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The map label for this gene is frdD

Identifier: 157368663

GI number: 157368663

Start: 463478

End: 463837

Strand: Reverse

Name: frdD

Synonym: Spro_0416

Alternate gene names: 157368663

Gene position: 463837-463478 (Counterclockwise)

Preceding gene: 157368664

Following gene: 157368658

Centisome position: 8.51

GC content: 57.22

Gene sequence:

>360_bases
ATGATAAATCAAGCACCTAAACGCTCAGACGAACCGGTTTTCTGGGGATTATTCGGCGCCGGCGGCATGTGGGGAGCCAT
CATCGCCCCCGCCATAGTGCTGCTGGTCGGCATTCTGCTGCCATTGGGGTTATTCCCAGGCGATGCGCTGGGCTATGACC
GCATACTGGCCTTCTGCCAGAGCCTGATCGGCCGCCTGTTCCTGTTGCTGATGATTATCCTGCCGCTGTGGTGCGGTTTA
CACCGTATCCACCATGCGATGCACGATTTGAAAATCCATGTGCCGGCCGGCAAATGGGTCTTCTACGGCCTGGCTGCCAT
CCTCAGCGTAGTGACCGTGATCGGCGTAGTGACTCTGTAA

Upstream 100 bases:

>100_bases
GAAAATGGGCCCGGGGCCAATAGTGAAAACGCTATGGGCGGTGACTGTAGTTGCCAGCGTGGTCATTCTGGCCGTGGCCT
TGGTGTAATCCGGAGGAAAC

Downstream 100 bases:

>100_bases
ATCTCTTCTGGCGGCCACTTCCGTTGGCCGCCTTTTACATCTCTTAATGACTGCTGAACTTCAGCCCGAGTATGCCGACA
ACGATCAGGCACAGGCTGAG

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: Fumarate reductase 13 kDa hydrophobic protein

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MINQAPKRSDEPVFWGLFGAGGMWGAIIAPAIVLLVGILLPLGLFPGDALGYDRILAFCQSLIGRLFLLLMIILPLWCGL
HRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTVIGVVTL

Sequences:

>Translated_119_residues
MINQAPKRSDEPVFWGLFGAGGMWGAIIAPAIVLLVGILLPLGLFPGDALGYDRILAFCQSLIGRLFLLLMIILPLWCGL
HRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTVIGVVTL
>Mature_119_residues
MINQAPKRSDEPVFWGLFGAGGMWGAIIAPAIVLLVGILLPLGLFPGDALGYDRILAFCQSLIGRLFLLLMIILPLWCGL
HRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTVIGVVTL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family

Homologues:

Organism=Escherichia coli, GI1790594, Length=119, Percent_Identity=84.8739495798319, Blast_Score=208, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDD_SERP5 (A8G8T4)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476652.1
- ProteinModelPortal:   A8G8T4
- SMR:   A8G8T4
- STRING:   A8G8T4
- GeneID:   5602592
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0416
- eggNOG:   COG3080
- HOGENOM:   HBG297136
- OMA:   HRIHHGM
- ProtClustDB:   PRK05470
- BioCyc:   SPRO399741:SPRO_0416-MONOMER
- HAMAP:   MF_00709
- InterPro:   IPR003418
- ProDom:   PD015693

Pfam domain/function: PF02313 Fumarate_red_D

EC number: 1.3.99.1

Molecular weight: Translated: 12921; Mature: 12921

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21504718)-; HASH(0x2223e838)-; HASH(0x21fa5510)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQAPKRSDEPVFWGLFGAGGMWGAIIAPAIVLLVGILLPLGLFPGDALGYDRILAFCQ
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
SLIGRLFLLLMIILPLWCGLHRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTVIGVVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MINQAPKRSDEPVFWGLFGAGGMWGAIIAPAIVLLVGILLPLGLFPGDALGYDRILAFCQ
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
SLIGRLFLLLMIILPLWCGLHRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTVIGVVTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA