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The map label for this gene is eprK [H]

Identifier: 157157566

GI number: 157157566

Start: 3193251

End: 3193985

Strand: Reverse

Name: eprK [H]

Synonym: EcE24377A_3177

Alternate gene names: 157157566

Gene position: 3193985-3193251 (Counterclockwise)

Preceding gene: 157155332

Following gene: 157158255

Centisome position: 64.14

GC content: 36.19

Gene sequence:

>735_bases
ATGAAATATATATCATTATTATTGTTTATCCTGCTGTTGTGCGGCTGCAAGCAGCAGGAATTATTGAACCATCTTGATCA
ACAGCAAGCTAATGATGTCCTTGCTGTTTTACAAAGACATAATATTAATGCTGAAAAGAAGGATCAAGGCAAAACAGGAT
TTTCAATATTTGTCGAACCAACGGATTTTGCTTCTGCGGTGGATTGGCTAAAAATCTACAATCTACCGGGTAAGCCTGAT
ATTCAAATATCGCAGATGTTCCCTGCAGATGCACTCGTTTCATCTCCACGAGCGGAAAAAGCAAGGCTATATTCTGCTAT
TGAGCAGCGGTTAGAGCAATCTCTCAAAATTATGGATGGCATTATTTCTTCGAGAGTACATGTTAGTTACGATGTTGATA
ATGGCGATAGTGGTAAAACTGCTTTACCAATTCATATTTCTGTACTTGCAGTATATGAAAAAGATATCAACCCAGAAATA
AAAATAAATGATATCAAGAGATTTATTGTTAATAGCTCTGCAAGCGTACAATATGAAAATATTTCTGTTGTATTGTCAAA
ACGAAGAGACATTATTGAGCAAGCACCAACATATGAAATTAGCGAACCTGTTTTTGCTTATGATAAGGCTATGCCGGTTT
CTATCTTACTTGCATTAATATCCGTAGCGACTTGCTGGCTGTTATGGAAGTATAGGGCCATTCTAACTAATTTAGTCAGG
TTGAAAATTAAGTAG

Upstream 100 bases:

>100_bases
TTAGTCTTGCAGGATCATGTGCTTAATTATAATGTCGAGGTTTCATTGGTGGAACATTAGCAAGAAAAATTGTCGCTGCA
GTTGAGACGTTGACCCGCTC

Downstream 100 bases:

>100_bases
ACATATGAGAGCGTTATGAATCTTGCCCTAAGAAAGATTATATATGATCCAATTAGTTATATTCATCCTCAACGAGTAAG
CTTGAATAATACACCTATTA

Product: type III secretion apparatus lipoprotein EprK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIFVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIISSRVHVSYDVDNGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSSASVQYENISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
LKIK

Sequences:

>Translated_244_residues
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIFVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIISSRVHVSYDVDNGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSSASVQYENISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
LKIK
>Mature_244_residues
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIFVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIISSRVHVSYDVDNGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSSASVQYENISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
LKIK

Specific function: Required for invasion of epithelial cells. Could be involved in protein secretion [H]

COG id: COG4669

COG function: function code U; Type III secretory pathway, lipoprotein EscJ

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yscJ lipoprotein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003282
- InterPro:   IPR006182 [H]

Pfam domain/function: PF01514 YscJ_FliF [H]

EC number: NA

Molecular weight: Translated: 27575; Mature: 27575

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIFVEP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
TDFASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDG
CHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IISSRVHVSYDVDNGDSGKTALPIHISVLAVYEKDINPEIKINDIKRFIVNSSASVQYEN
HHHCCEEEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEHH
ISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKIK
HCCC
>Mature Secondary Structure
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIFVEP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
TDFASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDG
CHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IISSRVHVSYDVDNGDSGKTALPIHISVLAVYEKDINPEIKINDIKRFIVNSSASVQYEN
HHHCCEEEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEHH
ISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
HHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKIK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]