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The map label for this gene is sucC

Identifier: 156936881

GI number: 156936881

Start: 83094

End: 84224

Strand: Reverse

Name: sucC

Synonym: Igni_0086

Alternate gene names: 156936881

Gene position: 84224-83094 (Counterclockwise)

Preceding gene: 156936887

Following gene: 156936880

Centisome position: 6.49

GC content: 57.12

Gene sequence:

>1131_bases
TTGAACCTCCTCGAGTACGAGGCAAAGGCCATCGCGAAGAAATATGGCATACCGACGCCCGAAGGGGTGCTAATCGAGAG
GCCGGAACAAGTGAACGAAGCAGTGGAGAAGCTCGGACTGCCGGTGGTCTTGAAGGCCCAAGTCCCGGTGGCGGGCAGGG
GGAAGGCCGGAGGGGTTAAGCTTGCCCGCGACCCCGACGAGGCGTTAGAGCTGGCGGAGGAGCTCTTCTCAAAGGAAATA
AAGGGGTTCCCCGTGCTCTCGTTGCTAGTAGAAAAGGCGGAGAACATCCAAAAAGAGTTGTACCTCTCTTTCACAATAGA
CAGAACAAACCGCAAGGTAGTAATGCTGGCCTCCGCCGAGGGCGGGATGGAGATAGAGGAGCTCGCTAAAGAGAAGCCCG
ATGCCATAGTGAAACTCCCCATAGAGCCCGAGGTAGGCCTCAAGGCCCACGAGGCGAGGGAGGTCGGGAAGAGGATAGGC
TTGAGCGGGCAACTGTTAAGGCAGTTCGAGGGGATAGCTAAGACTATGTACAAGATCTTCGAAGATTACGACGCAGAGCT
TGTAGAGAGCAACCCGTTAGCTATAACCGACAGGGGCTTGGTGGCGCTAGACTTCAGGATGATAGTTGACGACAACGCGA
TCTTCAGACACCCGGAGCTCGAGGCCTCTAGGGAGAGGGAGCTGAGCGAGCTGGAGAAGGAGGCCGCCCGCTGGGGCTTC
TTCTACGTCGAGCTGGACGGCGACATAGGGATCATAGGCAACGGGGCCGGACTCACGATGGCCACTATGGACGTCGTCAA
CTATTACGGCGGCAGGCCCGCGAACTTCCTCGACATAGGGGGCGGCGCCAGGAGGGACAGAGTTAAAGCAGCTGTGAACG
TCCTCCTGAAGAATCCAAAGGTAAAGGTAATATTCGTTAACATATTCGGAGGGATAACCTTGGCCAGCGAGGTGGCCCAA
GGAATAGTGGACGCCCTCTCCGAGTCCAACGTCAAGAAGCCCATAGTGGCGAGGATCGTAGGGACCGCGGAGGAGGAGGG
CAAGAAAATATTGAAGGAGGCCGGCATACCGCTTTTTGAGAGCATGGACGAGGCCGCCCAAGAAGCGGTCAAGCTGGCCA
AGGCCGCTTAA

Upstream 100 bases:

>100_bases
ATAGTCGAACGGTTCAATCTGTTCTATTTTCTATTACTTGAGAAATATATATTGCATAAATCAGTTTAATCCGCGCGGTG
AGCCGTAGGAGGGGCGAGCC

Downstream 100 bases:

>100_bases
GGGGGAGGTGATGGGACGTGGTCGTGTTGGTAGACGAGAACACCCGGGTGGTAGTTCAAGGTATAACCGGGAGGTACGGC
AAGTTCCACGCCGAGCAGAT

Product: succinyl-CoA synthetase (ADP-forming) beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNLLEYEAKAIAKKYGIPTPEGVLIERPEQVNEAVEKLGLPVVLKAQVPVAGRGKAGGVKLARDPDEALELAEELFSKEI
KGFPVLSLLVEKAENIQKELYLSFTIDRTNRKVVMLASAEGGMEIEELAKEKPDAIVKLPIEPEVGLKAHEAREVGKRIG
LSGQLLRQFEGIAKTMYKIFEDYDAELVESNPLAITDRGLVALDFRMIVDDNAIFRHPELEASRERELSELEKEAARWGF
FYVELDGDIGIIGNGAGLTMATMDVVNYYGGRPANFLDIGGGARRDRVKAAVNVLLKNPKVKVIFVNIFGGITLASEVAQ
GIVDALSESNVKKPIVARIVGTAEEEGKKILKEAGIPLFESMDEAAQEAVKLAKAA

Sequences:

>Translated_376_residues
MNLLEYEAKAIAKKYGIPTPEGVLIERPEQVNEAVEKLGLPVVLKAQVPVAGRGKAGGVKLARDPDEALELAEELFSKEI
KGFPVLSLLVEKAENIQKELYLSFTIDRTNRKVVMLASAEGGMEIEELAKEKPDAIVKLPIEPEVGLKAHEAREVGKRIG
LSGQLLRQFEGIAKTMYKIFEDYDAELVESNPLAITDRGLVALDFRMIVDDNAIFRHPELEASRERELSELEKEAARWGF
FYVELDGDIGIIGNGAGLTMATMDVVNYYGGRPANFLDIGGGARRDRVKAAVNVLLKNPKVKVIFVNIFGGITLASEVAQ
GIVDALSESNVKKPIVARIVGTAEEEGKKILKEAGIPLFESMDEAAQEAVKLAKAA
>Mature_376_residues
MNLLEYEAKAIAKKYGIPTPEGVLIERPEQVNEAVEKLGLPVVLKAQVPVAGRGKAGGVKLARDPDEALELAEELFSKEI
KGFPVLSLLVEKAENIQKELYLSFTIDRTNRKVVMLASAEGGMEIEELAKEKPDAIVKLPIEPEVGLKAHEAREVGKRIG
LSGQLLRQFEGIAKTMYKIFEDYDAELVESNPLAITDRGLVALDFRMIVDDNAIFRHPELEASRERELSELEKEAARWGF
FYVELDGDIGIIGNGAGLTMATMDVVNYYGGRPANFLDIGGGARRDRVKAAVNVLLKNPKVKVIFVNIFGGITLASEVAQ
GIVDALSESNVKKPIVARIVGTAEEEGKKILKEAGIPLFESMDEAAQEAVKLAKAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=34.4387755102041, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI157779135, Length=380, Percent_Identity=35.7894736842105, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=35.8126721763085, Blast_Score=213, Evalue=3e-55,
Organism=Escherichia coli, GI1786948, Length=382, Percent_Identity=42.9319371727749, Blast_Score=293, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=37.5959079283887, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=34.0153452685422, Blast_Score=221, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=37.8787878787879, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=35.8974358974359, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=37.1501272264631, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=37.1501272264631, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=36.8020304568528, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=36.8020304568528, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_IGNH4 (A8A8L8)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001434677.1
- ProteinModelPortal:   A8A8L8
- SMR:   A8A8L8
- STRING:   A8A8L8
- GeneID:   5562142
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0086
- eggNOG:   arNOG04790
- HOGENOM:   HBG315432
- OMA:   IFINILG
- BioCyc:   IHOS453591:IGNI_0086-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41023; Mature: 41023

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLEYEAKAIAKKYGIPTPEGVLIERPEQVNEAVEKLGLPVVLKAQVPVAGRGKAGGVK
CCCHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEE
LARDPDEALELAEELFSKEIKGFPVLSLLVEKAENIQKELYLSFTIDRTNRKVVMLASAE
ECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEECCC
GGMEIEELAKEKPDAIVKLPIEPEVGLKAHEAREVGKRIGLSGQLLRQFEGIAKTMYKIF
CCCCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EDYDAELVESNPLAITDRGLVALDFRMIVDDNAIFRHPELEASRERELSELEKEAARWGF
HHCCHHHHCCCCEEEECCCEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCEE
FYVELDGDIGIIGNGAGLTMATMDVVNYYGGRPANFLDIGGGARRDRVKAAVNVLLKNPK
EEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCC
VKVIFVNIFGGITLASEVAQGIVDALSESNVKKPIVARIVGTAEEEGKKILKEAGIPLFE
EEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHH
SMDEAAQEAVKLAKAA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLLEYEAKAIAKKYGIPTPEGVLIERPEQVNEAVEKLGLPVVLKAQVPVAGRGKAGGVK
CCCHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEE
LARDPDEALELAEELFSKEIKGFPVLSLLVEKAENIQKELYLSFTIDRTNRKVVMLASAE
ECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEECCC
GGMEIEELAKEKPDAIVKLPIEPEVGLKAHEAREVGKRIGLSGQLLRQFEGIAKTMYKIF
CCCCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EDYDAELVESNPLAITDRGLVALDFRMIVDDNAIFRHPELEASRERELSELEKEAARWGF
HHCCHHHHCCCCEEEECCCEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCEE
FYVELDGDIGIIGNGAGLTMATMDVVNYYGGRPANFLDIGGGARRDRVKAAVNVLLKNPK
EEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCC
VKVIFVNIFGGITLASEVAQGIVDALSESNVKKPIVARIVGTAEEEGKKILKEAGIPLFE
EEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHH
SMDEAAQEAVKLAKAA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA