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The map label for this gene is sucD2 [H]

Identifier: 156936880

GI number: 156936880

Start: 82186

End: 83076

Strand: Reverse

Name: sucD2 [H]

Synonym: Igni_0085

Alternate gene names: 156936880

Gene position: 83076-82186 (Counterclockwise)

Preceding gene: 156936881

Following gene: 156936879

Centisome position: 6.4

GC content: 60.27

Gene sequence:

>891_bases
GTGGTCGTGTTGGTAGACGAGAACACCCGGGTGGTAGTTCAAGGTATAACCGGGAGGTACGGCAAGTTCCACGCCGAGCA
GATGATGAAGTACGGAACCAAAGTGGTAGCCGGCGTGACGCCGGGGAAGGGAGGACAAGAGGTCTTGGGGGTGCCGGTGT
ACGATACCGTCAAGGAAGCTAAGGAGAACCACCCGGAGATAAACACCTCCATAATCTTCGTTCCGGCCGGAGGGGCGGCC
GACGCCATAATAGAGGCCGCGGACGCGGGGCTGGACCTAATAGTGGTCATAACCGAAGGGATACCGGTTCACGACTCGAT
GAGGGCCATAAGGTACGCGAGGAGCAAAGGCTCCACCGTGGTAGGCCCCAACTGCCCCGGAGTGATAAGCCCGGGCAAGG
CGAAGGTAGGTATAATGCCGGAGAAGTACTTCGTTCCCGGACGGGTAGGAATAGTATCTAGGTCCGGCACGCTGACGTAC
GAGATAGCTTACCAGCTGAGCAAGAGGGGCATAGGCCAGAGCACCGCTATAGGGATCGGCGGGGACCCCATCATAGGCCT
CGATACGGTAGAGGCCGTCAAGCTTATGGATAAGGACCCCGAGACGGACTTAATTGTAGTCATAGGGGAAATAGGGGGAG
ACGCGGAGGAGAGGCTCGCAGCCGCCATAAAGAGGGGAGAGATCGAGAAGCCCGTAGTGGCCTACGTGGCCGGGAGGACC
GCCCCGCCGGGCAAGAGGATGGGTCACGCCGGCGCGATAATAAGCATGGGGGCGGGGACCGCGGAGAGCAAGGTGAGGGC
CTTCCGGGAGGCCGGCGTGCCCGTCGCGGATATACCCAGCCAAGTGCCGGACTTGGTGGTCGAGAAGCTCAAAGAGTTGG
GCAAGCTCTAA

Upstream 100 bases:

>100_bases
TATTGAAGGAGGCCGGCATACCGCTTTTTGAGAGCATGGACGAGGCCGCCCAAGAAGCGGTCAAGCTGGCCAAGGCCGCT
TAAGGGGGAGGTGATGGGAC

Downstream 100 bases:

>100_bases
AGCCCCTTCTGAGGAGACGAATCTATCAAAAGCTCTTTCTTCTACGCCCGCCGGGGCGTGGAGTTGTACAGGATCTACCG
CTTCAAAGACATGGTTAGAA

Product: succinyl-CoA synthetase (ADP-forming) alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 2; SCS-alpha 2 [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MVVLVDENTRVVVQGITGRYGKFHAEQMMKYGTKVVAGVTPGKGGQEVLGVPVYDTVKEAKENHPEINTSIIFVPAGGAA
DAIIEAADAGLDLIVVITEGIPVHDSMRAIRYARSKGSTVVGPNCPGVISPGKAKVGIMPEKYFVPGRVGIVSRSGTLTY
EIAYQLSKRGIGQSTAIGIGGDPIIGLDTVEAVKLMDKDPETDLIVVIGEIGGDAEERLAAAIKRGEIEKPVVAYVAGRT
APPGKRMGHAGAIISMGAGTAESKVRAFREAGVPVADIPSQVPDLVVEKLKELGKL

Sequences:

>Translated_296_residues
MVVLVDENTRVVVQGITGRYGKFHAEQMMKYGTKVVAGVTPGKGGQEVLGVPVYDTVKEAKENHPEINTSIIFVPAGGAA
DAIIEAADAGLDLIVVITEGIPVHDSMRAIRYARSKGSTVVGPNCPGVISPGKAKVGIMPEKYFVPGRVGIVSRSGTLTY
EIAYQLSKRGIGQSTAIGIGGDPIIGLDTVEAVKLMDKDPETDLIVVIGEIGGDAEERLAAAIKRGEIEKPVVAYVAGRT
APPGKRMGHAGAIISMGAGTAESKVRAFREAGVPVADIPSQVPDLVVEKLKELGKL
>Mature_296_residues
MVVLVDENTRVVVQGITGRYGKFHAEQMMKYGTKVVAGVTPGKGGQEVLGVPVYDTVKEAKENHPEINTSIIFVPAGGAA
DAIIEAADAGLDLIVVITEGIPVHDSMRAIRYARSKGSTVVGPNCPGVISPGKAKVGIMPEKYFVPGRVGIVSRSGTLTY
EIAYQLSKRGIGQSTAIGIGGDPIIGLDTVEAVKLMDKDPETDLIVVIGEIGGDAEERLAAAIKRGEIEKPVVAYVAGRT
APPGKRMGHAGAIISMGAGTAESKVRAFREAGVPVADIPSQVPDLVVEKLKELGKL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=49.6598639455782, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI38569423, Length=244, Percent_Identity=34.8360655737705, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI38569421, Length=244, Percent_Identity=34.8360655737705, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1786949, Length=273, Percent_Identity=54.9450549450549, Blast_Score=287, Evalue=5e-79,
Organism=Escherichia coli, GI1786513, Length=224, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786729, Length=223, Percent_Identity=25.5605381165919, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=282, Percent_Identity=51.4184397163121, Blast_Score=263, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17553126, Length=284, Percent_Identity=49.6478873239437, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17557344, Length=287, Percent_Identity=29.616724738676, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17551266, Length=305, Percent_Identity=28.1967213114754, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324716, Length=301, Percent_Identity=43.8538205980066, Blast_Score=219, Evalue=6e-58,
Organism=Drosophila melanogaster, GI21356559, Length=293, Percent_Identity=47.098976109215, Blast_Score=251, Evalue=3e-67,
Organism=Drosophila melanogaster, GI28574296, Length=295, Percent_Identity=48.135593220339, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI281363477, Length=264, Percent_Identity=32.9545454545455, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363475, Length=264, Percent_Identity=32.9545454545455, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363473, Length=264, Percent_Identity=32.9545454545455, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30886; Mature: 30886

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLVDENTRVVVQGITGRYGKFHAEQMMKYGTKVVAGVTPGKGGQEVLGVPVYDTVKEA
CEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHH
KENHPEINTSIIFVPAGGAADAIIEAADAGLDLIVVITEGIPVHDSMRAIRYARSKGSTV
HHCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEE
VGPNCPGVISPGKAKVGIMPEKYFVPGRVGIVSRSGTLTYEIAYQLSKRGIGQSTAIGIG
ECCCCCCCCCCCCEEEECCCCCEECCCCEEEEECCCCEEEEEEEHHHHCCCCCCEEEECC
GDPIIGLDTVEAVKLMDKDPETDLIVVIGEIGGDAEERLAAAIKRGEIEKPVVAYVAGRT
CCCEECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
APPGKRMGHAGAIISMGAGTAESKVRAFREAGVPVADIPSQVPDLVVEKLKELGKL
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVLVDENTRVVVQGITGRYGKFHAEQMMKYGTKVVAGVTPGKGGQEVLGVPVYDTVKEA
CEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHH
KENHPEINTSIIFVPAGGAADAIIEAADAGLDLIVVITEGIPVHDSMRAIRYARSKGSTV
HHCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEE
VGPNCPGVISPGKAKVGIMPEKYFVPGRVGIVSRSGTLTYEIAYQLSKRGIGQSTAIGIG
ECCCCCCCCCCCCEEEECCCCCEECCCCEEEEECCCCEEEEEEEHHHHCCCCCCEEEECC
GDPIIGLDTVEAVKLMDKDPETDLIVVIGEIGGDAEERLAAAIKRGEIEKPVVAYVAGRT
CCCEECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
APPGKRMGHAGAIISMGAGTAESKVRAFREAGVPVADIPSQVPDLVVEKLKELGKL
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]