BacMap

Definition	Serratia proteamaculans 568 chromosome, complete genome.
Accession	NC_009832
Length	5,448,853

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The map label for this gene is hpcC [H]

Identifier: 157368872

GI number: 157368872

Start: 692462

End: 693916

Strand: Direct

Name: hpcC [H]

Synonym: Spro_0627

Alternate gene names: 157368872

Gene position: 692462-693916 (Clockwise)

Preceding gene: 157368871

Following gene: 157368873

Centisome position: 12.71

GC content: 60.55

Gene sequence:

>1455_bases
ATGAAAACCATCAACCATTGGATTAACGGTAAAAACGTAGCCAGCAAAGAGTACTTCACCACCACCAACCCGGCCAACGG
TGAGGTGCTGGCGGAAGTGGCGTCCGGCGGACAGCTGGAGATCGATCAGGCGGTGGCCGCCGCCAAGGCCGCCTTCCCGA
AATGGGCCAATACGCCAATGAAAGAGCGTGCGCGCCTGATGCGTCGCCTGGGTGAACTGATCGACGAGAACGTGCCGCAG
ATCGCCGAGATGGAAACCGCCGATACCGGCCTGCCAATCCACCAAACCAAAAACGTGCTGATCCCGCGTGCCTCGCACAA
CTTTGAGTTCTTCGCTGAGATCTGTCAGCAGATGAATGGTCGCACCTACCCGGTGGACGACAAGATGCTCAACTACACGC
TGATCCAGCCGGTCGGGGTGTGTGCGCTGGTGTCGCCGTGGAACGTGCCTTTCATGACCGCCACCTGGAAAACAGCGCCC
TGCCTGGCGCTGGGCAACACCGCGGTGCTGAAAATGTCCGAGCTGTCGCCGCTGACGGCCGATCGTCTGGGTGAACTGGC
GCTGGAAGCCGGCATTCCGGCCGGGGTGCTCAACGTGGTGCAAGGTTACGGCGCTACCGCCGGCGATGCTCTGGTGCGCC
ATAAAGACGTGCGCGCCGTGTCCTTTACCGGCGGCACCGCTACCGGTCGCCGGATTATTGAAAGCGCCGGGCTGAAGAAG
TTTTCCATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAGGATGCCGACATTGAACGTGCGCTGGATGCCGCACT
GTTCACCATTTTCTCGATCAACGGTGAACGCTGCACCGCCGGGTCGCGCATCTTTATTCAGGAGAGCATCTACCCGGAAT
TCGTCAAACGCTTCGCCGAGCGCGCCAACCGCCTGCGGGTGGGGGATCCACAGGATCCCAACACCCAGGTCGGGGCGTTG
ATCAGCCCGCAGCACTGGGAAAAAGTCTCCGGCTATATCCGCCTGGGGCTGGAAGAAGGGGCCACTCTGTTGGCCGGCGG
CCCGGATAAACCGGCCGGTCTGAGCCACGGCAACTTCCTGCGCCCGACGGTGCTGGCGGATGTCGACAACCGGATGCGCA
TTGCGCAGGAGGAGATTTTTGGGCCGGTGGCCTGCCTGCTGCCGTTCAAATCAGAAGAAGACGGCCTGCGTATGGCCAAC
GACGTGGAGTACGGCCTGGCGTCGTATATCTGGACGCAGGATGTGAGCAAGGTGCTGCGTCTGGCTCGCAATATTGAAGC
GGGCATGGTTTTCGTCAACACCCAAAATGTACGCGATCTGCGTCAGCCATTTGGCGGCGTGAAATCGTCCGGCACCGGCC
GTGAAGGCGGGGAATACAGTTTCGAAGTATTCGCCGAGATGAAGAACGTGTGTATTTCCATGGGGGATCACCCGATCCCA
CGTTGGGGCGTCTAG

Upstream 100 bases:

>100_bases
CCGACGTGCAACCGGGGGACGAAGTGGTGGTGGAGATCGAGGGCATTGGCCGTCTGGTTAACCACATCATCAGTGAAAAA
GATTACGAGGAAAGCCTGCG

Downstream 100 bases:

>100_bases
GAGGGTTATATGGGCAAATTGGCTTTAGCAGCAAAGATCACTCATGTGCCGTCAATGTATCTGTCGGAAATGCCTGGAAA
AAACCATGGTTGCCGCCAGG

Product: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: CHMS dehydrogenase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKTINHWINGKNVASKEYFTTTNPANGEVLAEVASGGQLEIDQAVAAAKAAFPKWANTPMKERARLMRRLGELIDENVPQ
IAEMETADTGLPIHQTKNVLIPRASHNFEFFAEICQQMNGRTYPVDDKMLNYTLIQPVGVCALVSPWNVPFMTATWKTAP
CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHKDVRAVSFTGGTATGRRIIESAGLKK
FSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQESIYPEFVKRFAERANRLRVGDPQDPNTQVGAL
ISPQHWEKVSGYIRLGLEEGATLLAGGPDKPAGLSHGNFLRPTVLADVDNRMRIAQEEIFGPVACLLPFKSEEDGLRMAN
DVEYGLASYIWTQDVSKVLRLARNIEAGMVFVNTQNVRDLRQPFGGVKSSGTGREGGEYSFEVFAEMKNVCISMGDHPIP
RWGV

Sequences:

>Translated_484_residues
MKTINHWINGKNVASKEYFTTTNPANGEVLAEVASGGQLEIDQAVAAAKAAFPKWANTPMKERARLMRRLGELIDENVPQ
IAEMETADTGLPIHQTKNVLIPRASHNFEFFAEICQQMNGRTYPVDDKMLNYTLIQPVGVCALVSPWNVPFMTATWKTAP
CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHKDVRAVSFTGGTATGRRIIESAGLKK
FSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQESIYPEFVKRFAERANRLRVGDPQDPNTQVGAL
ISPQHWEKVSGYIRLGLEEGATLLAGGPDKPAGLSHGNFLRPTVLADVDNRMRIAQEEIFGPVACLLPFKSEEDGLRMAN
DVEYGLASYIWTQDVSKVLRLARNIEAGMVFVNTQNVRDLRQPFGGVKSSGTGREGGEYSFEVFAEMKNVCISMGDHPIP
RWGV
>Mature_484_residues
MKTINHWINGKNVASKEYFTTTNPANGEVLAEVASGGQLEIDQAVAAAKAAFPKWANTPMKERARLMRRLGELIDENVPQ
IAEMETADTGLPIHQTKNVLIPRASHNFEFFAEICQQMNGRTYPVDDKMLNYTLIQPVGVCALVSPWNVPFMTATWKTAP
CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHKDVRAVSFTGGTATGRRIIESAGLKK
FSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQESIYPEFVKRFAERANRLRVGDPQDPNTQVGAL
ISPQHWEKVSGYIRLGLEEGATLLAGGPDKPAGLSHGNFLRPTVLADVDNRMRIAQEEIFGPVACLLPFKSEEDGLRMAN
DVEYGLASYIWTQDVSKVLRLARNIEAGMVFVNTQNVRDLRQPFGGVKSSGTGREGGEYSFEVFAEMKNVCISMGDHPIP
RWGV

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=476, Percent_Identity=41.5966386554622, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI25777730, Length=476, Percent_Identity=41.5966386554622, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI25777732, Length=476, Percent_Identity=41.8067226890756, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI153266822, Length=478, Percent_Identity=39.9581589958159, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI25777724, Length=477, Percent_Identity=40.8805031446541, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI21361176, Length=476, Percent_Identity=39.7058823529412, Blast_Score=353, Evalue=2e-97,
Organism=Homo sapiens, GI238814322, Length=481, Percent_Identity=39.7089397089397, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI115387104, Length=459, Percent_Identity=38.9978213507625, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI25777728, Length=417, Percent_Identity=41.726618705036, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI21614513, Length=464, Percent_Identity=40.301724137931, Blast_Score=336, Evalue=3e-92,
Organism=Homo sapiens, GI25952152, Length=476, Percent_Identity=35.7142857142857, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI25777726, Length=474, Percent_Identity=37.3417721518987, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI301500698, Length=481, Percent_Identity=35.5509355509356, Blast_Score=281, Evalue=9e-76,
Organism=Homo sapiens, GI4507229, Length=475, Percent_Identity=35.5789473684211, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI25777721, Length=488, Percent_Identity=34.4262295081967, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI11095441, Length=478, Percent_Identity=30.5439330543933, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI310128093, Length=475, Percent_Identity=28.2105263157895, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI188035924, Length=493, Percent_Identity=27.5862068965517, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI310128103, Length=475, Percent_Identity=28, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI310128091, Length=475, Percent_Identity=27.1578947368421, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=31.306990881459, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI223972651, Length=460, Percent_Identity=28.0434782608696, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI238859541, Length=483, Percent_Identity=25.6728778467909, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI25777736, Length=483, Percent_Identity=25.6728778467909, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI25777734, Length=483, Percent_Identity=25.6728778467909, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI310128097, Length=261, Percent_Identity=32.5670498084291, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI206597441, Length=447, Percent_Identity=27.0693512304251, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI206597439, Length=447, Percent_Identity=27.0693512304251, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI22907049, Length=447, Percent_Identity=27.0693512304251, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557303, Length=341, Percent_Identity=29.0322580645161, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI73466520, Length=341, Percent_Identity=29.0322580645161, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=29.746835443038, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI223972653, Length=458, Percent_Identity=25.1091703056769, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI73695881, Length=343, Percent_Identity=25.9475218658892, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI73695879, Length=343, Percent_Identity=25.9475218658892, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=26.6272189349112, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI4502043, Length=338, Percent_Identity=26.6272189349112, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI238814371, Length=338, Percent_Identity=26.6272189349112, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI310128087, Length=292, Percent_Identity=24.6575342465753, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI310128101, Length=236, Percent_Identity=23.3050847457627, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI310128099, Length=236, Percent_Identity=23.3050847457627, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787558, Length=476, Percent_Identity=39.7058823529412, Blast_Score=351, Evalue=5e-98,
Organism=Escherichia coli, GI1786504, Length=474, Percent_Identity=39.0295358649789, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1789015, Length=474, Percent_Identity=37.9746835443038, Blast_Score=332, Evalue=5e-92,
Organism=Escherichia coli, GI87082295, Length=488, Percent_Identity=37.7049180327869, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI87081896, Length=468, Percent_Identity=35.6837606837607, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1787715, Length=471, Percent_Identity=38.8535031847134, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI1787684, Length=472, Percent_Identity=31.1440677966102, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87081926, Length=457, Percent_Identity=31.5098468271335, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788042, Length=470, Percent_Identity=28.7234042553192, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1787250, Length=461, Percent_Identity=25.8134490238612, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1787653, Length=297, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562198, Length=479, Percent_Identity=40.2922755741127, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25144435, Length=476, Percent_Identity=40.1260504201681, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI133930964, Length=481, Percent_Identity=38.6694386694387, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI25143876, Length=483, Percent_Identity=37.2670807453416, Blast_Score=338, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI25143874, Length=483, Percent_Identity=37.2670807453416, Blast_Score=337, Evalue=8e-93,
Organism=Caenorhabditis elegans, GI32564736, Length=416, Percent_Identity=40.1442307692308, Blast_Score=329, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17551164, Length=487, Percent_Identity=37.9876796714579, Blast_Score=327, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI71995606, Length=482, Percent_Identity=34.6473029045643, Blast_Score=295, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI71995613, Length=418, Percent_Identity=34.9282296650718, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17534119, Length=469, Percent_Identity=33.0490405117271, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI71986308, Length=440, Percent_Identity=32.7272727272727, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI115534176, Length=484, Percent_Identity=25.8264462809917, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32566756, Length=439, Percent_Identity=28.4738041002278, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI25146391, Length=439, Percent_Identity=28.4738041002278, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI25146394, Length=439, Percent_Identity=28.4738041002278, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17534447, Length=456, Percent_Identity=26.0964912280702, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17564084, Length=444, Percent_Identity=27.7027027027027, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115532534, Length=338, Percent_Identity=26.3313609467456, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=415, Percent_Identity=26.0240963855422, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=296, Percent_Identity=25.3378378378378, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324950, Length=470, Percent_Identity=39.1489361702128, Blast_Score=340, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6320917, Length=480, Percent_Identity=38.5416666666667, Blast_Score=337, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6323822, Length=463, Percent_Identity=38.0129589632829, Blast_Score=326, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6325196, Length=477, Percent_Identity=37.9454926624738, Blast_Score=325, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6323821, Length=463, Percent_Identity=36.9330453563715, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6319478, Length=479, Percent_Identity=35.0730688935282, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321828, Length=499, Percent_Identity=26.0521042084168, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321826, Length=501, Percent_Identity=26.3473053892216, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323757, Length=355, Percent_Identity=26.4788732394366, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20129399, Length=476, Percent_Identity=43.6974789915966, Blast_Score=381, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24585660, Length=478, Percent_Identity=38.4937238493724, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24650465, Length=466, Percent_Identity=40.7725321888412, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI281362580, Length=475, Percent_Identity=36.2105263157895, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI62472918, Length=475, Percent_Identity=36.2105263157895, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI62472926, Length=475, Percent_Identity=36.2105263157895, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI62472936, Length=475, Percent_Identity=36.2105263157895, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI21356737, Length=475, Percent_Identity=36.2105263157895, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24638878, Length=438, Percent_Identity=31.9634703196347, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24638876, Length=438, Percent_Identity=31.9634703196347, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24666674, Length=473, Percent_Identity=26.4270613107822, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24668425, Length=504, Percent_Identity=25.9920634920635, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24668417, Length=504, Percent_Identity=25.9920634920635, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24668413, Length=504, Percent_Identity=25.9920634920635, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360303, Length=352, Percent_Identity=26.4204545454545, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360299, Length=352, Percent_Identity=26.9886363636364, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360297, Length=352, Percent_Identity=26.9886363636364, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360295, Length=352, Percent_Identity=26.9886363636364, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586250, Length=352, Percent_Identity=26.9886363636364, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45552499, Length=353, Percent_Identity=26.628895184136, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360301, Length=351, Percent_Identity=26.7806267806268, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571806, Length=490, Percent_Identity=23.0612244897959, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571802, Length=490, Percent_Identity=23.0612244897959, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571800, Length=490, Percent_Identity=23.0612244897959, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571798, Length=490, Percent_Identity=23.0612244897959, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571796, Length=490, Percent_Identity=23.0612244897959, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571794, Length=490, Percent_Identity=23.0612244897959, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28574525, Length=462, Percent_Identity=21.8614718614719, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR011985 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 52828; Mature: 52828

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTINHWINGKNVASKEYFTTTNPANGEVLAEVASGGQLEIDQAVAAAKAAFPKWANTPM
CCCHHHHCCCCCCCCCCEEECCCCCCCHHHEEECCCCCEEHHHHHHHHHHCCCCCCCCCH
KERARLMRRLGELIDENVPQIAEMETADTGLPIHQTKNVLIPRASHNFEFFAEICQQMNG
HHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCC
RTYPVDDKMLNYTLIQPVGVCALVSPWNVPFMTATWKTAPCLALGNTAVLKMSELSPLTA
CCCCCCCHHHCEEEECCCCEEEEECCCCCCEEEEECCCCCEEEECCCEEEEECCCCCCCH
DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHKDVRAVSFTGGTATGRRIIESAGLKK
HHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEE
FSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQESIYPEFVKRFAE
EHHHCCCCCCEEEEECCCHHHHHHHHHHHHEECCCCEECCCCEEEEECCCCHHHHHHHHH
RANRLRVGDPQDPNTQVGALISPQHWEKVSGYIRLGLEEGATLLAGGPDKPAGLSHGNFL
HHCCEECCCCCCCCCCCCEEECCHHHHHHCCEEEEECCCCCEEEECCCCCCCCCCCCCCC
RPTVLADVDNRMRIAQEEIFGPVACLLPFKSEEDGLRMANDVEYGLASYIWTQDVSKVLR
CCHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LARNIEAGMVFVNTQNVRDLRQPFGGVKSSGTGREGGEYSFEVFAEMKNVCISMGDHPIP
HHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
RWGV
CCCC
>Mature Secondary Structure
MKTINHWINGKNVASKEYFTTTNPANGEVLAEVASGGQLEIDQAVAAAKAAFPKWANTPM
CCCHHHHCCCCCCCCCCEEECCCCCCCHHHEEECCCCCEEHHHHHHHHHHCCCCCCCCCH
KERARLMRRLGELIDENVPQIAEMETADTGLPIHQTKNVLIPRASHNFEFFAEICQQMNG
HHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCC
RTYPVDDKMLNYTLIQPVGVCALVSPWNVPFMTATWKTAPCLALGNTAVLKMSELSPLTA
CCCCCCCHHHCEEEECCCCEEEEECCCCCCEEEEECCCCCEEEECCCEEEEECCCCCCCH
DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHKDVRAVSFTGGTATGRRIIESAGLKK
HHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCEE
FSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQESIYPEFVKRFAE
EHHHCCCCCCEEEEECCCHHHHHHHHHHHHEECCCCEECCCCEEEEECCCCHHHHHHHHH
RANRLRVGDPQDPNTQVGALISPQHWEKVSGYIRLGLEEGATLLAGGPDKPAGLSHGNFL
HHCCEECCCCCCCCCCCCEEECCHHHHHHCCEEEEECCCCCEEEECCCCCCCCCCCCCCC
RPTVLADVDNRMRIAQEEIFGPVACLLPFKSEEDGLRMANDVEYGLASYIWTQDVSKVLR
CCHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LARNIEAGMVFVNTQNVRDLRQPFGGVKSSGTGREGGEYSFEVFAEMKNVCISMGDHPIP
HHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
RWGV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]