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The map label for this gene is dppC [H]

Identifier: 157368389

GI number: 157368389

Start: 151246

End: 152148

Strand: Direct

Name: dppC [H]

Synonym: Spro_0140

Alternate gene names: 157368389

Gene position: 151246-152148 (Clockwise)

Preceding gene: 157368388

Following gene: 157368390

Centisome position: 2.78

GC content: 58.8

Gene sequence:

>903_bases
ATGTCTCAAGTCACTGAGTCTGTAGTTAAAGGTGCGCCGAAGCCGATGAGCCCGTTCCAGGAGTTCTGGCACTATTTCAA
GCGCAATAAAGGGGCCGTTGTCGGCCTGGTGTATATCGTTCTGATGTTTGTGATTGCCATCGGTGCCGGGGTGCTGGCAC
CGCATGCGCCGGCGGATCAGTTCCGCGATGCGCTGCTCAAGCCACCGGTCTGGCAGGAAGGCGGCAGTTGGCAATATCTG
CTGGGTACTGATGACGTTGGCCGCGATGTGCTGTCGCGCCTGATGTATGGCGCCCGACTGTCACTGTTGGTTGGCTGCCT
GGTGGTGGTGCTGTCGCTGATCATGGGCGTGGTGCTGGGCCTGCTGGCCGGATACTTTGGCGGCGTGGTGGATGCCATCA
TCATGCGTATCGTCGACATTATGCTGGCGTTGCCCAGCCTGCTGTTGGCGTTGGTATTGGTGGCGATTTTCGGTCCGTCG
ATCGTCAATGCTTCACTGGCGTTAACCTTTGTCGCCTTGCCGCACTATGTGCGTCTGACCCGTGCTGCGGTATTGGTGGA
AGTGAACCGCGACTACGTCACCGCTTCACGCGTGGCGGGGGCCGGTGCGATGCGCCAAATGTTTATCAATATCCTGCCAA
ACTGCCTGGCGCCGCTGATCGTTCAGGCTTCTCTGGGTTTCTCGAACGCTATCCTGGATATGGCCGCTCTCGGCTTCCTG
GGTATGGGTGCACAACCGCCAACGCCGGAGTGGGGCACCATGCTCTCCGACGTATTGCAGTTCGCACAAAGCGCCTGGTG
GGTAGTAACCTTCCCTGGCGTGGCGATCCTGCTGACGGTGCTTGCATTTAACCTGATGGGGGACGGCTTGCGTGATGCTC
TCGACCCCAAACTCAAGCAGTAA

Upstream 100 bases:

>100_bases
TGCTGGTCGCCTGTATGATTATTCTGGTTAACCTGCTGGTAGACGTGCTCTACGGCGTGGTCAACCCGCGTATTCGCCAC
AAGAAATAAGGGGCGCTCTA

Downstream 100 bases:

>100_bases
AGAGGACGAGAGAGATGGCGTTATTAAATGTAGACAAGCTTTCGGTGCACTTCGGTGACGAAGGCACCCCTTTCCGCGCG
GTAGACCGTATCAGTTACAG

Product: dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSQVTESVVKGAPKPMSPFQEFWHYFKRNKGAVVGLVYIVLMFVIAIGAGVLAPHAPADQFRDALLKPPVWQEGGSWQYL
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVVLGLLAGYFGGVVDAIIMRIVDIMLALPSLLLALVLVAIFGPS
IVNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_300_residues
MSQVTESVVKGAPKPMSPFQEFWHYFKRNKGAVVGLVYIVLMFVIAIGAGVLAPHAPADQFRDALLKPPVWQEGGSWQYL
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVVLGLLAGYFGGVVDAIIMRIVDIMLALPSLLLALVLVAIFGPS
IVNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
>Mature_299_residues
SQVTESVVKGAPKPMSPFQEFWHYFKRNKGAVVGLVYIVLMFVIAIGAGVLAPHAPADQFRDALLKPPVWQEGGSWQYLL
GTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVVLGLLAGYFGGVVDAIIMRIVDIMLALPSLLLALVLVAIFGPSI
VNASLALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLG
MGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=89, Blast_Score=459, Evalue=1e-131,
Organism=Escherichia coli, GI1787054, Length=283, Percent_Identity=40.9893992932862, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=47.5471698113208, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1787549, Length=286, Percent_Identity=40.9090909090909, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1789889, Length=222, Percent_Identity=38.7387387387387, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=33.8078291814947, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788505, Length=221, Percent_Identity=32.579185520362, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32178; Mature: 32047

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVTESVVKGAPKPMSPFQEFWHYFKRNKGAVVGLVYIVLMFVIAIGAGVLAPHAPADQ
CCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHHH
FRDALLKPPVWQEGGSWQYLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVVLG
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGYFGGVVDAIIMRIVDIMLALPSLLLALVLVAIFGPSIVNASLALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQVTESVVKGAPKPMSPFQEFWHYFKRNKGAVVGLVYIVLMFVIAIGAGVLAPHAPADQ
CHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHHH
FRDALLKPPVWQEGGSWQYLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVVLG
HHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGYFGGVVDAIIMRIVDIMLALPSLLLALVLVAIFGPSIVNASLALTFVALPHYVRLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFL
HHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGVAILLTVLAFNLMGDGLRDALDPKLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]