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The map label for this gene is mrdB [H]

Identifier: 156978229

GI number: 156978229

Start: 2110124

End: 2111206

Strand: Direct

Name: mrdB [H]

Synonym: VIBHAR_07034

Alternate gene names: 156978229

Gene position: 2110124-2111206 (Clockwise)

Preceding gene: 156978228

Following gene: 156978234

Centisome position: 95.74

GC content: 48.57

Gene sequence:

>1083_bases
ATGAACAAGCGTTTCTTCCCTAGGATTGATTTGCCACTGCTGATGGCGATCATTCCGATCATGCTATTGAGTTCACTCAC
TCTCTGGAGTGCCAGTGGATTCAATGAAGCTATGCTCTTTAAGCACCTCGCTCGATGCGGTTTGACGCTGGTGTGTATTT
TGGTCATGTCGTCGATTCCTGCGTCCAGTTATCAACGTTCAGCGCCTTATTTGTATCTGGTTGCGGTTTCGCTCTTGGCG
GCCGTTGCCCTGTTTGGTGATAGCACCAATGGCTCACAGCGCTGGCTTGATATTGGCTTCTTCCGCTTTCAACCCTCAGA
GCTGATCAAGCTCTCCATTCCCATTATGATCGCGTGGATGCTGCATCTAGAAGGTGGGCGACCAGACATTCGCAAAATTG
CTTTCTGTTTGCTGATCACCTTTGTGCCTGCGGGCTTGATTGCCTTACAACCAGACTTGGACGGCGCTATCTTCACCGTG
ATTTACGCGTTGTTTGTGCTGTTCTTTGCAGGCATGAGCTGGAAGATAATTGGCGGCTTTTTAGTGAGCATTCTAACGCT
GGCACCAATACTTTGGTTCTTTGTGATGGAAGCGTATCAAAAGAGCCGTGTAACGCAGTTCTTGCATCCTGAATCGGATC
CACTGGGTTCTGGCTACCAAATCATCCAATCATTGATTGCGATTGGTTCTGGCGGCATGAAAGGTAAAGGCTGGATGAAT
GCTACTCAAGGTACGTTAGGGTTTATTCCAGAGAGCCATACTGACTTTATCTTTTCGACCTACGCAGAAGAATGGGGCTT
TATTGGTTTTGTGGTGTTGTTAGCGTTGTATTTATTCATTACGGCGCGTGTGATGCTGCTAGCGTGCCAATCCGAGCACT
TCTTCAGTCGCTTAGTGAGCGGCGCATTGGCGATGAGCTTCTTCCTTTACGCCTTCATCAACACAGGCATGGTAAGTGGC
TTGTTGCCAGTAATGGGCAGCCCACTACCGTTCTTTAGCTACGGTGGTACTGCGATGCTAACCCAAGGCATCTGTTTTGG
CGTGATCATGTCTCTGTGTTACTCCAAGTACCGCAACACCTAA

Upstream 100 bases:

>100_bases
TCTGTTATCTCCAAATTGGATTCTTAGCATCGGAATAGTTTGAGCTCGCAGAGTTCTGGTTGTTTTCGCCCCGCGTTGGG
GCGTTTTTAGGTTGTAGAAG

Downstream 100 bases:

>100_bases
ACGCTAGTCACAATAGAAAAGACAAACAACACGATCAAAAAAGGCTTCCCTCGGGAAGCCTTTTTTACAACTGGAGAACC
GAATTACAGTTCGCCGTTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNKRFFPRIDLPLLMAIIPIMLLSSLTLWSASGFNEAMLFKHLARCGLTLVCILVMSSIPASSYQRSAPYLYLVAVSLLA
AVALFGDSTNGSQRWLDIGFFRFQPSELIKLSIPIMIAWMLHLEGGRPDIRKIAFCLLITFVPAGLIALQPDLDGAIFTV
IYALFVLFFAGMSWKIIGGFLVSILTLAPILWFFVMEAYQKSRVTQFLHPESDPLGSGYQIIQSLIAIGSGGMKGKGWMN
ATQGTLGFIPESHTDFIFSTYAEEWGFIGFVVLLALYLFITARVMLLACQSEHFFSRLVSGALAMSFFLYAFINTGMVSG
LLPVMGSPLPFFSYGGTAMLTQGICFGVIMSLCYSKYRNT

Sequences:

>Translated_360_residues
MNKRFFPRIDLPLLMAIIPIMLLSSLTLWSASGFNEAMLFKHLARCGLTLVCILVMSSIPASSYQRSAPYLYLVAVSLLA
AVALFGDSTNGSQRWLDIGFFRFQPSELIKLSIPIMIAWMLHLEGGRPDIRKIAFCLLITFVPAGLIALQPDLDGAIFTV
IYALFVLFFAGMSWKIIGGFLVSILTLAPILWFFVMEAYQKSRVTQFLHPESDPLGSGYQIIQSLIAIGSGGMKGKGWMN
ATQGTLGFIPESHTDFIFSTYAEEWGFIGFVVLLALYLFITARVMLLACQSEHFFSRLVSGALAMSFFLYAFINTGMVSG
LLPVMGSPLPFFSYGGTAMLTQGICFGVIMSLCYSKYRNT
>Mature_360_residues
MNKRFFPRIDLPLLMAIIPIMLLSSLTLWSASGFNEAMLFKHLARCGLTLVCILVMSSIPASSYQRSAPYLYLVAVSLLA
AVALFGDSTNGSQRWLDIGFFRFQPSELIKLSIPIMIAWMLHLEGGRPDIRKIAFCLLITFVPAGLIALQPDLDGAIFTV
IYALFVLFFAGMSWKIIGGFLVSILTLAPILWFFVMEAYQKSRVTQFLHPESDPLGSGYQIIQSLIAIGSGGMKGKGWMN
ATQGTLGFIPESHTDFIFSTYAEEWGFIGFVVLLALYLFITARVMLLACQSEHFFSRLVSGALAMSFFLYAFINTGMVSG
LLPVMGSPLPFFSYGGTAMLTQGICFGVIMSLCYSKYRNT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=46.2462462462462, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1786277, Length=314, Percent_Identity=33.4394904458599, Blast_Score=168, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39791; Mature: 39791

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRFFPRIDLPLLMAIIPIMLLSSLTLWSASGFNEAMLFKHLARCGLTLVCILVMSSIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ASSYQRSAPYLYLVAVSLLAAVALFGDSTNGSQRWLDIGFFRFQPSELIKLSIPIMIAWM
CHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECHHHHHHHHHHHHHHHH
LHLEGGRPDIRKIAFCLLITFVPAGLIALQPDLDGAIFTVIYALFVLFFAGMSWKIIGGF
HHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LVSILTLAPILWFFVMEAYQKSRVTQFLHPESDPLGSGYQIIQSLIAIGSGGMKGKGWMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
ATQGTLGFIPESHTDFIFSTYAEEWGFIGFVVLLALYLFITARVMLLACQSEHFFSRLVS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALAMSFFLYAFINTGMVSGLLPVMGSPLPFFSYGGTAMLTQGICFGVIMSLCYSKYRNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKRFFPRIDLPLLMAIIPIMLLSSLTLWSASGFNEAMLFKHLARCGLTLVCILVMSSIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ASSYQRSAPYLYLVAVSLLAAVALFGDSTNGSQRWLDIGFFRFQPSELIKLSIPIMIAWM
CHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECHHHHHHHHHHHHHHHH
LHLEGGRPDIRKIAFCLLITFVPAGLIALQPDLDGAIFTVIYALFVLFFAGMSWKIIGGF
HHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LVSILTLAPILWFFVMEAYQKSRVTQFLHPESDPLGSGYQIIQSLIAIGSGGMKGKGWMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
ATQGTLGFIPESHTDFIFSTYAEEWGFIGFVVLLALYLFITARVMLLACQSEHFFSRLVS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALAMSFFLYAFINTGMVSGLLPVMGSPLPFFSYGGTAMLTQGICFGVIMSLCYSKYRNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]