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The map label for this gene is frdC

Identifier: 157368664

GI number: 157368664

Start: 463850

End: 464242

Strand: Reverse

Name: frdC

Synonym: Spro_0417

Alternate gene names: 157368664

Gene position: 464242-463850 (Counterclockwise)

Preceding gene: 157368665

Following gene: 157368663

Centisome position: 8.52

GC content: 55.47

Gene sequence:

>393_bases
ATGACAACACAACGTAAGCCCTATGTGCGCACCATGACGCCGACCTGGTGGCAAAAGCTCGGCTTCTACCGTTTCTATAT
GCTGCGTGAAGGCACCTCGGTGCCGGCGGTCTGGTTCAGTATTGTGCTGATCTACGGCGTCTTTGCGCTAAAAGGCGGAG
TAGACAGTTGGGCCGGTTTCGTCGGTTTTCTGCAAAACCCGCTGGTGCTGCTGATTAACTTCGTCGCACTACTGGCCGCA
CTGCTGCATACCAAGACCTGGTTCGATTTGGCGCCGAAAGCCGCCAACATTGTGGTTAACAGCGAGAAAATGGGCCCGGG
GCCAATAGTGAAAACGCTATGGGCGGTGACTGTAGTTGCCAGCGTGGTCATTCTGGCCGTGGCCTTGGTGTAA

Upstream 100 bases:

>100_bases
GCACGTCGACCCGGCCGCTGCCATCCAGCAGGGCAAGGTGGAAAGTGCCAAAGACTTCATGATCGCCATGCTGAAGCCGC
AATAAGGGAGATAAACAGCA

Downstream 100 bases:

>100_bases
TCCGGAGGAAACATGATAAATCAAGCACCTAAACGCTCAGACGAACCGGTTTTCTGGGGATTATTCGGCGCCGGCGGCAT
GTGGGGAGCCATCATCGCCC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: Fumarate reductase 15 kDa hydrophobic protein

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTTQRKPYVRTMTPTWWQKLGFYRFYMLREGTSVPAVWFSIVLIYGVFALKGGVDSWAGFVGFLQNPLVLLINFVALLAA
LLHTKTWFDLAPKAANIVVNSEKMGPGPIVKTLWAVTVVASVVILAVALV

Sequences:

>Translated_130_residues
MTTQRKPYVRTMTPTWWQKLGFYRFYMLREGTSVPAVWFSIVLIYGVFALKGGVDSWAGFVGFLQNPLVLLINFVALLAA
LLHTKTWFDLAPKAANIVVNSEKMGPGPIVKTLWAVTVVASVVILAVALV
>Mature_129_residues
TTQRKPYVRTMTPTWWQKLGFYRFYMLREGTSVPAVWFSIVLIYGVFALKGGVDSWAGFVGFLQNPLVLLINFVALLAAL
LHTKTWFDLAPKAANIVVNSEKMGPGPIVKTLWAVTVVASVVILAVALV

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family

Homologues:

Organism=Escherichia coli, GI1790595, Length=129, Percent_Identity=75.1937984496124, Blast_Score=205, Evalue=7e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDC_SERP5 (A8G8T5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476653.1
- ProteinModelPortal:   A8G8T5
- SMR:   A8G8T5
- STRING:   A8G8T5
- GeneID:   5602593
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0417
- eggNOG:   COG3029
- HOGENOM:   HBG554089
- OMA:   KMGPEPV
- ProtClustDB:   PRK04987
- BioCyc:   SPRO399741:SPRO_0417-MONOMER
- HAMAP:   MF_00708
- InterPro:   IPR003510
- ProDom:   PD015900

Pfam domain/function: PF02300 Fumarate_red_C

EC number: 1.3.99.1

Molecular weight: Translated: 14415; Mature: 14284

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x221931ac)-; HASH(0x221d96c8)-; HASH(0x20bc7d20)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQRKPYVRTMTPTWWQKLGFYRFYMLREGTSVPAVWFSIVLIYGVFALKGGVDSWAGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
VGFLQNPLVLLINFVALLAALLHTKTWFDLAPKAANIVVNSEKMGPGPIVKTLWAVTVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHHHHHHHHH
SVVILAVALV
HHHHHHHHCH
>Mature Secondary Structure 
TTQRKPYVRTMTPTWWQKLGFYRFYMLREGTSVPAVWFSIVLIYGVFALKGGVDSWAGF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
VGFLQNPLVLLINFVALLAALLHTKTWFDLAPKAANIVVNSEKMGPGPIVKTLWAVTVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHHHHHHHHH
SVVILAVALV
HHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA