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The map label for this gene is pyrK [H]

Identifier: 156936837

GI number: 156936837

Start: 40502

End: 41164

Strand: Reverse

Name: pyrK [H]

Synonym: Igni_0042

Alternate gene names: 156936837

Gene position: 41164-40502 (Counterclockwise)

Preceding gene: 156936838

Following gene: 156936833

Centisome position: 3.17

GC content: 57.16

Gene sequence:

>663_bases
ATGAGCTTCAAGGTAGAGGAGGTCTTGAGGAGTCGTAAGCTCGCGAAGGGAATCTACGAAACGTTCGTGAGCTATCATGG
AGAAGCTCCCCCTCCCGGGACGTTCTTCATGGTGTGGGTTCCCGGCCACGAGGCGATTCCCCTTTCGGTGGCGGGCTACC
GCGGCGACGCGGTTCGCTTCATAGTAGAAGTTAGGGGAAGGACCACTGCGGCCCTCTACACGGCCCATAAAGTAGGACTC
CTAGGCCCCCTAGGCCGCCAAGCTCCCGTCCCTTCGGGCAAACCCCTCCTCGTGGGAGGCGGGGTAGGAATAGCTCCCTT
ACTTTACATGAAGGAGCTCTGGGGAGGTGAACTCCTCTTCGGTGCCAAGAGCGCCGAGAAGGTGCCGAAAATCGATGGAA
TAGACGAAGTGGCCACCGAAGACGGGAGTTTGGGGTTCAAGGGTACGGTTGTGGACCTCCTCAAGCTTCGCCCCCAGAAG
AGGGACGTCTACGCTTGTGGCCCACCTTCTATGATTTCGTCACTCAAGGTACTGGCAAAAGAAATGGGGCTGAAGGGCTA
CTACAGTACCGAGAAGATGATAAAGTGTGGAATAGGCATATGCGGGTCGTGTGTCCTAGAGGGTAAGCTGCTCTGCAAGG
AGCCGTGGCTTAGGTTGGGCTGA

Upstream 100 bases:

>100_bases
GGTCGTCTCGAAGAGGCCGCTCAAACTGAAGTGTCACTACTGCGGAGAAATAATAGAAGAGAAAGAGGTCTCTAATTACA
TAAACTTGAGGTGACATAGC

Downstream 100 bases:

>100_bases
GGCCGGGAGACCTCGGACCCATCCGCCCACCAGCGCACAGCGGGCGTAAGGCCCGAGGTACTCGGGAGGTCAGCGAATGG
AGGATTATTAATCTATCCCT

Product: oxidoreductase FAD/NAD(P)-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSFKVEEVLRSRKLAKGIYETFVSYHGEAPPPGTFFMVWVPGHEAIPLSVAGYRGDAVRFIVEVRGRTTAALYTAHKVGL
LGPLGRQAPVPSGKPLLVGGGVGIAPLLYMKELWGGELLFGAKSAEKVPKIDGIDEVATEDGSLGFKGTVVDLLKLRPQK
RDVYACGPPSMISSLKVLAKEMGLKGYYSTEKMIKCGIGICGSCVLEGKLLCKEPWLRLG

Sequences:

>Translated_220_residues
MSFKVEEVLRSRKLAKGIYETFVSYHGEAPPPGTFFMVWVPGHEAIPLSVAGYRGDAVRFIVEVRGRTTAALYTAHKVGL
LGPLGRQAPVPSGKPLLVGGGVGIAPLLYMKELWGGELLFGAKSAEKVPKIDGIDEVATEDGSLGFKGTVVDLLKLRPQK
RDVYACGPPSMISSLKVLAKEMGLKGYYSTEKMIKCGIGICGSCVLEGKLLCKEPWLRLG
>Mature_219_residues
SFKVEEVLRSRKLAKGIYETFVSYHGEAPPPGTFFMVWVPGHEAIPLSVAGYRGDAVRFIVEVRGRTTAALYTAHKVGLL
GPLGRQAPVPSGKPLLVGGGVGIAPLLYMKELWGGELLFGAKSAEKVPKIDGIDEVATEDGSLGFKGTVVDLLKLRPQKR
DVYACGPPSMISSLKVLAKEMGLKGYYSTEKMIKCGIGICGSCVLEGKLLCKEPWLRLG

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 23652; Mature: 23521

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKVEEVLRSRKLAKGIYETFVSYHGEAPPPGTFFMVWVPGHEAIPLSVAGYRGDAVRF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEE
IVEVRGRTTAALYTAHKVGLLGPLGRQAPVPSGKPLLVGGGVGIAPLLYMKELWGGELLF
EEEECCCCEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEE
GAKSAEKVPKIDGIDEVATEDGSLGFKGTVVDLLKLRPQKRDVYACGPPSMISSLKVLAK
CCCCHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
EMGLKGYYSTEKMIKCGIGICGSCVLEGKLLCKEPWLRLG
HHCCCCCCCHHHHHHHCCCHHHHHHHCCEEECCCCCCCCC
>Mature Secondary Structure 
SFKVEEVLRSRKLAKGIYETFVSYHGEAPPPGTFFMVWVPGHEAIPLSVAGYRGDAVRF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEE
IVEVRGRTTAALYTAHKVGLLGPLGRQAPVPSGKPLLVGGGVGIAPLLYMKELWGGELLF
EEEECCCCEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEE
GAKSAEKVPKIDGIDEVATEDGSLGFKGTVVDLLKLRPQKRDVYACGPPSMISSLKVLAK
CCCCHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
EMGLKGYYSTEKMIKCGIGICGSCVLEGKLLCKEPWLRLG
HHCCCCCCCHHHHHHHCCCHHHHHHHCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]