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The map label for this gene is serB [H]

Identifier: 157368911

GI number: 157368911

Start: 732131

End: 733108

Strand: Direct

Name: serB [H]

Synonym: Spro_0666

Alternate gene names: 157368911

Gene position: 732131-733108 (Clockwise)

Preceding gene: 157368909

Following gene: 157368912

Centisome position: 13.44

GC content: 57.26

Gene sequence:

>978_bases
ATGTCGAATAGTCTGACCTATTGCGATCTCCCGGCAGAGATCTCTCAATGGCCGGGTCTTCCCCTTTCGCTGAGCGGTGA
CGAAGTGATGCCGCTGGATTATCGGGCGGGTCATACCGGTTGGCTATTATATGGCAGAGAACTGAACAAAACGCGCATTA
CCGATTTCCAGCGCAAGCTGGGTGCGGCGATGGTGATTGTTACCGCCTGGTGCGTCGAGGACTATCAGGTGGTGCGTCTG
GCTGGCACCCTGACGGCACGCGCCAAGCTGTTGGCGGCGGAGAGCGGGCTGGATGTGGCTCCTCTAGGCAAAATTCCTCA
TTTGCGCACCCCTGGGCTGCTGGTGATGGATATGGACTCTACGGCGATAGAAATTGAATGCATCGACGAGATCGCCAAAC
TGGCAGGCGTCGGTGAGCAAGTGTCTGAAGTCACCGAACGTGCGATGCGGGGTGAACTGGATTTTACCGCCAGCCTGCGC
CAACGCGTCGGCACGCTGAAAGGCGCCGATGCCAATATCCTCAAGCAGGTGCGCGATGAGCTGCCACTGATGCCTGGGCT
GGTCAACCTGGTGCGCAAGCTGCAGGCGATGGACTGGCACGTGGCGATCGCTTCCGGCGGTTTCACCTATTATGCCGAGT
ACCTGCGCGATAAACTAAAATTGGTGGCGGTGGCGGCTAATGAGCTGGAAATTCGCGACGGCAAACTGACCGGTGAAGTG
CTGGGACCGATAGTCGATGCGCAGTTTAAAGCCGATACGCTGGTCGCACTGGCGGAAAAACTGGGTATTCCGCCGCAGCA
AACCGTGGCCATCGGCGACGGTGCCAACGATTTAAAAATGATGCAGGTTGCCGGGTTGGGCATTGCCTATCACGCCAAAC
CGAAAGTCTATGAGAAGGCGCAGGTGTCGATTCGCCATGCTGACCTGATTGGCGTGCTGTGTGTACTGACCGGTAGCCTG
AAACACGAAGTTCGCTAA

Upstream 100 bases:

>100_bases
GTTCCTTGGGCATCTTGGACACTTTATGTTGCCAGAAGCAATGGCGATAGGATAGCTTGATGCGTCGTTTTATCATGCAG
TGTTTTTTCAGGAGTTAAGG

Downstream 100 bases:

>100_bases
AGTTGACCCTGATCCGGCGATAATGCCAGACAGCGGCAATGTGGTAAAAACAGAGGTAATACGTGGCAAAAGCAGCAAAA
CGGGCGTTTGTATGTAATGA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSNSLTYCDLPAEISQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRELNKTRITDFQRKLGAAMVIVTAWCVEDYQVVRL
AGTLTARAKLLAAESGLDVAPLGKIPHLRTPGLLVMDMDSTAIEIECIDEIAKLAGVGEQVSEVTERAMRGELDFTASLR
QRVGTLKGADANILKQVRDELPLMPGLVNLVRKLQAMDWHVAIASGGFTYYAEYLRDKLKLVAVAANELEIRDGKLTGEV
LGPIVDAQFKADTLVALAEKLGIPPQQTVAIGDGANDLKMMQVAGLGIAYHAKPKVYEKAQVSIRHADLIGVLCVLTGSL
KHEVR

Sequences:

>Translated_325_residues
MSNSLTYCDLPAEISQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRELNKTRITDFQRKLGAAMVIVTAWCVEDYQVVRL
AGTLTARAKLLAAESGLDVAPLGKIPHLRTPGLLVMDMDSTAIEIECIDEIAKLAGVGEQVSEVTERAMRGELDFTASLR
QRVGTLKGADANILKQVRDELPLMPGLVNLVRKLQAMDWHVAIASGGFTYYAEYLRDKLKLVAVAANELEIRDGKLTGEV
LGPIVDAQFKADTLVALAEKLGIPPQQTVAIGDGANDLKMMQVAGLGIAYHAKPKVYEKAQVSIRHADLIGVLCVLTGSL
KHEVR
>Mature_324_residues
SNSLTYCDLPAEISQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRELNKTRITDFQRKLGAAMVIVTAWCVEDYQVVRLA
GTLTARAKLLAAESGLDVAPLGKIPHLRTPGLLVMDMDSTAIEIECIDEIAKLAGVGEQVSEVTERAMRGELDFTASLRQ
RVGTLKGADANILKQVRDELPLMPGLVNLVRKLQAMDWHVAIASGGFTYYAEYLRDKLKLVAVAANELEIRDGKLTGEVL
GPIVDAQFKADTLVALAEKLGIPPQQTVAIGDGANDLKMMQVAGLGIAYHAKPKVYEKAQVSIRHADLIGVLCVLTGSLK
HEVR

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=185, Percent_Identity=33.5135135135135, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1790849, Length=320, Percent_Identity=76.25, Blast_Score=505, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6321647, Length=247, Percent_Identity=38.4615384615385, Blast_Score=166, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24661601, Length=214, Percent_Identity=29.4392523364486, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35298; Mature: 35166

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSLTYCDLPAEISQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRELNKTRITDFQRKL
CCCCCEEECCCHHHHHCCCCCEEECCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHH
GAAMVIVTAWCVEDYQVVRLAGTLTARAKLLAAESGLDVAPLGKIPHLRTPGLLVMDMDS
CHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCC
TAIEIECIDEIAKLAGVGEQVSEVTERAMRGELDFTASLRQRVGTLKGADANILKQVRDE
CEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
LPLMPGLVNLVRKLQAMDWHVAIASGGFTYYAEYLRDKLKLVAVAANELEIRDGKLTGEV
CCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHEEEEECCCEEEECCCCCHHH
LGPIVDAQFKADTLVALAEKLGIPPQQTVAIGDGANDLKMMQVAGLGIAYHAKPKVYEKA
HHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHEEEEECCCCEEEECCCCHHHHH
QVSIRHADLIGVLCVLTGSLKHEVR
HHEEEHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
SNSLTYCDLPAEISQWPGLPLSLSGDEVMPLDYRAGHTGWLLYGRELNKTRITDFQRKL
CCCCEEECCCHHHHHCCCCCEEECCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHH
GAAMVIVTAWCVEDYQVVRLAGTLTARAKLLAAESGLDVAPLGKIPHLRTPGLLVMDMDS
CHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCC
TAIEIECIDEIAKLAGVGEQVSEVTERAMRGELDFTASLRQRVGTLKGADANILKQVRDE
CEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
LPLMPGLVNLVRKLQAMDWHVAIASGGFTYYAEYLRDKLKLVAVAANELEIRDGKLTGEV
CCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHEEEEECCCEEEECCCCCHHH
LGPIVDAQFKADTLVALAEKLGIPPQQTVAIGDGANDLKMMQVAGLGIAYHAKPKVYEKA
HHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHEEEEECCCCEEEECCCCHHHHH
QVSIRHADLIGVLCVLTGSLKHEVR
HHEEEHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]