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The map label for this gene is speB [H]

Identifier: 156977942

GI number: 156977942

Start: 1870458

End: 1871378

Strand: Direct

Name: speB [H]

Synonym: VIBHAR_06738

Alternate gene names: 156977942

Gene position: 1870458-1871378 (Clockwise)

Preceding gene: 156977941

Following gene: 156977943

Centisome position: 84.87

GC content: 49.29

Gene sequence:

>921_bases
ATGAATGATTTGTTTACTAAAACCGATTATTCGCTTTACTCCAACTCTATGTCGTTTCTACGTCGACCGTACGTCAAAAA
CCCAGTATCGGCAGACGCAGACGTTGTGGTGCTCGGGGTTCCTCTGGACATGGCGACTTCTGGTCGTCCTGGTGCGCGTA
TGGGTCCAGATGCGATCCGCCGTGCGTCAGTAAACCTTGCTTGGGAAGGCAAGAAGTTCCCTTGGGACTTCAACGTATTT
GATAAATTGAAAGTGATCGACGCAGGTGACCTTGTGTTCGATTGTGGTGATGCTGAAGATTTCACTTACCGCCTAGAAGC
GGCAACAAGTGAGATTCTAAAGAGCGGTAAGACAATGCTAGGCTTGGGTGGTGACCACTTTATCACGCTACCAATCCTAC
GTGCTTACGCGAAGCACCATGGTCAAATGGCACTGATTCACTTCGATGCGCACACAGACACTTACGCAAATGGCAGTTCT
TACGACCACGGTACTATGTTCTACCATGCGCCAAAAGAAGGCCTGATCTCTGCGAAGAACTCAGTTCAAATTGGTATTCG
TACTGAATATGACCAACAAGATCACGGCTTCAATGTGATCAACGCGATGCAAGCGAACGACATGTCGGTAGAAGAGATTC
TGGCAGAAATCCGTCGCACGGTTGCGGATAAGCCTGTGTATGTCACGTTTGACATCGACTGTCTGGATCCTGCGTTTGCA
CCGGGTACAGGTACACCAGTTTGTGGTGGCCTGAACTCAGATAAAATTCTGAAGATCATTCGTGGTTTCGCAGGCATGAA
TATCGTAGGTATGGACGTGGTGGAAGTCTCTCCTCCTTACGACCACAGCGATGTGACGGCCTTGGCTGGCGCGACTATCG
CACTTGAGTTGCTTTACGCCTACGCTTCAGGTCGCGAATAA

Upstream 100 bases:

>100_bases
CAATTGGTTTCAGCACGTGTTGAAGCCAGTGAACAAGAACAAATCCTAGCTGAACTAGAACAAGGTTTGGCAGGCTACAC
CTATTTAGAGGACTTCTGAT

Downstream 100 bases:

>100_bases
CGAAAGTTGTTCTAAACAAACGCAAGATTTCAAAGGGAGCTTCGGCTCCCTTTTTCGTTTTCAACACCCAACAAAATTGG
ATTAGATTTTCTAATCCAAG

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNDLFTKTDYSLYSNSMSFLRRPYVKNPVSADADVVVLGVPLDMATSGRPGARMGPDAIRRASVNLAWEGKKFPWDFNVF
DKLKVIDAGDLVFDCGDAEDFTYRLEAATSEILKSGKTMLGLGGDHFITLPILRAYAKHHGQMALIHFDAHTDTYANGSS
YDHGTMFYHAPKEGLISAKNSVQIGIRTEYDQQDHGFNVINAMQANDMSVEEILAEIRRTVADKPVYVTFDIDCLDPAFA
PGTGTPVCGGLNSDKILKIIRGFAGMNIVGMDVVEVSPPYDHSDVTALAGATIALELLYAYASGRE

Sequences:

>Translated_306_residues
MNDLFTKTDYSLYSNSMSFLRRPYVKNPVSADADVVVLGVPLDMATSGRPGARMGPDAIRRASVNLAWEGKKFPWDFNVF
DKLKVIDAGDLVFDCGDAEDFTYRLEAATSEILKSGKTMLGLGGDHFITLPILRAYAKHHGQMALIHFDAHTDTYANGSS
YDHGTMFYHAPKEGLISAKNSVQIGIRTEYDQQDHGFNVINAMQANDMSVEEILAEIRRTVADKPVYVTFDIDCLDPAFA
PGTGTPVCGGLNSDKILKIIRGFAGMNIVGMDVVEVSPPYDHSDVTALAGATIALELLYAYASGRE
>Mature_306_residues
MNDLFTKTDYSLYSNSMSFLRRPYVKNPVSADADVVVLGVPLDMATSGRPGARMGPDAIRRASVNLAWEGKKFPWDFNVF
DKLKVIDAGDLVFDCGDAEDFTYRLEAATSEILKSGKTMLGLGGDHFITLPILRAYAKHHGQMALIHFDAHTDTYANGSS
YDHGTMFYHAPKEGLISAKNSVQIGIRTEYDQQDHGFNVINAMQANDMSVEEILAEIRRTVADKPVYVTFDIDCLDPAFA
PGTGTPVCGGLNSDKILKIIRGFAGMNIVGMDVVEVSPPYDHSDVTALAGATIALELLYAYASGRE

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=293, Percent_Identity=44.7098976109215, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI10947139, Length=309, Percent_Identity=26.2135922330097, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4502215, Length=307, Percent_Identity=25.7328990228013, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789306, Length=305, Percent_Identity=60, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6325146, Length=232, Percent_Identity=25, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33432; Mature: 33432

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLFTKTDYSLYSNSMSFLRRPYVKNPVSADADVVVLGVPLDMATSGRPGARMGPDAIR
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RASVNLAWEGKKFPWDFNVFDKLKVIDAGDLVFDCGDAEDFTYRLEAATSEILKSGKTML
HCCEEEEECCCCCCCCCCHHHEEEEEECCCEEEECCCCCCEEEEEHHHHHHHHHCCCEEE
GLGGDHFITLPILRAYAKHHGQMALIHFDAHTDTYANGSSYDHGTMFYHAPKEGLISAKN
ECCCCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEECCC
SVQIGIRTEYDQQDHGFNVINAMQANDMSVEEILAEIRRTVADKPVYVTFDIDCLDPAFA
CEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLNSDKILKIIRGFAGMNIVGMDVVEVSPPYDHSDVTALAGATIALELLYA
CCCCCCEECCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
YASGRE
HHCCCC
>Mature Secondary Structure
MNDLFTKTDYSLYSNSMSFLRRPYVKNPVSADADVVVLGVPLDMATSGRPGARMGPDAIR
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RASVNLAWEGKKFPWDFNVFDKLKVIDAGDLVFDCGDAEDFTYRLEAATSEILKSGKTML
HCCEEEEECCCCCCCCCCHHHEEEEEECCCEEEECCCCCCEEEEEHHHHHHHHHCCCEEE
GLGGDHFITLPILRAYAKHHGQMALIHFDAHTDTYANGSSYDHGTMFYHAPKEGLISAKN
ECCCCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEECCC
SVQIGIRTEYDQQDHGFNVINAMQANDMSVEEILAEIRRTVADKPVYVTFDIDCLDPAFA
CEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLNSDKILKIIRGFAGMNIVGMDVVEVSPPYDHSDVTALAGATIALELLYA
CCCCCCEECCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
YASGRE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]