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The map label for this gene is cyoB [H]

Identifier: 156976717

GI number: 156976717

Start: 703416

End: 705452

Strand: Direct

Name: cyoB [H]

Synonym: VIBHAR_05492

Alternate gene names: 156976717

Gene position: 703416-705452 (Clockwise)

Preceding gene: 156976716

Following gene: 156976718

Centisome position: 31.92

GC content: 48.8

Gene sequence:

>2037_bases
ATGTTTGGAAGATTAACACTTGAATCAATCCCTTATCACGAGCCGATTATCGTCGTCACTCTAGCGGTGATCGCGATCGT
TGGTTTGGCTGTCGTTGCGGCGATAACCAAAGCGGGTAAGTGGCAATACTTATGGAATGAATGGTTTACTTCAGTAGACC
ACAAAAAATTAGGCTTTATGTACATCGCTGTGGCAATGGTGATGTTGATTCGTGGCTTTGCTGATGCGGTCATGATGCGT
AGCCAACAGCTGCTTTCTGCGGCAGGTGAGACCGGTTATCTACCACCACATCACTACGATCAAATCTTTACTGCCCACGG
CGTAATCATGATTTTCTTCGTGGCGATGCCGTTGGTTATTGGTTTGATGAACATCATCGTACCGCTGCAAATTGGTGCGC
GTGACGTGGCATTCCCTTACTTAAACAACCTGAGTTTCTGGTTGTTTGTTGTGGGTGTGATCCTAACCAACATGTCACTT
GGCTTAGGTGAGTTTGGTCGTACTGGTTGGTTGGCGTATCCGCCACTGTCTGGTATCGAAGCAAGCCCAGGAGTCGGGGT
AGACTATTGGATATGGGCACTGCAAATATCTGGTGTGGGTACCACGCTGACGGGCGTGAACTTCTTCGCAACCATCTTGC
GCATGCGTACACCGTCTATGCCAATGATGAAGATGCCAGTGTTCACGTGGGCGTCCCTGTGTGCCAACATCCTAATCATT
ATTTCATTCCCAATCCTTACGGTAACCATCGCGCTACTGACATTGGATCGCTACATCGGTACACACTTCTTCACCAATGA
TCTTGGTGGCAACGTAATGATGTACGTGAACTTGATTTGGGCATGGGGTCACCCAGAAGTATACATCTTGATCTTGCCTA
TCTTTGGTGTGTTCTCTGAAGTAACCGCAACGTTCTCACGCAAGAAACTGTTTGGTTATACCTCTCTAGTATGGGCGACC
ATCGTTATTACGATTTTGGCGTTCGTCGTTTGGCTGCATCACTTCTTCACCATGGGCTCAGGTGCGAATGTGAATGCGTT
CTTCGGCATCGCCACCATGATTATCTCTATCCCTACCGGGGTGAAGATCTTCAACTGGCTATTCACCATGTACAAAGGTC
GAATCCGCTTTACCACTCCGATGATGTGGACGGTTGGCTTCCTAATTACCTTCTCTGTAGGTGGTATGACGGGCGTACTA
ATGGCAGTGCCAGGCGCGGACTTTGTTCTGCACAACTCAGTGTTCCTGATTGCGCACTTCCATAACGTAATCATCGGTGG
TGTGGTATTCGGTTGTTTCGCTGCAATCACATACTGGTTCCCGAAAGCAACTGGCTTCACCATGAACGAAACATGGGGCA
AACGTGCATTCATTTGCTGGATTGTCGGTTTCCTAATGGCGTTCCTACCACTGTACGCGCTGGGCTTTATGGGTATGACG
CGTCGTCTAAGCCAAGATCTGAACCCAGAGTACTTCCCACTGTTGGCAGTTGCCGCAGCGGGTACGGCAGTGATTGCGCT
TGGCGTGGCTTGTCAGTTCATTCAAATCTACGTGAGTGTTCGTGACCGTGAGCAAAACCGTGACCTAACGGGTGACCCGT
GGGGCGGTCGTACTTTCGAGTGGGCGACTTCTTCACCACCGCCGTTCTACAACTTCGCGCACCTACCAAAAGGCGACGTT
CTAGATGGGTTCTGGTACCAAAAACAGAGTGGCGAATTCGATCCAACCAAAGAAGTGGAATACGAGCGTATCCATATGCC
GAAGAACACACCAACAGGTATCTACGTATCTGCATGGGCATTGGTGTTTGGCTTCGCGATGATTTGGTACATCTGGTGGC
TAGCAGCAGCAAGCTTTGTTGGCATCATCGTGACTTGTATTCAACACAGCTACAACGACGATGTGGATTACTACGTTGAA
GTTGAAGAAATCAAAGCGATTGAAGCGGAGCGTCGAGCTCAACTTGAAGAAGCGAAGAAAAACGAAGTGAAAGACAACGA
GAAAAAAGACGATCTGGAGGTGACGTATGCAAGCTAA

Upstream 100 bases:

>100_bases
TGAAGCTGTTCTCTAGCGTTCCACCATTTTTGTTCACCGACGTCGTGACCCAGCATCCGGGTTCAATGAACTGCTTGCCG
GAAAATCTAGGATAACCGCA

Downstream 100 bases:

>100_bases
TGTAGCCGCTCACGAGCACGATCATCACCATGACTCGGCCGGCAACAAGTTGTTTGGTTTCTGGGTTTACCTAATGAGTG
ACTGTGTATTGTTTGCGACC

Product: cytochrome o ubiquinol oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MFGRLTLESIPYHEPIIVVTLAVIAIVGLAVVAAITKAGKWQYLWNEWFTSVDHKKLGFMYIAVAMVMLIRGFADAVMMR
SQQLLSAAGETGYLPPHHYDQIFTAHGVIMIFFVAMPLVIGLMNIIVPLQIGARDVAFPYLNNLSFWLFVVGVILTNMSL
GLGEFGRTGWLAYPPLSGIEASPGVGVDYWIWALQISGVGTTLTGVNFFATILRMRTPSMPMMKMPVFTWASLCANILII
ISFPILTVTIALLTLDRYIGTHFFTNDLGGNVMMYVNLIWAWGHPEVYILILPIFGVFSEVTATFSRKKLFGYTSLVWAT
IVITILAFVVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYKGRIRFTTPMMWTVGFLITFSVGGMTGVL
MAVPGADFVLHNSVFLIAHFHNVIIGGVVFGCFAAITYWFPKATGFTMNETWGKRAFICWIVGFLMAFLPLYALGFMGMT
RRLSQDLNPEYFPLLAVAAAGTAVIALGVACQFIQIYVSVRDREQNRDLTGDPWGGRTFEWATSSPPPFYNFAHLPKGDV
LDGFWYQKQSGEFDPTKEVEYERIHMPKNTPTGIYVSAWALVFGFAMIWYIWWLAAASFVGIIVTCIQHSYNDDVDYYVE
VEEIKAIEAERRAQLEEAKKNEVKDNEKKDDLEVTYAS

Sequences:

>Translated_678_residues
MFGRLTLESIPYHEPIIVVTLAVIAIVGLAVVAAITKAGKWQYLWNEWFTSVDHKKLGFMYIAVAMVMLIRGFADAVMMR
SQQLLSAAGETGYLPPHHYDQIFTAHGVIMIFFVAMPLVIGLMNIIVPLQIGARDVAFPYLNNLSFWLFVVGVILTNMSL
GLGEFGRTGWLAYPPLSGIEASPGVGVDYWIWALQISGVGTTLTGVNFFATILRMRTPSMPMMKMPVFTWASLCANILII
ISFPILTVTIALLTLDRYIGTHFFTNDLGGNVMMYVNLIWAWGHPEVYILILPIFGVFSEVTATFSRKKLFGYTSLVWAT
IVITILAFVVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYKGRIRFTTPMMWTVGFLITFSVGGMTGVL
MAVPGADFVLHNSVFLIAHFHNVIIGGVVFGCFAAITYWFPKATGFTMNETWGKRAFICWIVGFLMAFLPLYALGFMGMT
RRLSQDLNPEYFPLLAVAAAGTAVIALGVACQFIQIYVSVRDREQNRDLTGDPWGGRTFEWATSSPPPFYNFAHLPKGDV
LDGFWYQKQSGEFDPTKEVEYERIHMPKNTPTGIYVSAWALVFGFAMIWYIWWLAAASFVGIIVTCIQHSYNDDVDYYVE
VEEIKAIEAERRAQLEEAKKNEVKDNEKKDDLEVTYAS
>Mature_678_residues
MFGRLTLESIPYHEPIIVVTLAVIAIVGLAVVAAITKAGKWQYLWNEWFTSVDHKKLGFMYIAVAMVMLIRGFADAVMMR
SQQLLSAAGETGYLPPHHYDQIFTAHGVIMIFFVAMPLVIGLMNIIVPLQIGARDVAFPYLNNLSFWLFVVGVILTNMSL
GLGEFGRTGWLAYPPLSGIEASPGVGVDYWIWALQISGVGTTLTGVNFFATILRMRTPSMPMMKMPVFTWASLCANILII
ISFPILTVTIALLTLDRYIGTHFFTNDLGGNVMMYVNLIWAWGHPEVYILILPIFGVFSEVTATFSRKKLFGYTSLVWAT
IVITILAFVVWLHHFFTMGSGANVNAFFGIATMIISIPTGVKIFNWLFTMYKGRIRFTTPMMWTVGFLITFSVGGMTGVL
MAVPGADFVLHNSVFLIAHFHNVIIGGVVFGCFAAITYWFPKATGFTMNETWGKRAFICWIVGFLMAFLPLYALGFMGMT
RRLSQDLNPEYFPLLAVAAAGTAVIALGVACQFIQIYVSVRDREQNRDLTGDPWGGRTFEWATSSPPPFYNFAHLPKGDV
LDGFWYQKQSGEFDPTKEVEYERIHMPKNTPTGIYVSAWALVFGFAMIWYIWWLAAASFVGIIVTCIQHSYNDDVDYYVE
VEEIKAIEAERRAQLEEAKKNEVKDNEKKDDLEVTYAS

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=36.986301369863, Blast_Score=328, Evalue=9e-90,
Organism=Escherichia coli, GI1786634, Length=667, Percent_Identity=72.7136431784108, Blast_Score=1028, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=36.4312267657993, Blast_Score=317, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6226524, Length=326, Percent_Identity=41.7177914110429, Blast_Score=234, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=34.2629482071713, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 76045; Mature: 76045

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGRLTLESIPYHEPIIVVTLAVIAIVGLAVVAAITKAGKWQYLWNEWFTSVDHKKLGFM
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHH
YIAVAMVMLIRGFADAVMMRSQQLLSAAGETGYLPPHHYDQIFTAHGVIMIFFVAMPLVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNIIVPLQIGARDVAFPYLNNLSFWLFVVGVILTNMSLGLGEFGRTGWLAYPPLSGIE
HHHHHHHHHCCCCCHHCCHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCC
ASPGVGVDYWIWALQISGVGTTLTGVNFFATILRMRTPSMPMMKMPVFTWASLCANILII
CCCCCCHHEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ISFPILTVTIALLTLDRYIGTHFFTNDLGGNVMMYVNLIWAWGHPEVYILILPIFGVFSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEEHHHHHHHH
VTATFSRKKLFGYTSLVWATIVITILAFVVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYKGRIRFTTPMMWTVGFLITFSVGGMTGVLMAVPGADFVLHNSVFLIAHF
HHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCHHEEEEECCCCCEEEECCEEEEHHH
HNVIIGGVVFGCFAAITYWFPKATGFTMNETWGKRAFICWIVGFLMAFLPLYALGFMGMT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQDLNPEYFPLLAVAAAGTAVIALGVACQFIQIYVSVRDREQNRDLTGDPWGGRTFE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WATSSPPPFYNFAHLPKGDVLDGFWYQKQSGEFDPTKEVEYERIHMPKNTPTGIYVSAWA
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHEEECCCCCCCCHHHHHHH
LVFGFAMIWYIWWLAAASFVGIIVTCIQHSYNDDVDYYVEVEEIKAIEAERRAQLEEAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
NEVKDNEKKDDLEVTYAS
HCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MFGRLTLESIPYHEPIIVVTLAVIAIVGLAVVAAITKAGKWQYLWNEWFTSVDHKKLGFM
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHH
YIAVAMVMLIRGFADAVMMRSQQLLSAAGETGYLPPHHYDQIFTAHGVIMIFFVAMPLVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNIIVPLQIGARDVAFPYLNNLSFWLFVVGVILTNMSLGLGEFGRTGWLAYPPLSGIE
HHHHHHHHHCCCCCHHCCHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCC
ASPGVGVDYWIWALQISGVGTTLTGVNFFATILRMRTPSMPMMKMPVFTWASLCANILII
CCCCCCHHEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
ISFPILTVTIALLTLDRYIGTHFFTNDLGGNVMMYVNLIWAWGHPEVYILILPIFGVFSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEEHHHHHHHH
VTATFSRKKLFGYTSLVWATIVITILAFVVWLHHFFTMGSGANVNAFFGIATMIISIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VKIFNWLFTMYKGRIRFTTPMMWTVGFLITFSVGGMTGVLMAVPGADFVLHNSVFLIAHF
HHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCHHEEEEECCCCCEEEECCEEEEHHH
HNVIIGGVVFGCFAAITYWFPKATGFTMNETWGKRAFICWIVGFLMAFLPLYALGFMGMT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQDLNPEYFPLLAVAAAGTAVIALGVACQFIQIYVSVRDREQNRDLTGDPWGGRTFE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
WATSSPPPFYNFAHLPKGDVLDGFWYQKQSGEFDPTKEVEYERIHMPKNTPTGIYVSAWA
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHEEECCCCCCCCHHHHHHH
LVFGFAMIWYIWWLAAASFVGIIVTCIQHSYNDDVDYYVEVEEIKAIEAERRAQLEEAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
NEVKDNEKKDDLEVTYAS
HCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]