Click here to switch to the map view.

The map label for this gene is 156937718

Identifier: 156937718

GI number: 156937718

Start: 820934

End: 822037

Strand: Direct

Name: 156937718

Synonym: Igni_0927

Alternate gene names: NA

Gene position: 820934-822037 (Clockwise)

Preceding gene: 156937715

Following gene: 156937720

Centisome position: 63.27

GC content: 58.79

Gene sequence:

>1104_bases
TTGGACGCCGGGGTGGAGCCCGGCGTGGACAAGGTAATCTTGACCCACGCCCACTTGGACCACAGCTTAATGGCCCCTGG
CAAGGAGGTCTACGCCACGCTCCCAACGCTTGCCTTGGCAAAGGAGTTGTGGTTGGACGCCAAGTCCCTCAACCCGGACC
TCCCTTGGGAGGCGACTGACGTCCAGAAGACCTTGAACTCGTCCTTCCGGGTGCCTTACGGGAGACCCTTCAAGGTAGGG
GATGCGACGGTCACTCTGTTCAACGCGGGCCACGTGTTGGGGAGCGCGATGGTGTTGGTGGAGTGTGAGGGGAAGAGGCT
CCTCTACACCGGCGACTTGGGGACCTCGAGCTTCTTGCTAGACCACTGGTCGAAGGAGGTGCCACAGGCGGACGTGTTGG
TGACGGAGAGCAGCTACTTGTGTAAGGATAGACCATCTGCGAAGAAGGAGTGGTCGAGGCTCTTGTACTTCTTAAAGCAG
AGGCTGCGGGAGGGGCCGGTGCTGATAGCGGCCAACGCAGTGGGAAAGGTTCAAGAGGTCATTAAGTTTCTTATGAACTA
TAAAGAACAGATAGGGTTGAATGCAGTCATAGTCGAGGGTATGGGCTTCCGCGCTACGAAGATATACGACGAAATGATTG
AGTATTTGAAGGAAAGCGAGGTGACGGCGTGGTTGAACGGGAACAGGAGGAGGCTAACGGACTTCGTAACTTTCCCGTCT
TCTTTAAGAGAGAGGTTGGACATGGCGAGGCCCGGCACGGCGGTGGTCGCGCCTTCCGGCTCCCTGAGCGGGGGCATGAG
CGTCTGGTGGGCGCTCAAGGGGGTGCCGTACGTCTTGTTGGGCCACGTGTTCGAGCCGGCCTCCTCCCTCCTAGCGGGCG
GGGAGGTAACGTTGAAGGACCCCTTGGGCAACGAGGGCGTCGTGAGGCCGCCGGAGCTGCACTTGCAGATCTCCAGGCAC
GCGACGAGGCAAGAGCTCTTGCAATTTATCTCCCTTACAAAGGCCAAGGAAGTCTACTTGGTCCACGGGGACGAGGAGTG
TAGGAGCGAGGCAGAGCGCATGGGCTTTCACAACCTAAAGGACGGGGAGGAGCTCACATTCTAG

Upstream 100 bases:

>100_bases
CAAGCCCTCACCTCCGGCAAGCGACGCTTTGAGGCTAAAGGCTGTGGCAACGGGCTTCGGCGGGATATCGCTCGTAGCCG
AGTGCGGCGAACCCTTCGCC

Downstream 100 bases:

>100_bases
CCGGCGCCTCCACCCCCAACAGCCACAGCCCCCTCCTTATCGTGTTCGCCACTGCCTTCACCAAGGCCAACTTTAGGTTT
CTCAGGCCTTCGTCCGGCTC

Product: RNA-metabolising metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MDAGVEPGVDKVILTHAHLDHSLMAPGKEVYATLPTLALAKELWLDAKSLNPDLPWEATDVQKTLNSSFRVPYGRPFKVG
DATVTLFNAGHVLGSAMVLVECEGKRLLYTGDLGTSSFLLDHWSKEVPQADVLVTESSYLCKDRPSAKKEWSRLLYFLKQ
RLREGPVLIAANAVGKVQEVIKFLMNYKEQIGLNAVIVEGMGFRATKIYDEMIEYLKESEVTAWLNGNRRRLTDFVTFPS
SLRERLDMARPGTAVVAPSGSLSGGMSVWWALKGVPYVLLGHVFEPASSLLAGGEVTLKDPLGNEGVVRPPELHLQISRH
ATRQELLQFISLTKAKEVYLVHGDEECRSEAERMGFHNLKDGEELTF

Sequences:

>Translated_367_residues
MDAGVEPGVDKVILTHAHLDHSLMAPGKEVYATLPTLALAKELWLDAKSLNPDLPWEATDVQKTLNSSFRVPYGRPFKVG
DATVTLFNAGHVLGSAMVLVECEGKRLLYTGDLGTSSFLLDHWSKEVPQADVLVTESSYLCKDRPSAKKEWSRLLYFLKQ
RLREGPVLIAANAVGKVQEVIKFLMNYKEQIGLNAVIVEGMGFRATKIYDEMIEYLKESEVTAWLNGNRRRLTDFVTFPS
SLRERLDMARPGTAVVAPSGSLSGGMSVWWALKGVPYVLLGHVFEPASSLLAGGEVTLKDPLGNEGVVRPPELHLQISRH
ATRQELLQFISLTKAKEVYLVHGDEECRSEAERMGFHNLKDGEELTF
>Mature_367_residues
MDAGVEPGVDKVILTHAHLDHSLMAPGKEVYATLPTLALAKELWLDAKSLNPDLPWEATDVQKTLNSSFRVPYGRPFKVG
DATVTLFNAGHVLGSAMVLVECEGKRLLYTGDLGTSSFLLDHWSKEVPQADVLVTESSYLCKDRPSAKKEWSRLLYFLKQ
RLREGPVLIAANAVGKVQEVIKFLMNYKEQIGLNAVIVEGMGFRATKIYDEMIEYLKESEVTAWLNGNRRRLTDFVTFPS
SLRERLDMARPGTAVVAPSGSLSGGMSVWWALKGVPYVLLGHVFEPASSLLAGGEVTLKDPLGNEGVVRPPELHLQISRH
ATRQELLQFISLTKAKEVYLVHGDEECRSEAERMGFHNLKDGEELTF

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI33300633, Length=383, Percent_Identity=24.2819843342037, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7706427, Length=390, Percent_Identity=21.5384615384615, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32564696, Length=374, Percent_Identity=25.1336898395722, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323307, Length=415, Percent_Identity=25.7831325301205, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358523, Length=394, Percent_Identity=26.3959390862944, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 40750; Mature: 40750

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAGVEPGVDKVILTHAHLDHSLMAPGKEVYATLPTLALAKELWLDAKSLNPDLPWEATD
CCCCCCCCCCEEEEEEHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHH
VQKTLNSSFRVPYGRPFKVGDATVTLFNAGHVLGSAMVLVECEGKRLLYTGDLGTSSFLL
HHHHHCCCCCCCCCCCEECCCEEEEEEECCHHHCCEEEEEEECCCEEEEECCCCCHHHHH
DHWSKEVPQADVLVTESSYLCKDRPSAKKEWSRLLYFLKQRLREGPVLIAANAVGKVQEV
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHH
IKFLMNYKEQIGLNAVIVEGMGFRATKIYDEMIEYLKESEVTAWLNGNRRRLTDFVTFPS
HHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCHH
SLRERLDMARPGTAVVAPSGSLSGGMSVWWALKGVPYVLLGHVFEPASSLLAGGEVTLKD
HHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEC
PLGNEGVVRPPELHLQISRHATRQELLQFISLTKAKEVYLVHGDEECRSEAERMGFHNLK
CCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCC
DGEELTF
CCCCCCC
>Mature Secondary Structure
MDAGVEPGVDKVILTHAHLDHSLMAPGKEVYATLPTLALAKELWLDAKSLNPDLPWEATD
CCCCCCCCCCEEEEEEHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHH
VQKTLNSSFRVPYGRPFKVGDATVTLFNAGHVLGSAMVLVECEGKRLLYTGDLGTSSFLL
HHHHHCCCCCCCCCCCEECCCEEEEEEECCHHHCCEEEEEEECCCEEEEECCCCCHHHHH
DHWSKEVPQADVLVTESSYLCKDRPSAKKEWSRLLYFLKQRLREGPVLIAANAVGKVQEV
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHH
IKFLMNYKEQIGLNAVIVEGMGFRATKIYDEMIEYLKESEVTAWLNGNRRRLTDFVTFPS
HHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCHH
SLRERLDMARPGTAVVAPSGSLSGGMSVWWALKGVPYVLLGHVFEPASSLLAGGEVTLKD
HHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEC
PLGNEGVVRPPELHLQISRHATRQELLQFISLTKAKEVYLVHGDEECRSEAERMGFHNLK
CCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCC
DGEELTF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]