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The map label for this gene is dppB [H]

Identifier: 157368388

GI number: 157368388

Start: 150179

End: 151234

Strand: Direct

Name: dppB [H]

Synonym: Spro_0139

Alternate gene names: 157368388

Gene position: 150179-151234 (Clockwise)

Preceding gene: 157368387

Following gene: 157368389

Centisome position: 2.76

GC content: 57.67

Gene sequence:

>1056_bases
ATGAGCTGCCGGGCATTGATACAGAGAGTTCGGGATATGTTGCAGTTCATACTCCGACGTTTGGGGTTAGTTATCCCAAC
GTTTATCGGCATCACTTTGCTGACTTTTGCATTCGTCCATATGATCCCCGGCGACCCGGTGACCATCATGGCCGGGGAAC
GCGGGATCTCCGCAGAACGCCATGCACACCTGATGGCGGAAATGGGGCTGGATAAACCGCTCTATCAACAATATTTCACT
TACGTATCCAACGTGTTGCATGGCGATCTGGGTACCTCGCTTAAAAGCCGTATCTCCGTTTGGGAAGAGTTCGTTCCGCG
CTTCAAGGCTACGCTGGAGTTGGGGCTCTGCGCGATGATTTTCGCCGTGCTGGTGGGCATTCCGGTTGGGGTGCTGGCGG
CGGTCAGGCGAGGCTCAATATTCGATCATACCGCGGTGGGCATCTCACTGACCGGCTATTCGATGCCGATTTTCTGGTGG
GGCATGATGTTGATCATGCTGGTCTCGGTGCAGCTCAACCTGACGCCGGTATCGGGACGGGTCAGCGATACGGTGTTCCT
TGACGATAGCCTGCCGTTGACCGGCTTTATGCTGATCGACACCCTGATCTGGGGCGAACCGGGCGACTTCGCTGACGCCG
TGATGCATATGATCCTGCCGGCCATCGTGTTGGGCACCATCCCGCTGGCGGTCATTGTGCGTATGACGCGCTCCTCGATG
CTGGAAGTGCTGGGCGAAGATTATATCCGTACCGCGCGCGCCAAGGGCGTGAGCCGTATGCGGGTGATTGTGGTGCATGC
GCTGCGTAACGCCTTGCTGCCGGTCGTGACGGTGATCGGCCTGCAGGTCGGCACCATGTTGGCCGGTGCGATCCTGACCG
AAACCATCTTCTCCTGGCCGGGCCTGGGGCGTTGGCTGATGGACGCATTGCAACGTCGCGACTATCCGGTTGTTCAGGGC
GGCGTATTGCTGGTCGCCTGTATGATTATTCTGGTTAACCTGCTGGTAGACGTGCTCTACGGCGTGGTCAACCCGCGTAT
TCGCCACAAGAAATAA

Upstream 100 bases:

>100_bases
TACCGGTTAATACCACGCCCCTCTCTTTAAGGGAGGGGTGGGGTTGCCCGTAGGCAGAGAAGCACCAGAGGTGTGTGAGC
TTTAATAAGCCTGGCGGACG

Downstream 100 bases:

>100_bases
GGGGCGCTCTAATGTCTCAAGTCACTGAGTCTGTAGTTAAAGGTGCGCCGAAGCCGATGAGCCCGTTCCAGGAGTTCTGG
CACTATTTCAAGCGCAATAA

Product: dipeptide transporter permease DppB

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSCRALIQRVRDMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAHLMAEMGLDKPLYQQYFT
YVSNVLHGDLGTSLKSRISVWEEFVPRFKATLELGLCAMIFAVLVGIPVGVLAAVRRGSIFDHTAVGISLTGYSMPIFWW
GMMLIMLVSVQLNLTPVSGRVSDTVFLDDSLPLTGFMLIDTLIWGEPGDFADAVMHMILPAIVLGTIPLAVIVRMTRSSM
LEVLGEDYIRTARAKGVSRMRVIVVHALRNALLPVVTVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQRRDYPVVQG
GVLLVACMIILVNLLVDVLYGVVNPRIRHKK

Sequences:

>Translated_351_residues
MSCRALIQRVRDMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAHLMAEMGLDKPLYQQYFT
YVSNVLHGDLGTSLKSRISVWEEFVPRFKATLELGLCAMIFAVLVGIPVGVLAAVRRGSIFDHTAVGISLTGYSMPIFWW
GMMLIMLVSVQLNLTPVSGRVSDTVFLDDSLPLTGFMLIDTLIWGEPGDFADAVMHMILPAIVLGTIPLAVIVRMTRSSM
LEVLGEDYIRTARAKGVSRMRVIVVHALRNALLPVVTVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQRRDYPVVQG
GVLLVACMIILVNLLVDVLYGVVNPRIRHKK
>Mature_350_residues
SCRALIQRVRDMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAERHAHLMAEMGLDKPLYQQYFTY
VSNVLHGDLGTSLKSRISVWEEFVPRFKATLELGLCAMIFAVLVGIPVGVLAAVRRGSIFDHTAVGISLTGYSMPIFWWG
MMLIMLVSVQLNLTPVSGRVSDTVFLDDSLPLTGFMLIDTLIWGEPGDFADAVMHMILPAIVLGTIPLAVIVRMTRSSML
EVLGEDYIRTARAKGVSRMRVIVVHALRNALLPVVTVIGLQVGTMLAGAILTETIFSWPGLGRWLMDALQRRDYPVVQGG
VLLVACMIILVNLLVDVLYGVVNPRIRHKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=88.2005899705015, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=42.603550295858, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=44.3768996960486, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1787550, Length=281, Percent_Identity=37.7224199288256, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=35.207100591716, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=32.258064516129, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1788504, Length=378, Percent_Identity=29.1005291005291, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38751; Mature: 38620

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCRALIQRVRDMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
HAHLMAEMGLDKPLYQQYFTYVSNVLHGDLGTSLKSRISVWEEFVPRFKATLELGLCAMI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAVLVGIPVGVLAAVRRGSIFDHTAVGISLTGYSMPIFWWGMMLIMLVSVQLNLTPVSGR
HHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHCEEECCCC
VSDTVFLDDSLPLTGFMLIDTLIWGEPGDFADAVMHMILPAIVLGTIPLAVIVRMTRSSM
CCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVLGEDYIRTARAKGVSRMRVIVVHALRNALLPVVTVIGLQVGTMLAGAILTETIFSWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLGRWLMDALQRRDYPVVQGGVLLVACMIILVNLLVDVLYGVVNPRIRHKK
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SCRALIQRVRDMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVTIMAGERGISAER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH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CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]