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The map label for this gene is ycgO [H]

Identifier: 156978292

GI number: 156978292

Start: 2172022

End: 2173578

Strand: Direct

Name: ycgO [H]

Synonym: VIBHAR_07099

Alternate gene names: 156978292

Gene position: 2172022-2173578 (Clockwise)

Preceding gene: 156978291

Following gene: 156978294

Centisome position: 98.55

GC content: 48.3

Gene sequence:

>1557_bases
TTGCTGCGATGGCAAAATATCAAAGAGGGCAAGGAAGGAAATAATTATAACGAGGACTATCAAATGATAGAAAATAGCTT
TGCTATCACGACCACTTTCGTGGCGTACTTACTAATTATGGTTGCCATTGGCGTTTACGCGTATAAGAGGACTTCCAATT
CATCTGACTACTTCCTAGGTGGTCGTAGCCTTGGTCCATGGCCAGCGGCACTCTCTGCGGGCGCATCAGACATGAGTGGC
TGGTTGCTACTTGGTCTTCCGGGGTATGCGTATGCAGCAGGTATTGAAGCGTTTTGGCTAGCAGCTGGTCTGCTTGTGGG
TACATGGCTAAACTGGTTAATCAGTGCAAAACGCCTACGTACGTACAGCATTCAAACGGATGCACTAACGCTGCCTGAAT
TCCTGTCGCGTCGCTTTAACGATAAGTCGAAACTGATTCAGACAATCTCTGCGTTCTTCATTCTTCTATTCTTCCTTTTC
TACACCAGCTCAGGCTTGGTAGCAGGTGGTAAACTGTTTGAGACCGTATTCGGCTTGGATTACAGCATTGCCGTTATCGT
TGGTACGGTGTGTGTGGTTTCATACACGCTATTTGGTGGTTTCCTAGCGGTATCTTGGACGGACTTGGTACAAGGTCTAT
TGATGGCGGCGGCGCTGATGATCGTGCCTGTTGCCGTTATGGATGGTGGCCTAGGTCAACTAGCGACGGATATGCACAAC
ATCAACCCAGAGCTATTAACGCTATGGAACGACGTAAAAGGTGAGCCTCTATCGGCTGTCGCGATCAGCTCTTTGGTGGC
ATGGGGTCTTGGTTACTTTGGTCAACCGCACATCCTAGCGCGTTTTAAAGCTTCTCGTTCAAATAAAGATCTAACAACAG
CGCGTCGTATCGCTGTGGGTTGGACTGCGCTTTCTATGGCGGGTGCAATGCTAGTTGGTCTTGTTGGTCTAGTGTGGGTA
ACTGGTCACCCTGGTATGCAGGTTGATGATGGCGAGAAAATCTTCATGCTATTGGTGAACACGGTATTCCACCCAGTGAT
TGCAGGTATCCTATTGGCGGCAATCCTAGCGGCGGTAATGAGTACAGCAGATTCACAGCTTCTAGTATCTTCATCAGCTC
TTGCAGAAGACTTCTACAAGCAAGTGATTAAGCCAGATGCAACGTCTGAAGAAGTGGTCATGATTGGTCGTGTAGGCGTT
ATCGTGATTTCTCTTATCGCGCTATTCCTAGCAATGACGCCAGACAGCTCTGTTCTTGGTCTTGTATCTTACGCTTGGGC
AGGCTTTGGTGCTGCGTTTGGTCCAGCAGTTGTGCTTAGCCTTTACTGGAGCTGCATGAACCGTAACGGCGCACTAGCAG
GTATCCTAATCGGTGGCGTGACTATCGTTGTTTGGAAACAGCTAACAGGCGGTTGGTTCGATGTGTACGAAATCGTACCG
GGCATCATCTTCTCTACTATCGCTATCGTGGTGGTGAGCAAAATGACTGGCGGTGCAGCGCAAGAAGTACTTGAGCAACA
CAAAGAATACGAGAAGAAATTGGTTGAGCTAGACTAA

Upstream 100 bases:

>100_bases
TCGAGTTGGGAAGCGACTCCCACTAACCTGACTTGTGATACCAATCTGAATCAAAAGGGCCTGAGAGCTTACTCGGGTTG
GTATCTCTTGCTTTGATGTA

Downstream 100 bases:

>100_bases
TCATTCTCAAATAAAAACAAAGCCCGCGTTCATCGCGGGCTTTTTTGCTTTTAGTGACGGATTTTGGCGTAAACTACCGT
GTTACTCAGTTCTCCTGAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLRWQNIKEGKEGNNYNEDYQMIENSFAITTTFVAYLLIMVAIGVYAYKRTSNSSDYFLGGRSLGPWPAALSAGASDMSG
WLLLGLPGYAYAAGIEAFWLAAGLLVGTWLNWLISAKRLRTYSIQTDALTLPEFLSRRFNDKSKLIQTISAFFILLFFLF
YTSSGLVAGGKLFETVFGLDYSIAVIVGTVCVVSYTLFGGFLAVSWTDLVQGLLMAAALMIVPVAVMDGGLGQLATDMHN
INPELLTLWNDVKGEPLSAVAISSLVAWGLGYFGQPHILARFKASRSNKDLTTARRIAVGWTALSMAGAMLVGLVGLVWV
TGHPGMQVDDGEKIFMLLVNTVFHPVIAGILLAAILAAVMSTADSQLLVSSSALAEDFYKQVIKPDATSEEVVMIGRVGV
IVISLIALFLAMTPDSSVLGLVSYAWAGFGAAFGPAVVLSLYWSCMNRNGALAGILIGGVTIVVWKQLTGGWFDVYEIVP
GIIFSTIAIVVVSKMTGGAAQEVLEQHKEYEKKLVELD

Sequences:

>Translated_518_residues
MLRWQNIKEGKEGNNYNEDYQMIENSFAITTTFVAYLLIMVAIGVYAYKRTSNSSDYFLGGRSLGPWPAALSAGASDMSG
WLLLGLPGYAYAAGIEAFWLAAGLLVGTWLNWLISAKRLRTYSIQTDALTLPEFLSRRFNDKSKLIQTISAFFILLFFLF
YTSSGLVAGGKLFETVFGLDYSIAVIVGTVCVVSYTLFGGFLAVSWTDLVQGLLMAAALMIVPVAVMDGGLGQLATDMHN
INPELLTLWNDVKGEPLSAVAISSLVAWGLGYFGQPHILARFKASRSNKDLTTARRIAVGWTALSMAGAMLVGLVGLVWV
TGHPGMQVDDGEKIFMLLVNTVFHPVIAGILLAAILAAVMSTADSQLLVSSSALAEDFYKQVIKPDATSEEVVMIGRVGV
IVISLIALFLAMTPDSSVLGLVSYAWAGFGAAFGPAVVLSLYWSCMNRNGALAGILIGGVTIVVWKQLTGGWFDVYEIVP
GIIFSTIAIVVVSKMTGGAAQEVLEQHKEYEKKLVELD
>Mature_518_residues
MLRWQNIKEGKEGNNYNEDYQMIENSFAITTTFVAYLLIMVAIGVYAYKRTSNSSDYFLGGRSLGPWPAALSAGASDMSG
WLLLGLPGYAYAAGIEAFWLAAGLLVGTWLNWLISAKRLRTYSIQTDALTLPEFLSRRFNDKSKLIQTISAFFILLFFLF
YTSSGLVAGGKLFETVFGLDYSIAVIVGTVCVVSYTLFGGFLAVSWTDLVQGLLMAAALMIVPVAVMDGGLGQLATDMHN
INPELLTLWNDVKGEPLSAVAISSLVAWGLGYFGQPHILARFKASRSNKDLTTARRIAVGWTALSMAGAMLVGLVGLVWV
TGHPGMQVDDGEKIFMLLVNTVFHPVIAGILLAAILAAVMSTADSQLLVSSSALAEDFYKQVIKPDATSEEVVMIGRVGV
IVISLIALFLAMTPDSSVLGLVSYAWAGFGAAFGPAVVLSLYWSCMNRNGALAGILIGGVTIVVWKQLTGGWFDVYEIVP
GIIFSTIAIVVVSKMTGGAAQEVLEQHKEYEKKLVELD

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=493, Percent_Identity=45.4361054766734, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI14140236, Length=479, Percent_Identity=21.7118997912317, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4507035, Length=383, Percent_Identity=25.3263707571802, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI256985183, Length=446, Percent_Identity=24.8878923766816, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI109659836, Length=480, Percent_Identity=23.75, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI167466278, Length=462, Percent_Identity=26.6233766233766, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4507031, Length=486, Percent_Identity=23.4567901234568, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI109659839, Length=496, Percent_Identity=23.5887096774194, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI4507033, Length=439, Percent_Identity=22.5512528473804, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI11141885, Length=459, Percent_Identity=25.7080610021786, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI1787251, Length=491, Percent_Identity=50.10183299389, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI87082237, Length=456, Percent_Identity=30.9210526315789, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1790503, Length=458, Percent_Identity=25.764192139738, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790113, Length=422, Percent_Identity=24.8815165876777, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221459584, Length=385, Percent_Identity=25.4545454545455, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24651741, Length=201, Percent_Identity=31.8407960199005, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221459588, Length=386, Percent_Identity=25.6476683937824, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221459586, Length=380, Percent_Identity=25.7894736842105, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24645928, Length=394, Percent_Identity=24.3654822335025, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24648033, Length=406, Percent_Identity=23.3990147783251, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356865, Length=406, Percent_Identity=23.3990147783251, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24651739, Length=217, Percent_Identity=26.2672811059908, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55794; Mature: 55794

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWQNIKEGKEGNNYNEDYQMIENSFAITTTFVAYLLIMVAIGVYAYKRTSNSSDYFLG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GRSLGPWPAALSAGASDMSGWLLLGLPGYAYAAGIEAFWLAAGLLVGTWLNWLISAKRLR
CCCCCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYSIQTDALTLPEFLSRRFNDKSKLIQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLD
EEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
YSIAVIVGTVCVVSYTLFGGFLAVSWTDLVQGLLMAAALMIVPVAVMDGGLGQLATDMHN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
INPELLTLWNDVKGEPLSAVAISSLVAWGLGYFGQPHILARFKASRSNKDLTTARRIAVG
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
WTALSMAGAMLVGLVGLVWVTGHPGMQVDDGEKIFMLLVNTVFHPVIAGILLAAILAAVM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STADSQLLVSSSALAEDFYKQVIKPDATSEEVVMIGRVGVIVISLIALFLAMTPDSSVLG
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHH
LVSYAWAGFGAAFGPAVVLSLYWSCMNRNGALAGILIGGVTIVVWKQLTGGWFDVYEIVP
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
GIIFSTIAIVVVSKMTGGAAQEVLEQHKEYEKKLVELD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRWQNIKEGKEGNNYNEDYQMIENSFAITTTFVAYLLIMVAIGVYAYKRTSNSSDYFLG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GRSLGPWPAALSAGASDMSGWLLLGLPGYAYAAGIEAFWLAAGLLVGTWLNWLISAKRLR
CCCCCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYSIQTDALTLPEFLSRRFNDKSKLIQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLD
EEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
YSIAVIVGTVCVVSYTLFGGFLAVSWTDLVQGLLMAAALMIVPVAVMDGGLGQLATDMHN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
INPELLTLWNDVKGEPLSAVAISSLVAWGLGYFGQPHILARFKASRSNKDLTTARRIAVG
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
WTALSMAGAMLVGLVGLVWVTGHPGMQVDDGEKIFMLLVNTVFHPVIAGILLAAILAAVM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STADSQLLVSSSALAEDFYKQVIKPDATSEEVVMIGRVGVIVISLIALFLAMTPDSSVLG
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHH
LVSYAWAGFGAAFGPAVVLSLYWSCMNRNGALAGILIGGVTIVVWKQLTGGWFDVYEIVP
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
GIIFSTIAIVVVSKMTGGAAQEVLEQHKEYEKKLVELD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]