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The map label for this gene is secA [H]

Identifier: 157369015

GI number: 157369015

Start: 858645

End: 861377

Strand: Direct

Name: secA [H]

Synonym: Spro_0770

Alternate gene names: 157369015

Gene position: 858645-861377 (Clockwise)

Preceding gene: 157369014

Following gene: 157369016

Centisome position: 15.76

GC content: 54.26

Gene sequence:

>2733_bases
ATGACAGAGATATCAAACATCATGTTAGTGAAATTATTGACCAAAGTTTTTGGTAGCCGTAACGATCGTACACTGCGTCG
CATGCGTAAAGCGGTTGAACTGATCAATCAGATGGAACCGGACATGGAAAAACTGTCCGATGACGAACTGAAAGCCAAGA
CCAACGAGTTCCGCGCGCGCCTGGAAAAGGGTGAAGTGCTGGAAAACCTGCTGCCGGAAGCCTTCGCCGTAGTGCGCGAA
TCAAGCAAGCGCGTGTTTGGCATGCGTCACTTCGATGTGCAGCTGCTGGGCGGTATGGTACTGAACGATCGCTGTATCGC
AGAGATGCGTACCGGTGAAGGTAAAACCCTGACTGCAACCCTGCCGGCCTATCTGAATGCCCTGAGCGGCCGTGGCGTGC
ACGTGGTTACAGTGAACGACTATTTGGCACAGCGTGACGCCGAAAATAACCGCCCACTGTTCGAGTTCCTCGGCCTGAGC
ATCGGTATCAACCTGCCAGGTATGCCGGCACCGGCCAAGCGTGAAGCTTATGCCGCCGACATTACCTACGGTACCAACAA
CGAATACGGCTTTGACTACCTGCGCGACAACATGGCGTTCAGTCCGGAAGAGCGAGTTCAGCGCAAGCTGCACTATGCGT
TGGTGGATGAGGTCGACTCCATCCTGATCGATGAAGCGCGTACTCCGTTGATCATCTCCGGTCCGGCTGAAGACAGCTCC
GAGATGTACATCAGAGTTAACAAGCTGATCCCTCAGTTGATCCGTCAGGAAAAAGAAGATTCCGATTCCTTCCAGGGCGA
AGGCCACTTCTCGGTTGACGAGAAAGCGCGCCAGGTGCACCTGACCGAACGCGGTCTGATCCTGATCGAAGAAATGCTGA
TGGAAGCCGGCATCATGGATGAAGGCGAGTCACTGTACTCACCGACCAACATCATGCTGATGCACCACGTGACCGCTGCG
CTGCGTGCTCACGTGCTGTTTACCCGTGACGTTGACTACATCGTAAAAGACGGTGAAGTCATTATCGTTGACGAACACAC
CGGCCGTACCATGCAGGGGCGTCGCTGGTCTGATGGTCTGCATCAGGCGGTGGAAGCCAAAGAAGGCGTGGAAATCCAGA
ACGAGAACCAGACGCTGGCCTCCATCACCTTCCAGAACTACTTCCGTCTGTACGAGAAGCTGGCGGGGATGACCGGTACC
GCCGACACCGAAGCCTTTGAATTCAGCTCTATCTACAAGCTCGATACCATAGTGGTGCCGACTAACCGTCCGATGATCCG
TAAGGACATGCCGGATCTGGTCTACATGACCGAGCTGGAGAAGATTGGCGCCATCATTGAAGATATCCGTGAACGTACCG
TCAACGGACAGCCTGTGCTGGTGGGGACCATCTCGATTGAAAAATCCGAAGTGGTTTCCCGCGAACTGACCAAAGCCGGT
ATCGAACACAAGGTTCTGAACGCCAAATTCCACGCCATGGAAGCCGACATCGTGGCCCAGGCCGGCCAAAGCAGTGCGGT
CACTATCGCCACCAACATGGCGGGTCGTGGTACCGATATCGTGCTGGGCGGCAGCTGGCAGGCCGAGATTGAACAGTTGG
AAGACCCAACTGAAGAGCAAATTGCCGAAATCAAGGCAGCCTGGAAAATTCGCCATGATGCGGTACTGGCCGCAGGCGGC
CTGCACATCATTGGTACCGAGCGTCATGAATCACGCCGTATCGATAACCAGTTGCGCGGCCGTTCAGGTCGTCAGGGTGA
TGCCGGTTCATCCCGCTTCTACCTGTCGATGGAAGATGCTCTGATGCGTATTTTCGCCTCGGATCGCGTTTCCAGCATGA
TGCGTAAACTGGGTATGAAAGAAGGTGAGGCCATTGAGCACCCATGGGTCACCAAGGCGATTGCCAATGCACAGCGCAAA
GTGGAAAGCCGCAACTTTGACATTCGTAAGCAACTGCTGGAATACGATGACGTGGCCAACGACCAGCGTCGCGCTATCTA
CAGTCAGCGTAACGAACTGTTGGACGTGTCTGACGTTAGCGAAACCATCACCAGCATCCGTGAAGACGTGTTCAAGACCA
CTATCGACGGTTACATTCAGCCAGAATCGCTGGAAGAAGAGTGGGACATTGAGGGGCTGACAGAGCGCCTGAAAAACGAC
TTCGATCTGGATATGCCAATCGCCGAATGGTTGGACAAAGAGCCTCAGCTGCACGAAGAAACTCTGCGTGAGCGTATTCT
GGAAAAGGCGAAAGAAGAGTACCAGCGTAAAGAAGAAGTGGTTGGCGTCGAGATGATGCGCAACTTCGAGAAGGGTGTGA
TGCTGCAGACACTGGATTCCCTGTGGAAAGAGCATCTGGCGGCGATGGACTACCTGCGTCAGGGTATCCATCTGCGTGGT
TATGCGCAGAAAGATCCTAAGCAGGAGTACAAACGCGAGTCCTTCAACATGTTTGCCACCATGCTGGAATCGCTGAAGCA
TGAAGTCATCAGCGTACTGAGCAAGGTTCAGGTGCGGATGCCGGAAGAGGTTGAAGCGTTGGAGCTGCAGCGTCGTGAAG
AAGCCGAGCGCCTGGCCAAGCAGCAACAGCTGAGCCACTATGAAGAAAATGCGCTGGTTACCGAGGATCCGAATGCACCG
GCAACGGCGGAACGTAAAGTAGGGCGTAACGATCCTTGCCCATGCGGTTCCGGTAAAAAATACAAACAGTGCCACGGCCG
TCTTCAGAGCTAA

Upstream 100 bases:

>100_bases
GGGCATTCGCGCCGGACCCGCAGCCTTAAGCTGATTTCTTGCCCGTCGGGCGACAAAAAACCTAAAAATAACAGCAAATT
GACGGCCTGTGTTGGCTGTC

Downstream 100 bases:

>100_bases
GCCCGGCAATGTTTAACCAATAAAACCCAGGGGTTCAGCGTGCTGAGCCCCTATTTTTTGGGGTGAAGCCCGTGCCCCGA
TGGATCAATCAGGAGGATGC

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 910; Mature: 909

Protein sequence:

>910_residues
MTEISNIMLVKLLTKVFGSRNDRTLRRMRKAVELINQMEPDMEKLSDDELKAKTNEFRARLEKGEVLENLLPEAFAVVRE
SSKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLS
IGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS
EMYIRVNKLIPQLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLILIEEMLMEAGIMDEGESLYSPTNIMLMHHVTAA
LRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGT
ADTEAFEFSSIYKLDTIVVPTNRPMIRKDMPDLVYMTELEKIGAIIEDIRERTVNGQPVLVGTISIEKSEVVSRELTKAG
IEHKVLNAKFHAMEADIVAQAGQSSAVTIATNMAGRGTDIVLGGSWQAEIEQLEDPTEEQIAEIKAAWKIRHDAVLAAGG
LHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSSMMRKLGMKEGEAIEHPWVTKAIANAQRK
VESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETITSIREDVFKTTIDGYIQPESLEEEWDIEGLTERLKND
FDLDMPIAEWLDKEPQLHEETLRERILEKAKEEYQRKEEVVGVEMMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRG
YAQKDPKQEYKRESFNMFATMLESLKHEVISVLSKVQVRMPEEVEALELQRREEAERLAKQQQLSHYEENALVTEDPNAP
ATAERKVGRNDPCPCGSGKKYKQCHGRLQS

Sequences:

>Translated_910_residues
MTEISNIMLVKLLTKVFGSRNDRTLRRMRKAVELINQMEPDMEKLSDDELKAKTNEFRARLEKGEVLENLLPEAFAVVRE
SSKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLS
IGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS
EMYIRVNKLIPQLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLILIEEMLMEAGIMDEGESLYSPTNIMLMHHVTAA
LRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGT
ADTEAFEFSSIYKLDTIVVPTNRPMIRKDMPDLVYMTELEKIGAIIEDIRERTVNGQPVLVGTISIEKSEVVSRELTKAG
IEHKVLNAKFHAMEADIVAQAGQSSAVTIATNMAGRGTDIVLGGSWQAEIEQLEDPTEEQIAEIKAAWKIRHDAVLAAGG
LHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSSMMRKLGMKEGEAIEHPWVTKAIANAQRK
VESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETITSIREDVFKTTIDGYIQPESLEEEWDIEGLTERLKND
FDLDMPIAEWLDKEPQLHEETLRERILEKAKEEYQRKEEVVGVEMMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRG
YAQKDPKQEYKRESFNMFATMLESLKHEVISVLSKVQVRMPEEVEALELQRREEAERLAKQQQLSHYEENALVTEDPNAP
ATAERKVGRNDPCPCGSGKKYKQCHGRLQS
>Mature_909_residues
TEISNIMLVKLLTKVFGSRNDRTLRRMRKAVELINQMEPDMEKLSDDELKAKTNEFRARLEKGEVLENLLPEAFAVVRES
SKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSI
GINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSE
MYIRVNKLIPQLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLILIEEMLMEAGIMDEGESLYSPTNIMLMHHVTAAL
RAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTA
DTEAFEFSSIYKLDTIVVPTNRPMIRKDMPDLVYMTELEKIGAIIEDIRERTVNGQPVLVGTISIEKSEVVSRELTKAGI
EHKVLNAKFHAMEADIVAQAGQSSAVTIATNMAGRGTDIVLGGSWQAEIEQLEDPTEEQIAEIKAAWKIRHDAVLAAGGL
HIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSSMMRKLGMKEGEAIEHPWVTKAIANAQRKV
ESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETITSIREDVFKTTIDGYIQPESLEEEWDIEGLTERLKNDF
DLDMPIAEWLDKEPQLHEETLRERILEKAKEEYQRKEEVVGVEMMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGY
AQKDPKQEYKRESFNMFATMLESLKHEVISVLSKVQVRMPEEVEALELQRREEAERLAKQQQLSHYEENALVTEDPNAPA
TAERKVGRNDPCPCGSGKKYKQCHGRLQS

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=902, Percent_Identity=88.8026607538803, Blast_Score=1660, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 103649; Mature: 103518

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEISNIMLVKLLTKVFGSRNDRTLRRMRKAVELINQMEPDMEKLSDDELKAKTNEFRAR
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
LEKGEVLENLLPEAFAVVRESSKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTAT
HHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEE
LPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSIGINLPGMPAPAKREAYAAD
HHHHHHHHCCCCEEEEEECHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEE
ITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS
EEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
EMYIRVNKLIPQLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLILIEEMLMEAGIMD
CCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEEHHHCCHHHHHHHHHHCCCCC
EGESLYSPTNIMLMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGL
CCCHHCCCHHHHHHHHHHHHHHHHHHEECCCCCEEECCCEEEEECCCCCCCCCCCCHHHH
HQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTIVVP
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEEEC
TNRPMIRKDMPDLVYMTELEKIGAIIEDIRERTVNGQPVLVGTISIEKSEVVSRELTKAG
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHC
IEHKVLNAKFHAMEADIVAQAGQSSAVTIATNMAGRGTDIVLGGSWQAEIEQLEDPTEEQ
CHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHCCCCHHH
IAEIKAAWKIRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDA
HHHHHHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHH
LMRIFASDRVSSMMRKLGMKEGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVAN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
DQRRAIYSQRNELLDVSDVSETITSIREDVFKTTIDGYIQPESLEEEWDIEGLTERLKND
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
FDLDMPIAEWLDKEPQLHEETLRERILEKAKEEYQRKEEVVGVEMMRNFEKGVMLQTLDS
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFNMFATMLESLKHEVISVLSKVQVRM
HHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEEVEALELQRREEAERLAKQQQLSHYEENALVTEDPNAPATAERKVGRNDPCPCGSGKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHCCCCCCCCCCCCCH
YKQCHGRLQS
HHHHCCCCCC
>Mature Secondary Structure 
TEISNIMLVKLLTKVFGSRNDRTLRRMRKAVELINQMEPDMEKLSDDELKAKTNEFRAR
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
LEKGEVLENLLPEAFAVVRESSKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTAT
HHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEE
LPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSIGINLPGMPAPAKREAYAAD
HHHHHHHHCCCCEEEEEECHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEE
ITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS
EEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
EMYIRVNKLIPQLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLILIEEMLMEAGIMD
CCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEEHHHCCHHHHHHHHHHCCCCC
EGESLYSPTNIMLMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGL
CCCHHCCCHHHHHHHHHHHHHHHHHHEECCCCCEEECCCEEEEECCCCCCCCCCCCHHHH
HQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTIVVP
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEEEC
TNRPMIRKDMPDLVYMTELEKIGAIIEDIRERTVNGQPVLVGTISIEKSEVVSRELTKAG
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHC
IEHKVLNAKFHAMEADIVAQAGQSSAVTIATNMAGRGTDIVLGGSWQAEIEQLEDPTEEQ
CHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHCCCCHHH
IAEIKAAWKIRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDA
HHHHHHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHH
LMRIFASDRVSSMMRKLGMKEGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVAN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
DQRRAIYSQRNELLDVSDVSETITSIREDVFKTTIDGYIQPESLEEEWDIEGLTERLKND
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
FDLDMPIAEWLDKEPQLHEETLRERILEKAKEEYQRKEEVVGVEMMRNFEKGVMLQTLDS
CCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFNMFATMLESLKHEVISVLSKVQVRM
HHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEEVEALELQRREEAERLAKQQQLSHYEENALVTEDPNAPATAERKVGRNDPCPCGSGKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHCCCCCCCCCCCCCH
YKQCHGRLQS
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA