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The map label for this gene is yhcS [C]

Identifier: 157368915

GI number: 157368915

Start: 737009

End: 737920

Strand: Direct

Name: yhcS [C]

Synonym: Spro_0670

Alternate gene names: 157368915

Gene position: 737009-737920 (Clockwise)

Preceding gene: 157368913

Following gene: 157368920

Centisome position: 13.53

GC content: 58.88

Gene sequence:

>912_bases
ATGAGGTTTAAACAGCTTCAGGATATGGCATTGTTTGCGCTGGTGGCTGAATGTGGCAGCTATACCGCCGCCGCCAAACG
GGCTGCCTTGCCAAAGTCCAGCGTCAGCCAGCGCATTAGTCAGTTGGAACAGACGCTGGGCCTGCGGCTGTTGAACCGCA
CCACCCGTCAGCTCAATCTGACCTTTGCCGGTGAACGTTATCTGGAACACTGCCAGGAGATGCTGTCCGCCGCCGAACGG
GCCGATCTGGCGCTGCAACGGCTGCGTGATAACCCCAGTGGGCGGTTGCGCATCTCGACCCCCGCCGGGTTGGGGGCAAC
CTTGCTGGCGCGGCTGGCGGCGGATTTCCAGCGGCAATATCCGGATGTCTCGCTGGAGGTGTCGGTATCTGATGCCATGG
TAGATATGGTGCAGGAGGGATTCGATGCCGCGTTGCGAACCGGTAAGCCTCAGGATTCTTCACTGATTGGCCGTCGTTTG
GGGCATGCGCCACGTTATTTGCTGGCGTCGCCGGCCTATCTGGCGCAGTCCCCGCAGATTGTCGATCCGCAACAGTTGCA
GCAGCACCGATGTATTGCACACAGCTCCTGGCCGGTCTGGAGTCTGCGTCGGGGCGACGAGTATTTTCGTTGGCAGCTGC
CGATGCGGCATGTTACCGATAATCTGCTGTACGCGCGTGAATGTGCGATTGCCGGTGCGGGTATCACCATGCTACCGGCC
TTTCTCAGCCGTGAGGTGGTGGCGCAAAAACAACTGGTCGAGGTGTTGCCGGAATGGCAAGCGGAAGGCAATGAGCTGTA
TTTGGTTTATCCAAGCCGCAAGCTGAATTCACCGGCGCTGGCCTGTTTTATCGACGTGGTATTGCAACACCCGGTGTTTG
ACGATTATGCCCGCGAGCTGGCGTGGGAATAA

Upstream 100 bases:

>100_bases
ATGACTGTGCTCCTTTCGAATGAATACCCTCAGTGTAGACCTGTTGGCAGTTGATGATAAGATGGACAATAACTAACTGA
GTGTTCGTTTGAGGTGAACA

Downstream 100 bases:

>100_bases
AAAAAGCGCCGCAGGCGGCGCTTCAGAGTGATGACAAAGCCCGTTATTAGGGAGAGCGTGCCGAAGGGGTCGTAGCGGCT
TGCCCGCCGGAGTGCCCCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MRFKQLQDMALFALVAECGSYTAAAKRAALPKSSVSQRISQLEQTLGLRLLNRTTRQLNLTFAGERYLEHCQEMLSAAER
ADLALQRLRDNPSGRLRISTPAGLGATLLARLAADFQRQYPDVSLEVSVSDAMVDMVQEGFDAALRTGKPQDSSLIGRRL
GHAPRYLLASPAYLAQSPQIVDPQQLQQHRCIAHSSWPVWSLRRGDEYFRWQLPMRHVTDNLLYARECAIAGAGITMLPA
FLSREVVAQKQLVEVLPEWQAEGNELYLVYPSRKLNSPALACFIDVVLQHPVFDDYARELAWE

Sequences:

>Translated_303_residues
MRFKQLQDMALFALVAECGSYTAAAKRAALPKSSVSQRISQLEQTLGLRLLNRTTRQLNLTFAGERYLEHCQEMLSAAER
ADLALQRLRDNPSGRLRISTPAGLGATLLARLAADFQRQYPDVSLEVSVSDAMVDMVQEGFDAALRTGKPQDSSLIGRRL
GHAPRYLLASPAYLAQSPQIVDPQQLQQHRCIAHSSWPVWSLRRGDEYFRWQLPMRHVTDNLLYARECAIAGAGITMLPA
FLSREVVAQKQLVEVLPEWQAEGNELYLVYPSRKLNSPALACFIDVVLQHPVFDDYARELAWE
>Mature_303_residues
MRFKQLQDMALFALVAECGSYTAAAKRAALPKSSVSQRISQLEQTLGLRLLNRTTRQLNLTFAGERYLEHCQEMLSAAER
ADLALQRLRDNPSGRLRISTPAGLGATLLARLAADFQRQYPDVSLEVSVSDAMVDMVQEGFDAALRTGKPQDSSLIGRRL
GHAPRYLLASPAYLAQSPQIVDPQQLQQHRCIAHSSWPVWSLRRGDEYFRWQLPMRHVTDNLLYARECAIAGAGITMLPA
FLSREVVAQKQLVEVLPEWQAEGNELYLVYPSRKLNSPALACFIDVVLQHPVFDDYARELAWE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=280, Percent_Identity=32.1428571428571, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI145693193, Length=279, Percent_Identity=34.7670250896057, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=30.2405498281787, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=30.952380952381, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=29.4520547945205, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=30.9278350515464, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789440, Length=268, Percent_Identity=27.6119402985075, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790011, Length=248, Percent_Identity=24.1935483870968, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=297, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788706, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786713, Length=256, Percent_Identity=28.125, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787806, Length=266, Percent_Identity=27.0676691729323, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=33.6206896551724, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=291, Percent_Identity=24.0549828178694, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=249, Percent_Identity=24.8995983935743, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786448, Length=278, Percent_Identity=27.6978417266187, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=118, Percent_Identity=31.3559322033898, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082132, Length=286, Percent_Identity=24.4755244755245, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34079; Mature: 34079

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKQLQDMALFALVAECGSYTAAAKRAALPKSSVSQRISQLEQTLGLRLLNRTTRQLNL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TFAGERYLEHCQEMLSAAERADLALQRLRDNPSGRLRISTPAGLGATLLARLAADFQRQY
EECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHC
PDVSLEVSVSDAMVDMVQEGFDAALRTGKPQDSSLIGRRLGHAPRYLLASPAYLAQSPQI
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCHHHHCCCCC
VDPQQLQQHRCIAHSSWPVWSLRRGDEYFRWQLPMRHVTDNLLYARECAIAGAGITMLPA
CCHHHHHHHHHHHCCCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHH
FLSREVVAQKQLVEVLPEWQAEGNELYLVYPSRKLNSPALACFIDVVLQHPVFDDYAREL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
AWE
CCC
>Mature Secondary Structure
MRFKQLQDMALFALVAECGSYTAAAKRAALPKSSVSQRISQLEQTLGLRLLNRTTRQLNL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TFAGERYLEHCQEMLSAAERADLALQRLRDNPSGRLRISTPAGLGATLLARLAADFQRQY
EECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHC
PDVSLEVSVSDAMVDMVQEGFDAALRTGKPQDSSLIGRRLGHAPRYLLASPAYLAQSPQI
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCHHHHCCCCC
VDPQQLQQHRCIAHSSWPVWSLRRGDEYFRWQLPMRHVTDNLLYARECAIAGAGITMLPA
CCHHHHHHHHHHHCCCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHH
FLSREVVAQKQLVEVLPEWQAEGNELYLVYPSRKLNSPALACFIDVVLQHPVFDDYAREL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
AWE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]