTHHAVLPAFAQHQTGLWLAQVQGIRAGPAALS
CCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVAATLGVPTNLSGTPDQAALPSTSSSLNRQNSASGAFNSLALLQEAHRRPTFSVDYWHQ
CCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
HALRTVIRHLSFALAPQAVFARGQEREAEATEPPLQVAQLALLSTLNALLTHEQKPPTII
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
RDTHHAVLPAFAQHQTGLWLAQVQGIRAGPAALS
CCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA