| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is slt [H]
Identifier: 157368920
GI number: 157368920
Start: 743047
End: 744975
Strand: Direct
Name: slt [H]
Synonym: Spro_0675
Alternate gene names: 157368920
Gene position: 743047-744975 (Clockwise)
Preceding gene: 157368915
Following gene: 157368921
Centisome position: 13.64
GC content: 59.31
Gene sequence:
>1929_bases ATGGTCAAGGTAGACAAGTGGCGGTTTTTGGCTGTGGGCCTGTGCCTGACGGCATTTTCAAGCGCCGCATTGGCGGATTC CCTGGACGCTCAGCGTCAGCGCTACCTGCAGATCAAGCAGGCGTGGGACAGCAAACAGATGGACGTGGTGGCGCAACTGA TGCCGACGCTGCGTGATTACCCGCTTTACCCTTATCTGGAATACCGTGAGCTGACGCAAGATCTCAGCCAGGTCGGATTC TCTGAGGTGAATGACTTTATCAAGCAGCATCCGACGCTGCCGCCGGCCAAATCGCTGGCCCCGCGTTTTGTTAATGAACT GGCGCGGCGTGAAGACTGGCGTACTCTGCTGGCCTTCAGCCCGCAGGCGCCGAAACCCATTGCTGCGCGTTGCAATTACT ACTATGCCAAATGGGCCACTGGCGATCAGACCGCGGCCTGGAGCGGTGTCGACGACATCTGGATGAGCGGTAAATCGCTG CCGGGAGCCTGTGATAAGTTGTTCAGCGTCTGGCAAGGGGCCGGTAAACAAACGCCAACGGCTATTCTGGAGCGTATGAA ACTGGCGTTGAAAGAGGGCAACAGTGGCCTGGTGAACAGCCTCTATCGCCAATTGCCGTCAGATTATCAGACCATGGGTG ATGCCCTGGTGCGCCTGCAAAACGATCCTGCGACGGTTGAGTCCTTTGCCCGCAGCGTGGGGCCGACCGACTTTACCCGC GCAGCGACCGGTATCGCCTTCGAACGCCTGGCGCGTCAGGATGCGGAAAACGCCCGGGCGATGATCCCAACCCTCGTCCG GCTGCAGAAAATGAGCGACAGCGAGCGGCTGGGGCTGGAGGAAGCGGTGGCCTGGCGCCTGATGGGCAGCGATGCGACCT TTGAACAGACCCAGTGGCGCGACAAGGTGATCCTGCGTAGCCAGTCACCGGCACTGCTGGAGCGCCGCGTGCGTATGGCG CTGGGGGCCGGCGATCGCCAGGGGGTGGCGACCTGGCTGGCGCGTCTGCCGACCGAGTCACGCAATAAAGATGAATGGCG CTATTGGCGTGCGAGCATGTTACTGGACGAAGGCAAACGCAGCGAAGGGGAAGAGATCCTGCGTCGGCTGATGACCGAAC GTGGCTTCTACCCGATGGTGGCGGCACAGAAACTGAATACGCCTTACCCGGTGATGGTGGCGGTAGCGGCAAAACCCCGC GCTTCATTGGTGGATGGCCCGGAAATTGCCCGGGTGCGCGAGTTGATGTACTGGAATATGGATAACCTGGCGCGCAGTGA GTGGACTTCCTTCGTGGCCAGTCGCAGCCGCCCGGAACAGGAAGCGCTGGCGCGTTATGCCTTCGAGCAGAAATGGGCCG ATCTCAGCGTGCAGGCAACTATTGTCGGCAAAATGTGGGACCACCTTGAGGAACGTTTCCCGGTAGCCTGGCCGCAAGAA TTCCGCGCCGCGACCGATGACAAGGGGATAACGCCGAGTTATGCCATGGCGATTGCCCGTCAGGAGAGCGCCTGGAACCC GAAAGCACAGTCACCGGTAGGGGCCAGCGGCCTGATGCAGGTGATGCCACGTACCGCGCAGCATACCGTGCAGATGTACA ATATTCCCGGTTACTCAAGCCCCAGCCAACTGCTTGATCCGCGTGTCAATATTACCATCGGCACCAGTTATCTGGAGTAT GTTTACCAGCAGTTTGGTCGCAACCGGATCCTGTCATCGGCGGCTTACAATGCCGGTCCGTCTCGGGTGAATACCTGGTT GGGTAACAGTGAAGGGCGGGTTGATGCCGTGGCATTTGTCGAAAGCATCCCGTTCTCAGAAACCCGTTCTTACGTGAAGA ACGTGTTGGCATACGACGCATTTTATCGCTATCTCATGCATCGGCCGGCTAAAGTGCTGACCGACGCCGAGTGGCAGAGG CGTTATTGA
Upstream 100 bases:
>100_bases GGAGAGTCGGGTTCACCGATCCGTTGGCTGCTGACGTAGCGCGGCAACGGGCTGAAGCGGCTCTGGCAACACCATCAGCA TTAGCGAGGAAAGAGTCAGT
Downstream 100 bases:
>100_bases TTTTGACGTCGCTATGGTATGCTGCTGTACTAGTTAAATAGTATGGTGGCTTGCCATGACGCAATTATCGCTTAACGACC CGGCTCTTTCAGAACAAGGT
Product: lytic murein transglycosylase
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 642; Mature: 642
Protein sequence:
>642_residues MVKVDKWRFLAVGLCLTAFSSAALADSLDAQRQRYLQIKQAWDSKQMDVVAQLMPTLRDYPLYPYLEYRELTQDLSQVGF SEVNDFIKQHPTLPPAKSLAPRFVNELARREDWRTLLAFSPQAPKPIAARCNYYYAKWATGDQTAAWSGVDDIWMSGKSL PGACDKLFSVWQGAGKQTPTAILERMKLALKEGNSGLVNSLYRQLPSDYQTMGDALVRLQNDPATVESFARSVGPTDFTR AATGIAFERLARQDAENARAMIPTLVRLQKMSDSERLGLEEAVAWRLMGSDATFEQTQWRDKVILRSQSPALLERRVRMA LGAGDRQGVATWLARLPTESRNKDEWRYWRASMLLDEGKRSEGEEILRRLMTERGFYPMVAAQKLNTPYPVMVAVAAKPR ASLVDGPEIARVRELMYWNMDNLARSEWTSFVASRSRPEQEALARYAFEQKWADLSVQATIVGKMWDHLEERFPVAWPQE FRAATDDKGITPSYAMAIARQESAWNPKAQSPVGASGLMQVMPRTAQHTVQMYNIPGYSSPSQLLDPRVNITIGTSYLEY VYQQFGRNRILSSAAYNAGPSRVNTWLGNSEGRVDAVAFVESIPFSETRSYVKNVLAYDAFYRYLMHRPAKVLTDAEWQR RY
Sequences:
>Translated_642_residues MVKVDKWRFLAVGLCLTAFSSAALADSLDAQRQRYLQIKQAWDSKQMDVVAQLMPTLRDYPLYPYLEYRELTQDLSQVGF SEVNDFIKQHPTLPPAKSLAPRFVNELARREDWRTLLAFSPQAPKPIAARCNYYYAKWATGDQTAAWSGVDDIWMSGKSL PGACDKLFSVWQGAGKQTPTAILERMKLALKEGNSGLVNSLYRQLPSDYQTMGDALVRLQNDPATVESFARSVGPTDFTR AATGIAFERLARQDAENARAMIPTLVRLQKMSDSERLGLEEAVAWRLMGSDATFEQTQWRDKVILRSQSPALLERRVRMA LGAGDRQGVATWLARLPTESRNKDEWRYWRASMLLDEGKRSEGEEILRRLMTERGFYPMVAAQKLNTPYPVMVAVAAKPR ASLVDGPEIARVRELMYWNMDNLARSEWTSFVASRSRPEQEALARYAFEQKWADLSVQATIVGKMWDHLEERFPVAWPQE FRAATDDKGITPSYAMAIARQESAWNPKAQSPVGASGLMQVMPRTAQHTVQMYNIPGYSSPSQLLDPRVNITIGTSYLEY VYQQFGRNRILSSAAYNAGPSRVNTWLGNSEGRVDAVAFVESIPFSETRSYVKNVLAYDAFYRYLMHRPAKVLTDAEWQR RY >Mature_642_residues MVKVDKWRFLAVGLCLTAFSSAALADSLDAQRQRYLQIKQAWDSKQMDVVAQLMPTLRDYPLYPYLEYRELTQDLSQVGF SEVNDFIKQHPTLPPAKSLAPRFVNELARREDWRTLLAFSPQAPKPIAARCNYYYAKWATGDQTAAWSGVDDIWMSGKSL PGACDKLFSVWQGAGKQTPTAILERMKLALKEGNSGLVNSLYRQLPSDYQTMGDALVRLQNDPATVESFARSVGPTDFTR AATGIAFERLARQDAENARAMIPTLVRLQKMSDSERLGLEEAVAWRLMGSDATFEQTQWRDKVILRSQSPALLERRVRMA LGAGDRQGVATWLARLPTESRNKDEWRYWRASMLLDEGKRSEGEEILRRLMTERGFYPMVAAQKLNTPYPVMVAVAAKPR ASLVDGPEIARVRELMYWNMDNLARSEWTSFVASRSRPEQEALARYAFEQKWADLSVQATIVGKMWDHLEERFPVAWPQE FRAATDDKGITPSYAMAIARQESAWNPKAQSPVGASGLMQVMPRTAQHTVQMYNIPGYSSPSQLLDPRVNITIGTSYLEY VYQQFGRNRILSSAAYNAGPSRVNTWLGNSEGRVDAVAFVESIPFSETRSYVKNVLAYDAFYRYLMHRPAKVLTDAEWQR RY
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=637, Percent_Identity=63.5792778649921, Blast_Score=860, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 72930; Mature: 72930
Theoretical pI: Translated: 9.48; Mature: 9.48
Prosite motif: PS00922 TRANSGLYCOSYLASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKVDKWRFLAVGLCLTAFSSAALADSLDAQRQRYLQIKQAWDSKQMDVVAQLMPTLRDY CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC PLYPYLEYRELTQDLSQVGFSEVNDFIKQHPTLPPAKSLAPRFVNELARREDWRTLLAFS CCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC PQAPKPIAARCNYYYAKWATGDQTAAWSGVDDIWMSGKSLPGACDKLFSVWQGAGKQTPT CCCCCCHHHHCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHH AILERMKLALKEGNSGLVNSLYRQLPSDYQTMGDALVRLQNDPATVESFARSVGPTDFTR HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH AATGIAFERLARQDAENARAMIPTLVRLQKMSDSERLGLEEAVAWRLMGSDATFEQTQWR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCCCCCHHHHHHH DKVILRSQSPALLERRVRMALGAGDRQGVATWLARLPTESRNKDEWRYWRASMLLDEGKR HHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC SEGEEILRRLMTERGFYPMVAAQKLNTPYPVMVAVAAKPRASLVDGPEIARVRELMYWNM CCHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCH DNLARSEWTSFVASRSRPEQEALARYAFEQKWADLSVQATIVGKMWDHLEERFPVAWPQE HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCHH FRAATDDKGITPSYAMAIARQESAWNPKAQSPVGASGLMQVMPRTAQHTVQMYNIPGYSS HHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHEEEEECCCCCC PSQLLDPRVNITIGTSYLEYVYQQFGRNRILSSAAYNAGPSRVNTWLGNSEGRVDAVAFV CHHHCCCCCEEEECHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHH ESIPFSETRSYVKNVLAYDAFYRYLMHRPAKVLTDAEWQRRY HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCC >Mature Secondary Structure MVKVDKWRFLAVGLCLTAFSSAALADSLDAQRQRYLQIKQAWDSKQMDVVAQLMPTLRDY CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC PLYPYLEYRELTQDLSQVGFSEVNDFIKQHPTLPPAKSLAPRFVNELARREDWRTLLAFS CCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC PQAPKPIAARCNYYYAKWATGDQTAAWSGVDDIWMSGKSLPGACDKLFSVWQGAGKQTPT CCCCCCHHHHCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHH AILERMKLALKEGNSGLVNSLYRQLPSDYQTMGDALVRLQNDPATVESFARSVGPTDFTR HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH AATGIAFERLARQDAENARAMIPTLVRLQKMSDSERLGLEEAVAWRLMGSDATFEQTQWR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCCCCCHHHHHHH DKVILRSQSPALLERRVRMALGAGDRQGVATWLARLPTESRNKDEWRYWRASMLLDEGKR HHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC SEGEEILRRLMTERGFYPMVAAQKLNTPYPVMVAVAAKPRASLVDGPEIARVRELMYWNM CCHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCH DNLARSEWTSFVASRSRPEQEALARYAFEQKWADLSVQATIVGKMWDHLEERFPVAWPQE HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCHH FRAATDDKGITPSYAMAIARQESAWNPKAQSPVGASGLMQVMPRTAQHTVQMYNIPGYSS HHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHEEEEECCCCCC PSQLLDPRVNITIGTSYLEYVYQQFGRNRILSSAAYNAGPSRVNTWLGNSEGRVDAVAFV CHHHCCCCCEEEECHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHH ESIPFSETRSYVKNVLAYDAFYRYLMHRPAKVLTDAEWQRRY HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]