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The map label for this gene is speA [H]

Identifier: 156977941

GI number: 156977941

Start: 1868534

End: 1870456

Strand: Direct

Name: speA [H]

Synonym: VIBHAR_06737

Alternate gene names: 156977941

Gene position: 1868534-1870456 (Clockwise)

Preceding gene: 156977939

Following gene: 156977942

Centisome position: 84.78

GC content: 47.79

Gene sequence:

>1923_bases
GTGAGAATCGAGTTGGAAAAAGCAACTAAATTAGACCGCATCCGCGCGGACTACAACGTTCACTACTGGAGCCAAGGCTT
CTACGGAATTGATGACCAAGGCGAGGTATACGTATCTCCTCGTAGTGACCATGCACACCAAATCCCTTTCAGTGCGATTG
TTAATGAGCTAGAAGCCAAGCAGCTGAACCTGCCTGTATTAGTGCGCTTCCCGCAAATCGTGCACCAACGCGTGCATGGC
ATTTGCCAAGCTTTCAACCAAGCGATTGAAGAATACCAATATCCAAATAAATACCTGCTGGTATACCCAATTAAAGTAAA
CCAACAGCGTGAAGTGGTTGATGAGATCTTAGCGAGTCAAGCACAGCTAGAAAATAAACAGCTGGGTCTTGAAGCAGGCA
GTAAGCCAGAGCTATTAGCCGTATTGGCATTGGCTCAACAGGGCAGCTCCGTGATCGTGTGTAATGGCTACAAAGACCGT
GAATACGTGCGCCTTGCACTGATCGGTGAAAAGCTAGGCCACAAAGTATTTATCGTACTAGAGAAGCTATCTGAGCTTGA
TCTGGTACTTGAAGAAGCAAAAAGCTTGGGCGTAACACCACGTCTTGGTTTGCGTATCCGCCTTGCGTCTCAAGGTGCAG
GTAAATGGCAAGCAAGCGGCGGTGAGAAATCGAAGTTCGGTCTATCGGCATCTCAAGTATTGAGCGTGATTGATCGTCTA
AAATGCGAAGACCAGCTGGACACCATGCAATTGGTTCACTTCCACCTTGGCTCACAGATGGCAAACATCCGTGACGTGCG
TAATGGTGTAAACGAATCGGCACGTTTCTACTGTGAATTACGTGCCATGGGTGCAAACATTGATTACTTCGATGTTGGCG
GTGGTTTAGCAGTAGACTACGACGGCACACGTAGCCAATCTTCGAACTCGATGAACTACGGGCTTGCAGAGTACGCGCGC
AACATCGTGAATACGGTAGGTGATGTGTGTCAGCAGTACGAACAACCGATGCCAGTGATCATCTCTGAATCGGGGCGCTC
TCTAGCGGCACACCACGCGGTGCTGATTTCTAACGTTATTGGCACAGAAACGTACCAACCAGAAGAAGTATTCGAGCCAG
CGGTAGATGCTCCGTTCTTGCTACAAAACATGTGGCGAAACTGGGAGAACCTGCAAGATGGTACGGATGCGCGTGCATTA
ATTGAAATTTACAACGATACCCAAAGCGATTTGGCTGAGGTTCACTCACAATTCGCTACTGGCGTACTGAATCTTGAACA
ACGTGCGTGGGCAGAACAACTGTCGCTGCGCATTTACTTCGAGCTAAGTCGTCAAATGAGTACCAAGAACCGTTTCCACC
GTCCTATTTTGGATGAGTTGAGCGAACGTCTTGCGGACAAGTTCTTCGTGAACTTCTCTCTTTTCCAATCCCTGCCAGAT
GCATGGGGTATTGATCAGGTATTCCCTGTTCTGCCTCTTTCTGGTCTTGGTGATGTGGAAGAGCGTCGTGCGGTGATGTT
GGACATCACTTGTGACTCCGATGGTGTGATTGACCATTACGTTGATGGCCAAGGTATCGAGAGCACACTACCAGTACCAG
CATGGAGCAAAGACAAACCGTACCTAATGGGCTTCTTCCTAGTAGGCGCATACCAAGAGATCCTTGGTGACATGCACAAC
CTATTTGGTGATACCCACAGTGCAGTAGTCAATGTTGATGAAGAAGGTCAGTTTGAGATCAGCTACATCAACGAAGGTGA
TAGCGTAGAAGACATGATGCGCTACGTTCATATCGACGTAGATGCGATTCGTGATAATTACAAACAATTGGTTTCAGCAC
GTGTTGAAGCCAGTGAACAAGAACAAATCCTAGCTGAACTAGAACAAGGTTTGGCAGGCTACACCTATTTAGAGGACTTC
TGA

Upstream 100 bases:

>100_bases
CGCGCACACGGAGTTCGTGTCAGGGTATGAGGTTAGCGCCTCATGATTTGCTTTTTTGTATTTTCTCCTCTACTTCCTAT
GAGGGCTTAAATACATTTTT

Downstream 100 bases:

>100_bases
TATGAATGATTTGTTTACTAAAACCGATTATTCGCTTTACTCCAACTCTATGTCGTTTCTACGTCGACCGTACGTCAAAA
ACCCAGTATCGGCAGACGCA

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MRIELEKATKLDRIRADYNVHYWSQGFYGIDDQGEVYVSPRSDHAHQIPFSAIVNELEAKQLNLPVLVRFPQIVHQRVHG
ICQAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLENKQLGLEAGSKPELLAVLALAQQGSSVIVCNGYKDR
EYVRLALIGEKLGHKVFIVLEKLSELDLVLEEAKSLGVTPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLSVIDRL
KCEDQLDTMQLVHFHLGSQMANIRDVRNGVNESARFYCELRAMGANIDYFDVGGGLAVDYDGTRSQSSNSMNYGLAEYAR
NIVNTVGDVCQQYEQPMPVIISESGRSLAAHHAVLISNVIGTETYQPEEVFEPAVDAPFLLQNMWRNWENLQDGTDARAL
IEIYNDTQSDLAEVHSQFATGVLNLEQRAWAEQLSLRIYFELSRQMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
AWGIDQVFPVLPLSGLGDVEERRAVMLDITCDSDGVIDHYVDGQGIESTLPVPAWSKDKPYLMGFFLVGAYQEILGDMHN
LFGDTHSAVVNVDEEGQFEISYINEGDSVEDMMRYVHIDVDAIRDNYKQLVSARVEASEQEQILAELEQGLAGYTYLEDF

Sequences:

>Translated_640_residues
MRIELEKATKLDRIRADYNVHYWSQGFYGIDDQGEVYVSPRSDHAHQIPFSAIVNELEAKQLNLPVLVRFPQIVHQRVHG
ICQAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLENKQLGLEAGSKPELLAVLALAQQGSSVIVCNGYKDR
EYVRLALIGEKLGHKVFIVLEKLSELDLVLEEAKSLGVTPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLSVIDRL
KCEDQLDTMQLVHFHLGSQMANIRDVRNGVNESARFYCELRAMGANIDYFDVGGGLAVDYDGTRSQSSNSMNYGLAEYAR
NIVNTVGDVCQQYEQPMPVIISESGRSLAAHHAVLISNVIGTETYQPEEVFEPAVDAPFLLQNMWRNWENLQDGTDARAL
IEIYNDTQSDLAEVHSQFATGVLNLEQRAWAEQLSLRIYFELSRQMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
AWGIDQVFPVLPLSGLGDVEERRAVMLDITCDSDGVIDHYVDGQGIESTLPVPAWSKDKPYLMGFFLVGAYQEILGDMHN
LFGDTHSAVVNVDEEGQFEISYINEGDSVEDMMRYVHIDVDAIRDNYKQLVSARVEASEQEQILAELEQGLAGYTYLEDF
>Mature_640_residues
MRIELEKATKLDRIRADYNVHYWSQGFYGIDDQGEVYVSPRSDHAHQIPFSAIVNELEAKQLNLPVLVRFPQIVHQRVHG
ICQAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLENKQLGLEAGSKPELLAVLALAQQGSSVIVCNGYKDR
EYVRLALIGEKLGHKVFIVLEKLSELDLVLEEAKSLGVTPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLSVIDRL
KCEDQLDTMQLVHFHLGSQMANIRDVRNGVNESARFYCELRAMGANIDYFDVGGGLAVDYDGTRSQSSNSMNYGLAEYAR
NIVNTVGDVCQQYEQPMPVIISESGRSLAAHHAVLISNVIGTETYQPEEVFEPAVDAPFLLQNMWRNWENLQDGTDARAL
IEIYNDTQSDLAEVHSQFATGVLNLEQRAWAEQLSLRIYFELSRQMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
AWGIDQVFPVLPLSGLGDVEERRAVMLDITCDSDGVIDHYVDGQGIESTLPVPAWSKDKPYLMGFFLVGAYQEILGDMHN
LFGDTHSAVVNVDEEGQFEISYINEGDSVEDMMRYVHIDVDAIRDNYKQLVSARVEASEQEQILAELEQGLAGYTYLEDF

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=636, Percent_Identity=53.9308176100629, Blast_Score=710, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 72124; Mature: 72124

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIELEKATKLDRIRADYNVHYWSQGFYGIDDQGEVYVSPRSDHAHQIPFSAIVNELEAK
CEEECHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHH
QLNLPVLVRFPQIVHQRVHGICQAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQ
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
AQLENKQLGLEAGSKPELLAVLALAQQGSSVIVCNGYKDREYVRLALIGEKLGHKVFIVL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHEEHEEEHHHHCCEEEHHH
EKLSELDLVLEEAKSLGVTPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLSVIDRL
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KCEDQLDTMQLVHFHLGSQMANIRDVRNGVNESARFYCELRAMGANIDYFDVGGGLAVDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCCEEECCCCEEECC
DGTRSQSSNSMNYGLAEYARNIVNTVGDVCQQYEQPMPVIISESGRSLAAHHAVLISNVI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHH
GTETYQPEEVFEPAVDAPFLLQNMWRNWENLQDGTDARALIEIYNDTQSDLAEVHSQFAT
CCCCCCCHHHHCCCCCCHHHHHHHHHCHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
GVLNLEQRAWAEQLSLRIYFELSRQMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
HHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
AWGIDQVFPVLPLSGLGDVEERRAVMLDITCDSDGVIDHYVDGQGIESTLPVPAWSKDKP
CCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCC
YLMGFFLVGAYQEILGDMHNLFGDTHSAVVNVDEEGQFEISYINEGDSVEDMMRYVHIDV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHH
DAIRDNYKQLVSARVEASEQEQILAELEQGLAGYTYLEDF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MRIELEKATKLDRIRADYNVHYWSQGFYGIDDQGEVYVSPRSDHAHQIPFSAIVNELEAK
CEEECHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHH
QLNLPVLVRFPQIVHQRVHGICQAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQ
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
AQLENKQLGLEAGSKPELLAVLALAQQGSSVIVCNGYKDREYVRLALIGEKLGHKVFIVL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHEEHEEEHHHHCCEEEHHH
EKLSELDLVLEEAKSLGVTPRLGLRIRLASQGAGKWQASGGEKSKFGLSASQVLSVIDRL
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KCEDQLDTMQLVHFHLGSQMANIRDVRNGVNESARFYCELRAMGANIDYFDVGGGLAVDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCCEEECCCCEEECC
DGTRSQSSNSMNYGLAEYARNIVNTVGDVCQQYEQPMPVIISESGRSLAAHHAVLISNVI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHH
GTETYQPEEVFEPAVDAPFLLQNMWRNWENLQDGTDARALIEIYNDTQSDLAEVHSQFAT
CCCCCCCHHHHCCCCCCHHHHHHHHHCHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
GVLNLEQRAWAEQLSLRIYFELSRQMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
HHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
AWGIDQVFPVLPLSGLGDVEERRAVMLDITCDSDGVIDHYVDGQGIESTLPVPAWSKDKP
CCCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCC
YLMGFFLVGAYQEILGDMHNLFGDTHSAVVNVDEEGQFEISYINEGDSVEDMMRYVHIDV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHH
DAIRDNYKQLVSARVEASEQEQILAELEQGLAGYTYLEDF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]