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The map label for this gene is mraY [H]

Identifier: 157369003

GI number: 157369003

Start: 845980

End: 847062

Strand: Direct

Name: mraY [H]

Synonym: Spro_0758

Alternate gene names: 157369003

Gene position: 845980-847062 (Clockwise)

Preceding gene: 157369002

Following gene: 157369004

Centisome position: 15.53

GC content: 56.51

Gene sequence:

>1083_bases
ATGTTAGTTTGGCTGGCCGAACATTTGGTCAAATATTATTCCGGCTTCAACGTCTTTTCCTACCTGACGTTCCGAGCCAT
TGTCAGCCTGCTGACCGCGCTGTTCCTCTCCTTGTGGATGGGGCCGCGGGTGATTAAACGCCTGCAGGAGATGTCCTTCG
GCCAGGTGGTGCGTAACGACGGTCCAGAGTCGCATTTCAGCAAGCGCGGCACGCCGACTATGGGCGGCATCATGATCCTG
ACCTCCATCACCGTTTCGGTGCTGATGTGGGCCTATCCGTCCAACCCTTACGTGTGGTGCGTACTGTTCGTGCTGGTGGG
CTACGGCATCGTCGGCTTCGTTGATGACTACCGCAAGGTGGTGCGCAAAGACACCAAAGGGCTGATTGCCCGCTGGAAAT
ATTTCTGGCAGTCGGTGATTGCGCTGGTGGTTGCTTTCGCCATGTATGCCGTAGGAAAAGACACGCCAGCCACCGAGCTG
GTTGTGCCGTTCTTTAAGGACATCATGCCGCAGCTGGGCCTGTTATACGTGCTGTTGGCGTACTTTGTGATTGTCGGCAC
CAGCAACGCGGTCAACCTGACCGACGGTCTGGATGGCCTGGCAATTATGCCAACGGTGTTCGTGGCTGCGGGTTTTGCAC
TGGTGGCTTGGGCTACCGGTAACATGAACTTCGCCAACTACCTGCACATCCCGTATCTGCGTCACGCCGGTGAATTGGTG
ATTGTCTGTACTGCCATCGTGGGCGCCGGTCTGGGTTTCCTGTGGTTCAACACCTACCCGGCTCAGGTCTTTATGGGTGA
TGTTGGCTCACTGGCACTGGGCGGCGCGCTGGGCACTATCGCGGTGCTGCTGCGCCAAGAGTTTTTACTGTTGATTATGG
GTGGCGTATTCGTGGTTGAAACGCTGTCGGTAATTTTGCAGGTGGGGTCGTTCAAGCTGCGCGGACAACGTATTTTCCGC
ATGGCACCGATTCACCACCACTATGAATTGAAGGGCTGGCCAGAGCCGCGCGTGATCGTGCGCTTCTGGATTATTTCGCT
GATGCTGGTGCTGATTGGCCTGGCGACGCTGAAGGTGCGGTAA

Upstream 100 bases:

>100_bases
CGGAATTACTGTCAGAACATGCGGTAATTACCGTGTTAATCAAGGGTTCACGTAGTGCCGCAATGGAGCAGGTAGTACGC
GCGTTACAGGAGAAAGCACC

Downstream 100 bases:

>100_bases
TTATGGCGGATTATCAGGGTAAAAAAGTAGTCATCATCGGGCTGGGCCTTACCGGCCTGTCCTGTGTTGATTTCTTTATG
GCGCGCGGCGTGACGCCACG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFLSLWMGPRVIKRLQEMSFGQVVRNDGPESHFSKRGTPTMGGIMIL
TSITVSVLMWAYPSNPYVWCVLFVLVGYGIVGFVDDYRKVVRKDTKGLIARWKYFWQSVIALVVAFAMYAVGKDTPATEL
VVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLLIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR

Sequences:

>Translated_360_residues
MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFLSLWMGPRVIKRLQEMSFGQVVRNDGPESHFSKRGTPTMGGIMIL
TSITVSVLMWAYPSNPYVWCVLFVLVGYGIVGFVDDYRKVVRKDTKGLIARWKYFWQSVIALVVAFAMYAVGKDTPATEL
VVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLLIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
>Mature_360_residues
MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFLSLWMGPRVIKRLQEMSFGQVVRNDGPESHFSKRGTPTMGGIMIL
TSITVSVLMWAYPSNPYVWCVLFVLVGYGIVGFVDDYRKVVRKDTKGLIARWKYFWQSVIALVVAFAMYAVGKDTPATEL
VVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLLIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=92.5, Blast_Score=661, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40091; Mature: 40091

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFLSLWMGPRVIKRLQEMSFGQVVRND
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGIMILTSITVSVLMWAYPSNPYVWCVLFVLVGYGIVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRKDTKGLIARWKYFWQSVIALVVAFAMYAVGKDTPATELVVPFFKDIMPQLGLLYVLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHEEECHHHHHCCCHH
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLLIMGGVFVVE
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
HHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFLSLWMGPRVIKRLQEMSFGQVVRND
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGIMILTSITVSVLMWAYPSNPYVWCVLFVLVGYGIVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRKDTKGLIARWKYFWQSVIALVVAFAMYAVGKDTPATELVVPFFKDIMPQLGLLYVLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHEEECHHHHHCCCHH
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLLIMGGVFVVE
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
HHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA