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The map label for this gene is ygcU [H]

Identifier: 157162222

GI number: 157162222

Start: 2915196

End: 2916650

Strand: Reverse

Name: ygcU [H]

Synonym: EcHS_A2912

Alternate gene names: 157162222

Gene position: 2916650-2915196 (Counterclockwise)

Preceding gene: 157162223

Following gene: 157162221

Centisome position: 62.81

GC content: 51.07

Gene sequence:

>1455_bases
ATGTCTTTATCTCGCGCAGCGATTGTCGACCAACTAAAGGAAATTGTTGGTGCAGATCGCGTAATTACCGATGAAACAGT
ATTAAAGAAGAACAGTATTGACCGTTTTCGTAAATTTCCGGATATTCATGGCATTTATACTTTGCCGATTCCGGCAGCGG
TCGTAAAACTCGGTTCCACAGAGCAAGTATCCCGTGTGCTGAATTTTATGAATGCGCACAAAATTAACGGTGTGCCGCGT
ACCGGCGCTTCCGCCACTGAAGGTGGGCTGGAAACCGTTGTGGAAAACTCGGTGGTGCTCGACGGCTCCGCCATGAATCA
AATCATTAATATTGATATTGAGAATATGCAGGCGACGGCGCAATGTGGCGTTCCGCTGGAGGTGCTGGAAAATGCGTTGC
GTGAAAAAGGTTACACCACGGGGCATTCTCCGCAGTCAAAGCCGCTGGCTCAGATGGGCGGCCTGGTAGCAACCCGCAGT
ATCGGGCAGTTCTCCACACTCTACGGCGCAATCGAAGATATGGTCGTTGGTCTGGAAGCAGTATTGGCTGATGGCACCGT
CACACGCATTAAAAACGTGCCACGCCGCGCGGCTGGCCCGGACATTCGCCACATCATCATCGGTAACGAAGGTGCACTTT
GCTATATCACTGAAGTAACAGTGAAAATCTTTAAATTCACCCCGGAAAACAACCTCTTCTACGGCTATATCCTGGAAGAC
ATGAAAACCGGCTTCAACGTCCTGCGTGAAGTCATGGTGGAAGGGTATCGTCCGTCGATCGCTCGTTTGTATGACGCTGA
AGATGGCACCCAACACTTCACCCATTTTGCAGACGGAAAATGCGTGCTGATCTTTATGGCTGAAGGTAACCCTCGCATTG
CGAAGGCGACGGGCGAAGGGATTGCGGAAATCGTTGCCCGCTACCCGCAATGCCAGCGCGTGGACAGCAAGCTGATCGAA
ACCTGGTTTAACAACCTGAACTGGGGACCGGATAAAGTGGCTGCCGAACGTGTGCAGATCCTCAAAACCGGCAACATGGG
CTTTACCACTGAAGTGTCCGGCTGCTGGAGCTGCATCCACGAAATCTACGAAAGCGTTATTAACCGTATTCGTACTGAGT
TCCCGCACGCCGACGACATCACCATGCTGGGCGGTCACTCCTCTCATAGCTATCAGAACGGCACCAACATGTACTTCGTC
TACGACTACAACGTCGTTGACTGTAAGCCGGAAGAGGAAATCGACAAGTACCACAATCCGCTCAACAAAATCATCTGTGA
AGAAACCATTCGCCTCGGCGGTTCGATGGTGCACCACCACGGCATTGGTAAACATCGCGTTCACTGGAGCAAGCTGGAAC
ACGGCAGCGCGTGGGCGTTGCTGGAAGGGCTGAAAAAGCAGTTTGATCCTAACGGCATTATGAATACGGGTACTATCTAT
CCGATTGAAAAATAA

Upstream 100 bases:

>100_bases
AGTGGTCGATGGTGGTTATTTAGTGCGCTAATCCATAACGGTGGTTTCTGTTTTCTCTTATTAATGATTATTCCATTTTT
ATTATCAGGAAGGAATTACT

Downstream 100 bases:

>100_bases
TGTATCAGGCAGCGTTCCGCGATGACGGGGCGTTGCCTTTTCGGCTTCTCAGGCGAGAAGCCGTTCTTATTACCGGACAA
TGAAGGGGTAAAGATGAACA

Product: FAD binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPR
TGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
MKTGFNVLREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIE
TWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFV
YDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
PIEK

Sequences:

>Translated_484_residues
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPR
TGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
MKTGFNVLREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIE
TWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFV
YDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
PIEK
>Mature_483_residues
SLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRT
GASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSI
GQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDM
KTGFNVLREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIET
WFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVY
DYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYP
IEK

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI4501993, Length=456, Percent_Identity=28.5087719298246, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI37595756, Length=494, Percent_Identity=21.6599190283401, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI119964728, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI48994907, Length=484, Percent_Identity=99.3801652892562, Blast_Score=1005, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556096, Length=462, Percent_Identity=27.9220779220779, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI71992373, Length=492, Percent_Identity=24.5934959349593, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71992381, Length=489, Percent_Identity=23.9263803680982, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320027, Length=175, Percent_Identity=32, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320023, Length=169, Percent_Identity=30.1775147928994, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320764, Length=179, Percent_Identity=27.3743016759777, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24653753, Length=486, Percent_Identity=26.1316872427983, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI18921117, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639277, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639275, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 53682; Mature: 53551

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGST
CCCHHHHHHHHHHHHHCCCCEECCHHHHHHCCHHHHHCCCCCCCEEECCHHHHHHHCCCH
EQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEECCHHHHHEEEEEECCCCHHH
QCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEA
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
VLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
HHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCEEEEEEHHH
MKTGFNVLREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEG
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHEECCCCEEEEEEECCCCCEEECCCHH
IAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIH
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
EIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNP
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCH
LNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
HHHHHHHHHHHHCCHHHHHCCCCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
PIEK
ECCC
>Mature Secondary Structure 
SLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGST
CCHHHHHHHHHHHHHCCCCEECCHHHHHHCCHHHHHCCCCCCCEEECCHHHHHHHCCCH
EQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEECCHHHHHEEEEEECCCCHHH
QCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEA
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
VLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
HHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCEEEEEEHHH
MKTGFNVLREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEG
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHEECCCCEEEEEEECCCCCEEECCCHH
IAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIH
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
EIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNP
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCH
LNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
HHHHHHHHHHHHCCHHHHHCCCCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
PIEK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]