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The map label for this gene is mtlR [H]

Identifier: 157368323

GI number: 157368323

Start: 78334

End: 78885

Strand: Direct

Name: mtlR [H]

Synonym: Spro_0074

Alternate gene names: 157368323

Gene position: 78334-78885 (Clockwise)

Preceding gene: 157368322

Following gene: 157368325

Centisome position: 1.44

GC content: 58.15

Gene sequence:

>552_bases
ATGGAAGAAGCACAGGCATTTGAAAATAAGGTTCTGGAACGGCTGAACGCAGGCAAGACGGTGCGCAGTTTCCTGATCGC
GGCGGTAGAGCTGCTGGCGGAGGCGCTGAACGTGCTGGTGGTGCAGGTGTTCCGCAAAGATGACTATGCGGTGAAGTATG
CCGTCGAACCGCTATTGTCCGGCGCCGGTCCATTGGGTGAGCTGTCGGTACGCCTGAAGCTGATGTATGGGCTGGGGGTG
ATTTCACGTCACGAATACGAAGATGCCGAACTGCTGATGGCGATGCGTGAAGAACTGAACCACGACGGGGCGGAATACCG
TTTTGTCGATGATGAAATCCTCGGGCCGTTCGGCGAACTGCATTGCGTAGCTGCGCTGCCGCCGGTACCGACCTTCCTGC
AGCCCGGCGAAGCGGAAGAATCGCTGATCGCCATGCAGCGTCAGCGATACCAGCAGGTGTTACGTTCCACAATGGTACTG
TCGGTCACCGATCTGATCGCCGGTATCGGTGCCAAACAACCGTCCCGGCTTTCCCCGCTCGGCCGCAATTAA

Upstream 100 bases:

>100_bases
AAGTAGATTCAATATGATGAATCTTCGGGCGCAGCAAGTTGCGCCCCTACACCCCGACTTCGGCATTGACGGCGCCACCC
AGGCCATTCGAAAAGCGACG

Downstream 100 bases:

>100_bases
GCAAAGGCCGCACGCCACTCGTCAAATAACAGCCACAGTGCCGTGGCTGCCATCAACCCCGCCATGACGCCGTTAAACAA
TCGCAGTTTCCAGGTTACGC

Product: mannitol repressor protein

Products: NA

Alternate protein names: Mannitol repressor protein [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MEEAQAFENKVLERLNAGKTVRSFLIAAVELLAEALNVLVVQVFRKDDYAVKYAVEPLLSGAGPLGELSVRLKLMYGLGV
ISRHEYEDAELLMAMREELNHDGAEYRFVDDEILGPFGELHCVAALPPVPTFLQPGEAEESLIAMQRQRYQQVLRSTMVL
SVTDLIAGIGAKQPSRLSPLGRN

Sequences:

>Translated_183_residues
MEEAQAFENKVLERLNAGKTVRSFLIAAVELLAEALNVLVVQVFRKDDYAVKYAVEPLLSGAGPLGELSVRLKLMYGLGV
ISRHEYEDAELLMAMREELNHDGAEYRFVDDEILGPFGELHCVAALPPVPTFLQPGEAEESLIAMQRQRYQQVLRSTMVL
SVTDLIAGIGAKQPSRLSPLGRN
>Mature_183_residues
MEEAQAFENKVLERLNAGKTVRSFLIAAVELLAEALNVLVVQVFRKDDYAVKYAVEPLLSGAGPLGELSVRLKLMYGLGV
ISRHEYEDAELLMAMREELNHDGAEYRFVDDEILGPFGELHCVAALPPVPTFLQPGEAEESLIAMQRQRYQQVLRSTMVL
SVTDLIAGIGAKQPSRLSPLGRN

Specific function: Acts as a repressor of the mtlAD operon [H]

COG id: COG3722

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yggD [H]

Homologues:

Organism=Escherichia coli, GI1790029, Length=173, Percent_Identity=78.6127167630058, Blast_Score=273, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007761 [H]

Pfam domain/function: PF05068 MtlR [H]

EC number: NA

Molecular weight: Translated: 20254; Mature: 20254

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAQAFENKVLERLNAGKTVRSFLIAAVELLAEALNVLVVQVFRKDDYAVKYAVEPLLS
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GAGPLGELSVRLKLMYGLGVISRHEYEDAELLMAMREELNHDGAEYRFVDDEILGPFGEL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCHHH
HCVAALPPVPTFLQPGEAEESLIAMQRQRYQQVLRSTMVLSVTDLIAGIGAKQPSRLSPL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRN
CCC
>Mature Secondary Structure
MEEAQAFENKVLERLNAGKTVRSFLIAAVELLAEALNVLVVQVFRKDDYAVKYAVEPLLS
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GAGPLGELSVRLKLMYGLGVISRHEYEDAELLMAMREELNHDGAEYRFVDDEILGPFGEL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCHHH
HCVAALPPVPTFLQPGEAEESLIAMQRQRYQQVLRSTMVLSVTDLIAGIGAKQPSRLSPL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]