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The map label for this gene is eprH [H]

Identifier: 157155332

GI number: 157155332

Start: 3194586

End: 3195767

Strand: Reverse

Name: eprH [H]

Synonym: EcE24377A_3179

Alternate gene names: 157155332

Gene position: 3195767-3194586 (Counterclockwise)

Preceding gene: 157159225

Following gene: 157157566

Centisome position: 64.18

GC content: 32.49

Gene sequence:

>1182_bases
ATGGAAAATAATGATAAATTCTTATCACAAGAATTATTGGAATCTTATGCCATTCGTTTGTTGAGCGGGCCATTGAATGG
ATGCGAGTATGAAATACTTAATGGGCGTCTACTTGTTATCATTGGTAATGATGTTTCGTTAGGAAGAAGTGATGCTTTTT
CTGAGTTACCAGAAAACACAATAGTCGTTCCTTATGGCGAGCTTACAGGTAGTTTTGAGATAATAATTACTACCGACCAT
GATCTGGTAGTAACATTCAGAGAATTAACAGCACAAGAACCTGAAGATAGAACGTTAACATTGAATCAGCAAATAGAAGT
TTTAGGTCTCAAATTTGCTGTAAAAGAAAAAAATGAAGTTTGGCAGTATTCATTGCCAGGCATTATTGAAAATAACATTA
TTTCTACAAAACAACATTTCTTTAGCAGTAAGCTGTTTAAGTATGTAATGCTTTTTTTTCTTTTTGCTATCATTTTCATT
GCTTTTTATATTGTTAATGCCAGTAATGATCCGCAGCTGAGACATATCGATAAAATTCTTGTAAACAAAAACAGGAATTA
TGAAATTTTATATGGTAGAGATCATGTTATCTATATTAATACCAATATTTTGGATGAAGCAGTCTGGGTCAAACAAGCAC
TGGAAAAAAATCAACCAGGAAAGCCAGTACGGGTGATAAATCCTGATGATGAATCGATACGAATTTTTTCATGGCTTGCT
GATAATTTCCCTGATTTACAATATTTTAAACTTCAACTATTAGATGCCAGTAATCTAAGATTGACAGTGAGTAAGCAACG
GAACGCTATCACACAGCAACTAATCGATAATCTTATTAAAGGATTACTGCAAACTATGCCATATGCCAGCAATATAAGTA
TTGCGGTATTAGATGATAATGTATTGGAAAGTCAGGCTATTGAAACGTTGTCAGCGATAGGTCTTTCTTATGAAAAATAT
AAAACAGCTAACAATGTGTATTTCAATATCATTGGTACGTTAAGTGACAGTGAATTAAATAAAATTAATAACTATGTTGA
CGAATATTATAAACAATGGGGTAAACAATATGTAAGATTTAATGTGAATTTGAAAAATCAGGACACAAATAATAGTTCAT
TTAGCTACGGAGATAACCGATTCGAGAAGTCTCAAGGTAGCAACTGGACATTTCAGGAATAA

Upstream 100 bases:

>100_bases
TTATAATTTTTTTATTCTGTGTCATCATAATTTGGTCATGATATTTCCGTCTTGTTACACTACTCTAAACTAGAGCTTAT
GGAATTAGCGGGTGGTATTC

Downstream 100 bases:

>100_bases
TTGAGGAGGACTTATGGCAGATTGGAATGGTTATATTATGGATATCAGCAATCAATTTGATCAGGGCGTTGATGATCTGA
CCAGCAAGTTGAAAAAGCGT

Product: type III secretion apparatus protein EprH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIITTDH
DLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFI
AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
DNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSYEKY
KTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE

Sequences:

>Translated_393_residues
MENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIITTDH
DLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFI
AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
DNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSYEKY
KTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
>Mature_393_residues
MENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIITTDH
DLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFI
AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
DNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSYEKY
KTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 45287; Mature: 45287

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCHHHHHCCCCC
IVVPYGELTGSFEIIITTDHDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEV
EEEEECCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCEEEECCCEEEEEEEEEEECCCCE
WQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFIAFYIVNASNDPQLRHIDKIL
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
VNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
HCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEHH
DNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDN
CCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
VLESQAIETLSAIGLSYEKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRF
HHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEE
NVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCHHHHHCCCCC
IVVPYGELTGSFEIIITTDHDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEV
EEEEECCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCEEEECCCEEEEEEEEEEECCCCE
WQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFIAFYIVNASNDPQLRHIDKIL
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
VNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFSWLA
HCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEHH
DNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDN
CCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
VLESQAIETLSAIGLSYEKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRF
HHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEE
NVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]