Click here to switch to the map view.

The map label for this gene is appB [H]

Identifier: 156938123

GI number: 156938123

Start: 1188624

End: 1189682

Strand: Direct

Name: appB [H]

Synonym: Igni_1336

Alternate gene names: 156938123

Gene position: 1188624-1189682 (Clockwise)

Preceding gene: 156938121

Following gene: 156938124

Centisome position: 91.61

GC content: 52.79

Gene sequence:

>1059_bases
TTGGGCCTCAAGTATAACAAGCAGTTGACCTTGAAGGTGGCGAGCCGCCTAGCAGATGCGGCTCTGGTCTTGTTAATAGT
CCTAATAATCACTGTGGCTATGTTTGGAGGTCTCATAGCGGAGATCAAGAAGCAGATGATAGAGGACGAGGTAAAGAGGT
GGGTGATGAGTCAGCCCCAACTGGTCCAGAAGCTGGGAGAGAAAGTTAAGGATTTCATAAAGGAACAAGTGGAAGAGAGG
ATCAAGGCCGAGGGCCTCGACAAGCCGTGGTACGCTAACTTGCTCTATTACTTGTCTACCGTAGTAACGTTAGACATGAG
GAGCCACGTGCTCCGCTCTAATACCGGCTCCCAGCTGGTTAAAGACATTATAATGGAAAGGCTCCCGAGGACCGTGCTCT
TGTTTACGACCGCCACAGTGATCTCAGCCCTCATTGGAATACTGTTAGGGTTGGTGGCGGCCTACAAGAGGGGGAGCGTC
GTGGACAAGCTGGTGACTGTGGCCGCTCTAATTTCAGCTAGCTTTCCCATGTGGTGGATCGGCATGATCATGATAGAAGT
ATTCTCGTACGCGTTGGGGGTTTTCCCCTCCGGAGGCATGACCAGCGTGCCCCCTCCCAGCGACCCGATCGCTTACGTGG
CCGACGTGCTCTACCACATGTCACTCCCGCTGTTAACCATAGTGTTGGTAAGTGTGGGCGGGTGGGCTTACGTCACTAGG
AGCATCTTGGTGGGGGCTACAAAGGAGGACTTCGTCTTGGCCGCCAAGGCCAGAGGGCTCGCGGAGAGGACGGTCCTCTT
AAGGCACGTGTTGAGGCCTTCGATACCCCCAATCCTAACTATGATAGCCTTGAGCTTGGTCGCCTCTTTGAGCGGAGCCA
TAATCACCGAGATAGTGTTCAACTGGCCCGGCATGGGGCTGCTCTACTGGGAGGCGATAGAGACCCTCGACGTTCCCGTC
ATACTCGGCTTGACGTACATATTTACGTTAGTTTTCGTAATAGCTATGGTAATATTAGATGTGATGTACATAGTCTTAGA
TCCTAGGGTGAGGTGGTGA

Upstream 100 bases:

>100_bases
ATTGTTGGAAAAGCTCCCGCTGATTATATTTATTTTAAGCATGGCCATAACTGTGTTCGCGCCTCAGTACTCCGTACCCC
TTTGGTTGCTCCTCTTTGCC

Downstream 100 bases:

>100_bases
AGGGCTTTGAACGAGTTCTTGAAGGAGCTGTTGTCCCAGAGCTCCGGCCTCTTCGGTACGCTAACCTTTGTCGTGTTGTT
GGCGCTGGCCCTCTACTCGT

Product: binding-protein-dependent transporters inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGLKYNKQLTLKVASRLADAALVLLIVLIITVAMFGGLIAEIKKQMIEDEVKRWVMSQPQLVQKLGEKVKDFIKEQVEER
IKAEGLDKPWYANLLYYLSTVVTLDMRSHVLRSNTGSQLVKDIIMERLPRTVLLFTTATVISALIGILLGLVAAYKRGSV
VDKLVTVAALISASFPMWWIGMIMIEVFSYALGVFPSGGMTSVPPPSDPIAYVADVLYHMSLPLLTIVLVSVGGWAYVTR
SILVGATKEDFVLAAKARGLAERTVLLRHVLRPSIPPILTMIALSLVASLSGAIITEIVFNWPGMGLLYWEAIETLDVPV
ILGLTYIFTLVFVIAMVILDVMYIVLDPRVRW

Sequences:

>Translated_352_residues
MGLKYNKQLTLKVASRLADAALVLLIVLIITVAMFGGLIAEIKKQMIEDEVKRWVMSQPQLVQKLGEKVKDFIKEQVEER
IKAEGLDKPWYANLLYYLSTVVTLDMRSHVLRSNTGSQLVKDIIMERLPRTVLLFTTATVISALIGILLGLVAAYKRGSV
VDKLVTVAALISASFPMWWIGMIMIEVFSYALGVFPSGGMTSVPPPSDPIAYVADVLYHMSLPLLTIVLVSVGGWAYVTR
SILVGATKEDFVLAAKARGLAERTVLLRHVLRPSIPPILTMIALSLVASLSGAIITEIVFNWPGMGLLYWEAIETLDVPV
ILGLTYIFTLVFVIAMVILDVMYIVLDPRVRW
>Mature_351_residues
GLKYNKQLTLKVASRLADAALVLLIVLIITVAMFGGLIAEIKKQMIEDEVKRWVMSQPQLVQKLGEKVKDFIKEQVEERI
KAEGLDKPWYANLLYYLSTVVTLDMRSHVLRSNTGSQLVKDIIMERLPRTVLLFTTATVISALIGILLGLVAAYKRGSVV
DKLVTVAALISASFPMWWIGMIMIEVFSYALGVFPSGGMTSVPPPSDPIAYVADVLYHMSLPLLTIVLVSVGGWAYVTRS
ILVGATKEDFVLAAKARGLAERTVLLRHVLRPSIPPILTMIALSLVASLSGAIITEIVFNWPGMGLLYWEAIETLDVPVI
LGLTYIFTLVFVIAMVILDVMYIVLDPRVRW

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=278, Percent_Identity=33.4532374100719, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789965, Length=301, Percent_Identity=28.9036544850498, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787761, Length=300, Percent_Identity=29.3333333333333, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788504, Length=282, Percent_Identity=26.9503546099291, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789888, Length=267, Percent_Identity=28.8389513108614, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787497, Length=288, Percent_Identity=23.9583333333333, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787550, Length=253, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38944; Mature: 38813

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKYNKQLTLKVASRLADAALVLLIVLIITVAMFGGLIAEIKKQMIEDEVKRWVMSQPQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQKLGEKVKDFIKEQVEERIKAEGLDKPWYANLLYYLSTVVTLDMRSHVLRSNTGSQLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KDIIMERLPRTVLLFTTATVISALIGILLGLVAAYKRGSVVDKLVTVAALISASFPMWWI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHH
GMIMIEVFSYALGVFPSGGMTSVPPPSDPIAYVADVLYHMSLPLLTIVLVSVGGWAYVTR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SILVGATKEDFVLAAKARGLAERTVLLRHVLRPSIPPILTMIALSLVASLSGAIITEIVF
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NWPGMGLLYWEAIETLDVPVILGLTYIFTLVFVIAMVILDVMYIVLDPRVRW
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GLKYNKQLTLKVASRLADAALVLLIVLIITVAMFGGLIAEIKKQMIEDEVKRWVMSQPQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQKLGEKVKDFIKEQVEERIKAEGLDKPWYANLLYYLSTVVTLDMRSHVLRSNTGSQLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KDIIMERLPRTVLLFTTATVISALIGILLGLVAAYKRGSVVDKLVTVAALISASFPMWWI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHH
GMIMIEVFSYALGVFPSGGMTSVPPPSDPIAYVADVLYHMSLPLLTIVLVSVGGWAYVTR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SILVGATKEDFVLAAKARGLAERTVLLRHVLRPSIPPILTMIALSLVASLSGAIITEIVF
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NWPGMGLLYWEAIETLDVPVILGLTYIFTLVFVIAMVILDVMYIVLDPRVRW
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]