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The map label for this gene is siaT [H]

Identifier: 157368371

GI number: 157368371

Start: 130011

End: 131882

Strand: Reverse

Name: siaT [H]

Synonym: Spro_0122

Alternate gene names: 157368371

Gene position: 131882-130011 (Counterclockwise)

Preceding gene: 157368372

Following gene: 157368370

Centisome position: 2.42

GC content: 61.86

Gene sequence:

>1872_bases
ATGACCCTTCCTGTAACCCTTGAAATGAGCGTAAAAAAAGTGGCCATCCTGACGCAGTTAAGCCGCGGTCTGACCCGCTT
TACCGCCTGGGGTGGAGCACTGGCGCTGCTGATCAACGTGGTGGTGGTATTCGCCTCGGTGATTTGGCGCTACGCGCTGC
ACAGCCCGATTGAATGGGCGGAAGAAGTGGCGCGCGCGCTGATGGTAACGCTGGTGTTCTTCGGCGTCGCCACCTCCACC
GGGCGTGGCCGACACATCGGCGTCGATCTGTTCCTGCGCTGGCTGCCCGCGGTAGCCCGGCCCTACGTGGTGCATGCCAG
CCGTTGGGTGCTGGTACTGGTGGCGCTGGGCCTGACGGTGTCCAGCTTCAGCCTGGTGGGTATTTCACTGCCACAGACCA
CCGAACACGGCCTGCCACAGGCGATCTTCGTGGTTCCGGTGTTCATCGGCGCGGCAGTGATGCTGGTCAGCGCGCTCGAT
CACGCCTGCCAGGCACCGTTGAAAGTGGTGTTAATCAGCGCCGCCGCCGTCGCTCTTCTGGGCGGCGCTGGCTACCTCAG
CCTGCATGCCCCGCTGGGGTTCAGCTCGCTGCCCGCCGCGCTGATGCTGGCCTGCTTTATCCTGGGCATCATCTCCGGCG
TGCCAATCGCCTTTACCCTGGGCATGTCGGCTATGGTGTTCTTTCTTAGCGATCCATCGCTGCCATTCGTGTTCTTTGCC
CAGCAGGTGACCGCCGGCGTCGATCATTTTGTGCTGCTGGCCATTCCGTTCTTTCTGCTGGCTGGTGCGGTGATGGAGGT
CAACGGCATGTCGTCACGGCTGGTTGAGCTGATCGTGCGCGGCATGGGGCGTTATCGCGGTGGCCTGAATATGACCACGA
TTGTATCGATGGCCTTCTTCTCGGGTATTTCCGGCTCCAAACTGGCAGACGTCGCCACGGTCGGCGGCGTGCTGATGCCC
GCGGTACGCCGGGCACGCCAACCGGCCGCAGAGTCTGCCGGGGTGTTCGCCGCCTCGGCGATCATGGCGGAAACCATCCC
CCCCTGCGTCAATCTGATCGTGATGGGCTTTATTGCCAATATTTCGATTGGCGCACTGTTTATCGCCGGCCTGATCCCAG
CGCTGTGCCTGCTGGTGTTGCTGCTGATTGCCGCCGTGATCTTCGGCAAGCGCATCAACGTCGATGACGCCTACCCGGTG
CGAATGCCAACCCGCCAACTGCTGATCGGTGCCGCCGTCGGGCTGGTGATGATTTTGATGATCGGCAAGGGCGTGGTGGC
CGGTATCGCCACCTCCACCGAGATTTCCGCCTTTGCCGTGGTTTACGCCATCGTGGTCGGTCGGCTGGCCTTTGGGGAAC
TGACCCTGAAAGCCACGGTGAAGTTGTTCGTCGACACCGCAGCGCTGTCCGGCATGCTGTTGTTTATCGTCGCCTGCGCC
ACCAGTTTGTCCTTCGCTCTGACCATCGAGATGATCCCGCAGCAGTGCGCGCAACTGTTGGTCGCCATCGGCGCGGACTA
CGGCCCGTGGCTGTTTCTGCTGCTGTCGATTGTCATCCTGATTATTTTCGGCGCGGTGCTGGAGGGGGCTCCGGCGCTGA
TTATCTTTGCCCCCATCCTGGTCCCTATCGCCACCCAGCTCGGCTTCAACCCGCTGCACTACGCCATTGTGATGATTCTG
GCGATGGGCTTCGGCCTGTTTTCCCCGCCGATCGGCCTGGGCCTGTACACCACCTGCGCCATTTGCGGCGTACCGATGCA
GGACGTGATTAAACCTATGGCCAAGTACCTGCTGATCATCCTGCTCGGCATCATTGTTATCGCGCTGTTCCCGGCGCTCA
CCACCTGGCTGCCCACGCGGCTGGGCTACTGA

Upstream 100 bases:

>100_bases
ACAGGCGGCATTTAGCGGGAAATACCCACAGGCCAAAGCGGTGCTGGATGCCATTCATGCCACAGCGCAGCCCTAACGCA
CGCCTGGCGGAGGATTTGCT

Downstream 100 bases:

>100_bases
TTTTCTCAAGCAAGGAGTCATACCATGTTCTCTGATTTAACCAACAAACGCGTGTTGATCACCGGTTCCACCGCCGGTAT
CGGATTGGCAACCGCCGCCC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTLPVTLEMSVKKVAILTQLSRGLTRFTAWGGALALLINVVVVFASVIWRYALHSPIEWAEEVARALMVTLVFFGVATST
GRGRHIGVDLFLRWLPAVARPYVVHASRWVLVLVALGLTVSSFSLVGISLPQTTEHGLPQAIFVVPVFIGAAVMLVSALD
HACQAPLKVVLISAAAVALLGGAGYLSLHAPLGFSSLPAALMLACFILGIISGVPIAFTLGMSAMVFFLSDPSLPFVFFA
QQVTAGVDHFVLLAIPFFLLAGAVMEVNGMSSRLVELIVRGMGRYRGGLNMTTIVSMAFFSGISGSKLADVATVGGVLMP
AVRRARQPAAESAGVFAASAIMAETIPPCVNLIVMGFIANISIGALFIAGLIPALCLLVLLLIAAVIFGKRINVDDAYPV
RMPTRQLLIGAAVGLVMILMIGKGVVAGIATSTEISAFAVVYAIVVGRLAFGELTLKATVKLFVDTAALSGMLLFIVACA
TSLSFALTIEMIPQQCAQLLVAIGADYGPWLFLLLSIVILIIFGAVLEGAPALIIFAPILVPIATQLGFNPLHYAIVMIL
AMGFGLFSPPIGLGLYTTCAICGVPMQDVIKPMAKYLLIILLGIIVIALFPALTTWLPTRLGY

Sequences:

>Translated_623_residues
MTLPVTLEMSVKKVAILTQLSRGLTRFTAWGGALALLINVVVVFASVIWRYALHSPIEWAEEVARALMVTLVFFGVATST
GRGRHIGVDLFLRWLPAVARPYVVHASRWVLVLVALGLTVSSFSLVGISLPQTTEHGLPQAIFVVPVFIGAAVMLVSALD
HACQAPLKVVLISAAAVALLGGAGYLSLHAPLGFSSLPAALMLACFILGIISGVPIAFTLGMSAMVFFLSDPSLPFVFFA
QQVTAGVDHFVLLAIPFFLLAGAVMEVNGMSSRLVELIVRGMGRYRGGLNMTTIVSMAFFSGISGSKLADVATVGGVLMP
AVRRARQPAAESAGVFAASAIMAETIPPCVNLIVMGFIANISIGALFIAGLIPALCLLVLLLIAAVIFGKRINVDDAYPV
RMPTRQLLIGAAVGLVMILMIGKGVVAGIATSTEISAFAVVYAIVVGRLAFGELTLKATVKLFVDTAALSGMLLFIVACA
TSLSFALTIEMIPQQCAQLLVAIGADYGPWLFLLLSIVILIIFGAVLEGAPALIIFAPILVPIATQLGFNPLHYAIVMIL
AMGFGLFSPPIGLGLYTTCAICGVPMQDVIKPMAKYLLIILLGIIVIALFPALTTWLPTRLGY
>Mature_622_residues
TLPVTLEMSVKKVAILTQLSRGLTRFTAWGGALALLINVVVVFASVIWRYALHSPIEWAEEVARALMVTLVFFGVATSTG
RGRHIGVDLFLRWLPAVARPYVVHASRWVLVLVALGLTVSSFSLVGISLPQTTEHGLPQAIFVVPVFIGAAVMLVSALDH
ACQAPLKVVLISAAAVALLGGAGYLSLHAPLGFSSLPAALMLACFILGIISGVPIAFTLGMSAMVFFLSDPSLPFVFFAQ
QVTAGVDHFVLLAIPFFLLAGAVMEVNGMSSRLVELIVRGMGRYRGGLNMTTIVSMAFFSGISGSKLADVATVGGVLMPA
VRRARQPAAESAGVFAASAIMAETIPPCVNLIVMGFIANISIGALFIAGLIPALCLLVLLLIAAVIFGKRINVDDAYPVR
MPTRQLLIGAAVGLVMILMIGKGVVAGIATSTEISAFAVVYAIVVGRLAFGELTLKATVKLFVDTAALSGMLLFIVACAT
SLSFALTIEMIPQQCAQLLVAIGADYGPWLFLLLSIVILIIFGAVLEGAPALIIFAPILVPIATQLGFNPLHYAIVMILA
MGFGLFSPPIGLGLYTTCAICGVPMQDVIKPMAKYLLIILLGIIVIALFPALTTWLPTRLGY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=392, Percent_Identity=30.1020408163265, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65543; Mature: 65412

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPVTLEMSVKKVAILTQLSRGLTRFTAWGGALALLINVVVVFASVIWRYALHSPIEWA
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EEVARALMVTLVFFGVATSTGRGRHIGVDLFLRWLPAVARPYVVHASRWVLVLVALGLTV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHH
SSFSLVGISLPQTTEHGLPQAIFVVPVFIGAAVMLVSALDHACQAPLKVVLISAAAVALL
HHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GGAGYLSLHAPLGFSSLPAALMLACFILGIISGVPIAFTLGMSAMVFFLSDPSLPFVFFA
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
QQVTAGVDHFVLLAIPFFLLAGAVMEVNGMSSRLVELIVRGMGRYRGGLNMTTIVSMAFF
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SGISGSKLADVATVGGVLMPAVRRARQPAAESAGVFAASAIMAETIPPCVNLIVMGFIAN
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHH
ISIGALFIAGLIPALCLLVLLLIAAVIFGKRINVDDAYPVRMPTRQLLIGAAVGLVMILM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IGKGVVAGIATSTEISAFAVVYAIVVGRLAFGELTLKATVKLFVDTAALSGMLLFIVACA
HHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLSFALTIEMIPQQCAQLLVAIGADYGPWLFLLLSIVILIIFGAVLEGAPALIIFAPIL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VPIATQLGFNPLHYAIVMILAMGFGLFSPPIGLGLYTTCAICGVPMQDVIKPMAKYLLII
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LLGIIVIALFPALTTWLPTRLGY
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLPVTLEMSVKKVAILTQLSRGLTRFTAWGGALALLINVVVVFASVIWRYALHSPIEWA
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EEVARALMVTLVFFGVATSTGRGRHIGVDLFLRWLPAVARPYVVHASRWVLVLVALGLTV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHH
SSFSLVGISLPQTTEHGLPQAIFVVPVFIGAAVMLVSALDHACQAPLKVVLISAAAVALL
HHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GGAGYLSLHAPLGFSSLPAALMLACFILGIISGVPIAFTLGMSAMVFFLSDPSLPFVFFA
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
QQVTAGVDHFVLLAIPFFLLAGAVMEVNGMSSRLVELIVRGMGRYRGGLNMTTIVSMAFF
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SGISGSKLADVATVGGVLMPAVRRARQPAAESAGVFAASAIMAETIPPCVNLIVMGFIAN
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHH
ISIGALFIAGLIPALCLLVLLLIAAVIFGKRINVDDAYPVRMPTRQLLIGAAVGLVMILM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IGKGVVAGIATSTEISAFAVVYAIVVGRLAFGELTLKATVKLFVDTAALSGMLLFIVACA
HHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLSFALTIEMIPQQCAQLLVAIGADYGPWLFLLLSIVILIIFGAVLEGAPALIIFAPIL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VPIATQLGFNPLHYAIVMILAMGFGLFSPPIGLGLYTTCAICGVPMQDVIKPMAKYLLII
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LLGIIVIALFPALTTWLPTRLGY
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]