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The map label for this gene is fruK [H]

Identifier: 156977173

GI number: 156977173

Start: 1146161

End: 1147135

Strand: Direct

Name: fruK [H]

Synonym: VIBHAR_05959

Alternate gene names: 156977173

Gene position: 1146161-1147135 (Clockwise)

Preceding gene: 156977172

Following gene: 156977174

Centisome position: 52.0

GC content: 49.33

Gene sequence:

>975_bases
ATGACAGCATTGAAAACAAACAAAGTCGTTACCATCACGCTTAACCCTGCCCTTGATCTAACAGGTTCGCTGGACTCAAT
TAAAGTGGGTTCTGTCAGCCTAGTTGAAAAGAGCAACCTACACGCAGCCGGTAAAGGCGTAAACGTAGCGAAAGTGCTTA
GTGACCTAGGTTCAGACGTAACAGTGACGGGCTTTCTTGGCAAAGACAACTCTGAGCTGTTCCACCAGCTATTTAGCGAT
ATCAATGTTAAAAACGAGTTCGTTGAAGTCGAAGGCGCAACTCGCATCAACGTGAAATTGGTTGAAGCCGATGGCCAAGT
CAGCGACATCAACTTCCCTGGCGTTCAAGTTAGGACAGAAGAAATCGCGCGCTTTGAAGAAACCCTATTCCGCCTTGCAG
AAACACACGATTACTTCGTATTGGCAGGCAGCCTACCGGGCGGCGTTACCGCAGAGCAATGCGCGGCATGGATTGAAAAG
CTGCATCAGCAAGGTAAGAAAGTTTTGTTCGATAGCAGCAAAGCAGCACTACGCGCAGGCATCGACGCTCATCCTTGGTT
GATCAAACCAAACGACGAAGAGTTAAGTGACTTTGTCGGCGAGCACCTTTCAACGCCAGAACAATGCCAAGAAGCAGCGC
AAACGCTAAGCGATAAAGGCATTGAGAACATCGTGGTTTCTATGGGTGCAGACGGAGTGATGTGGCTGAACCAAGGTGAA
TGGCTTCGCGCACAACCACCACGAATGAATGTTGTAAGCACCGTTGGCGCAGGCGATACGCTTGTGGCTGGCTTGTGCTG
GGGTCACATGCAAGTGATGCCGAAAAACGATTTACTGCGCTTCGCTACGGCGCTTTCTGCCCTAGCAGTGAGCCAAGTTG
GCGTTGGCCTAACCAGTCAGGAAGAACTGGAGAACATTAAGCTCCAAACCGAAGTTACCGAGCTTTACCCTAATACGAAC
TTAGACAAAAACTAA

Upstream 100 bases:

>100_bases
AGCTTCAATTCTCTGCTGAAGGTCCAGATGCTGCACAAGCGCTTGAGTCAATCGGCAAAGCAATCGCATCTGGTCTTGGC
GAAGGTTAAGGGGCGTGAGA

Downstream 100 bases:

>100_bases
GGAACAGAAGGTTATCAGTATGAATATTGCCATTATTACAGCTTGTCCAAGTGGTGTTGCGAACAGCATCATTGCGGCAG
GCCTACTAGAACAAGCAGCA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTALKTNKVVTITLNPALDLTGSLDSIKVGSVSLVEKSNLHAAGKGVNVAKVLSDLGSDVTVTGFLGKDNSELFHQLFSD
INVKNEFVEVEGATRINVKLVEADGQVSDINFPGVQVRTEEIARFEETLFRLAETHDYFVLAGSLPGGVTAEQCAAWIEK
LHQQGKKVLFDSSKAALRAGIDAHPWLIKPNDEELSDFVGEHLSTPEQCQEAAQTLSDKGIENIVVSMGADGVMWLNQGE
WLRAQPPRMNVVSTVGAGDTLVAGLCWGHMQVMPKNDLLRFATALSALAVSQVGVGLTSQEELENIKLQTEVTELYPNTN
LDKN

Sequences:

>Translated_324_residues
MTALKTNKVVTITLNPALDLTGSLDSIKVGSVSLVEKSNLHAAGKGVNVAKVLSDLGSDVTVTGFLGKDNSELFHQLFSD
INVKNEFVEVEGATRINVKLVEADGQVSDINFPGVQVRTEEIARFEETLFRLAETHDYFVLAGSLPGGVTAEQCAAWIEK
LHQQGKKVLFDSSKAALRAGIDAHPWLIKPNDEELSDFVGEHLSTPEQCQEAAQTLSDKGIENIVVSMGADGVMWLNQGE
WLRAQPPRMNVVSTVGAGDTLVAGLCWGHMQVMPKNDLLRFATALSALAVSQVGVGLTSQEELENIKLQTEVTELYPNTN
LDKN
>Mature_323_residues
TALKTNKVVTITLNPALDLTGSLDSIKVGSVSLVEKSNLHAAGKGVNVAKVLSDLGSDVTVTGFLGKDNSELFHQLFSDI
NVKNEFVEVEGATRINVKLVEADGQVSDINFPGVQVRTEEIARFEETLFRLAETHDYFVLAGSLPGGVTAEQCAAWIEKL
HQQGKKVLFDSSKAALRAGIDAHPWLIKPNDEELSDFVGEHLSTPEQCQEAAQTLSDKGIENIVVSMGADGVMWLNQGEW
LRAQPPRMNVVSTVGAGDTLVAGLCWGHMQVMPKNDLLRFATALSALAVSQVGVGLTSQEELENIKLQTEVTELYPNTNL
DKN

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=299, Percent_Identity=49.1638795986622, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1788017, Length=302, Percent_Identity=29.8013245033113, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 35024; Mature: 34893

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALKTNKVVTITLNPALDLTGSLDSIKVGSVSLVEKSNLHAAGKGVNVAKVLSDLGSDV
CCCCCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECCCCCCCCCCCHHHHHHHHCCCCE
TVTGFLGKDNSELFHQLFSDINVKNEFVEVEGATRINVKLVEADGQVSDINFPGVQVRTE
EEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEECCCCEEECCCCCCEEEHH
EIARFEETLFRLAETHDYFVLAGSLPGGVTAEQCAAWIEKLHQQGKKVLFDSSKAALRAG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHCC
IDAHPWLIKPNDEELSDFVGEHLSTPEQCQEAAQTLSDKGIENIVVSMGADGVMWLNQGE
CCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHEEEECCCCCEEEECCCC
WLRAQPPRMNVVSTVGAGDTLVAGLCWGHMQVMPKNDLLRFATALSALAVSQVGVGLTSQ
EEECCCCCCCEEEECCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCH
EELENIKLQTEVTELYPNTNLDKN
HHHHHEEHEEHHHHHCCCCCCCCC
>Mature Secondary Structure 
TALKTNKVVTITLNPALDLTGSLDSIKVGSVSLVEKSNLHAAGKGVNVAKVLSDLGSDV
CCCCCCCEEEEEECCCCCCCCCCCCEEECCEEEEECCCCCCCCCCCHHHHHHHHCCCCE
TVTGFLGKDNSELFHQLFSDINVKNEFVEVEGATRINVKLVEADGQVSDINFPGVQVRTE
EEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEECCCCEEECCCCCCEEEHH
EIARFEETLFRLAETHDYFVLAGSLPGGVTAEQCAAWIEKLHQQGKKVLFDSSKAALRAG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHCC
IDAHPWLIKPNDEELSDFVGEHLSTPEQCQEAAQTLSDKGIENIVVSMGADGVMWLNQGE
CCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHEEEECCCCCEEEECCCC
WLRAQPPRMNVVSTVGAGDTLVAGLCWGHMQVMPKNDLLRFATALSALAVSQVGVGLTSQ
EEECCCCCCCEEEECCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCH
EELENIKLQTEVTELYPNTNLDKN
HHHHHEEHEEHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]