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Identifier: 15679494

GI number: 15679494

Start: 1353166

End: 1354638

Strand: Direct

Name: Not Available

Synonym: MTH1497

Alternate gene names: NA

Gene position: 1353166-1354638 (Clockwise)

Preceding gene: 15679493

Following gene: 15679499

Centisome position: 77.26

GC content: 53.29

Gene sequence:

>1473_bases
GTGTCCCCCATGAGGATTGGACTCGTCTGTATCAGGGGATCGGTCCCTGCCTTTGAGAACTTTGGATTTCTCCCCACCGA
TATAGTTGGAAGCAATGGTCTTGTAAACGGTTCAAGGGCCCACAGGGTCCTGGACGGGATCATAATACCAGGGGGAAGTA
TCGTTGAGTCAGGAAGCCTTTCACCTGAACTTGCATTTGAGATAAGAAGGATGGCATCGGACGGAAAATTTGTCCTGGGT
ATATGCTCAGGATTCCAGGCCCTGGCAGAGAGGACCGATATAGGGAGAAAATCGCCATGCCCTGTTTACAGGGAGGGTCT
CGGGCTCCTCAACGTAACATTCCACCCCATGATAAGCAACGACAGGGTGGAGGCCACCATAACCGGCGAGTCCTTCCTGA
CCTCAGGGATGTCAGGTGAGAGGATAACTGGCTTCCACTGCCATACCTACGGTGAGATACGTGGTGATGCACCTGAGATA
ATGAAGTCCCGCATAGTCAGGGCAGACTATCATGAAAGGCCAGGGGAGATCCTATCAGGGGTCTGCAGTGATGATGGTAA
CGTGGCAGGGACCATGGTCCACGGATGCCTCGATGAGAACCAGACCCTTGTCAGTAACATCCTCAAATTCCTTGATGCGG
ATGAAACTGCAAGGGAGAGGATACTTGAAGCCAACAGGAAACTGCGGGAAGCTCTGAGATCTGAGCTCGGGATATCAACG
GGGATACGTGTTATGGATAGGGGCGGGACGAGGGGCACCCCACCAGCCATAATGATAGCATCCACGGGTTCAGACTCCGG
CAAAACATTCATATTAACGGGCCTTGCAGGCGCCCTGAGGAGGAGGGGCCTCAGGGTGGGCGTTATCAAGGTGGGACCCG
ATGTCAGGGACATAGTCCCGGCCCTCTACCTCATAAAGGAGCCCATGGAGGAGCACTCATCCATAAGGATAGGGCGCCTG
GGCTGGATGGAGCTCAGGGATGTCCTTGAATCTGTGAGGGGAAGATACGACATAATACTCATCGAGGGCGTTATGAGCAT
CCTCACAGGTCTCCTGAACGATATAACACCCTACTCCGGGGCTGAGATTGCCCTGGCAGCAGGTATCCCCCTGATTATGG
TGGCAGGTTGCAGCAAGGGGGGTATAGAGTCTGCGGTGGTTGATCTTGACGCCCACATATCGGTACTTGAGGGACTGGGC
CTTGAGGTCTCCTGCGGAATACTCAACAGGGTCTATGATATGGATATATTTGAGAGGGCATCAGGCGGAAGGTACCTTGC
CATTCCGAGGGTGGAGATGAGTGAGAGGGGCGGCACACCCGAGGTTGAGATAAAACTTGAGGACTTCTGCCTGAAGGCCA
TGGAGACCGTGGAGGAGCACCTTGATGTTGATACCCTCATCAGCTTCGCAAAAAAACCAGAATTCAGGGGTTATATGGGC
CCTGAAGAAATCAAAAAGGTATTCAGTCCCTGA

Upstream 100 bases:

>100_bases
GATGTGGGCGGAGTCCCTGTTGGCCTGCAGCTCCAGGCAAAGCCAGGAGATGATGGCATGATAGTATCGGCCATGAGGGA
GATTGCTTCACTGTAAGAGA

Downstream 100 bases:

>100_bases
ATCCCCGTCTTTGGGATCCCAGCCATCAGGGGCTGGATCCCCTATTTCCGGGAATTAAACCATCAGGTCAGGTTTTAGAT
TCCCATATCCTCTTCAGGGA

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSPMRIGLVCIRGSVPAFENFGFLPTDIVGSNGLVNGSRAHRVLDGIIIPGGSIVESGSLSPELAFEIRRMASDGKFVLG
ICSGFQALAERTDIGRKSPCPVYREGLGLLNVTFHPMISNDRVEATITGESFLTSGMSGERITGFHCHTYGEIRGDAPEI
MKSRIVRADYHERPGEILSGVCSDDGNVAGTMVHGCLDENQTLVSNILKFLDADETARERILEANRKLREALRSELGIST
GIRVMDRGGTRGTPPAIMIASTGSDSGKTFILTGLAGALRRRGLRVGVIKVGPDVRDIVPALYLIKEPMEEHSSIRIGRL
GWMELRDVLESVRGRYDIILIEGVMSILTGLLNDITPYSGAEIALAAGIPLIMVAGCSKGGIESAVVDLDAHISVLEGLG
LEVSCGILNRVYDMDIFERASGGRYLAIPRVEMSERGGTPEVEIKLEDFCLKAMETVEEHLDVDTLISFAKKPEFRGYMG
PEEIKKVFSP

Sequences:

>Translated_490_residues
MSPMRIGLVCIRGSVPAFENFGFLPTDIVGSNGLVNGSRAHRVLDGIIIPGGSIVESGSLSPELAFEIRRMASDGKFVLG
ICSGFQALAERTDIGRKSPCPVYREGLGLLNVTFHPMISNDRVEATITGESFLTSGMSGERITGFHCHTYGEIRGDAPEI
MKSRIVRADYHERPGEILSGVCSDDGNVAGTMVHGCLDENQTLVSNILKFLDADETARERILEANRKLREALRSELGIST
GIRVMDRGGTRGTPPAIMIASTGSDSGKTFILTGLAGALRRRGLRVGVIKVGPDVRDIVPALYLIKEPMEEHSSIRIGRL
GWMELRDVLESVRGRYDIILIEGVMSILTGLLNDITPYSGAEIALAAGIPLIMVAGCSKGGIESAVVDLDAHISVLEGLG
LEVSCGILNRVYDMDIFERASGGRYLAIPRVEMSERGGTPEVEIKLEDFCLKAMETVEEHLDVDTLISFAKKPEFRGYMG
PEEIKKVFSP
>Mature_489_residues
SPMRIGLVCIRGSVPAFENFGFLPTDIVGSNGLVNGSRAHRVLDGIIIPGGSIVESGSLSPELAFEIRRMASDGKFVLGI
CSGFQALAERTDIGRKSPCPVYREGLGLLNVTFHPMISNDRVEATITGESFLTSGMSGERITGFHCHTYGEIRGDAPEIM
KSRIVRADYHERPGEILSGVCSDDGNVAGTMVHGCLDENQTLVSNILKFLDADETARERILEANRKLREALRSELGISTG
IRVMDRGGTRGTPPAIMIASTGSDSGKTFILTGLAGALRRRGLRVGVIKVGPDVRDIVPALYLIKEPMEEHSSIRIGRLG
WMELRDVLESVRGRYDIILIEGVMSILTGLLNDITPYSGAEIALAAGIPLIMVAGCSKGGIESAVVDLDAHISVLEGLGL
EVSCGILNRVYDMDIFERASGGRYLAIPRVEMSERGGTPEVEIKLEDFCLKAMETVEEHLDVDTLISFAKKPEFRGYMGP
EEIKKVFSP

Specific function: Unknown

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017926
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 53024; Mature: 52893

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPMRIGLVCIRGSVPAFENFGFLPTDIVGSNGLVNGSRAHRVLDGIIIPGGSIVESGSL
CCCCEEEEEEEECCCCCHHCCCCCCHHHCCCCCCCCCHHHHHHHCCEEECCCCEECCCCC
SPELAFEIRRMASDGKFVLGICSGFQALAERTDIGRKSPCPVYREGLGLLNVTFHPMISN
CHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEEEEEECC
DRVEATITGESFLTSGMSGERITGFHCHTYGEIRGDAPEIMKSRIVRADYHERPGEILSG
CEEEEEECCHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
VCSDDGNVAGTMVHGCLDENQTLVSNILKFLDADETARERILEANRKLREALRSELGIST
HCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GIRVMDRGGTRGTPPAIMIASTGSDSGKTFILTGLAGALRRRGLRVGVIKVGPDVRDIVP
CCEEEECCCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHCCCEEEEEEECCCHHHHHH
ALYLIKEPMEEHSSIRIGRLGWMELRDVLESVRGRYDIILIEGVMSILTGLLNDITPYSG
HHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCC
AEIALAAGIPLIMVAGCSKGGIESAVVDLDAHISVLEGLGLEVSCGILNRVYDMDIFERA
CCEEEECCCCEEEEECCCCCCCCHHEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHC
SGGRYLAIPRVEMSERGGTPEVEIKLEDFCLKAMETVEEHLDVDTLISFAKKPEFRGYMG
CCCEEEEECCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
PEEIKKVFSP
HHHHHHHHCC
>Mature Secondary Structure 
SPMRIGLVCIRGSVPAFENFGFLPTDIVGSNGLVNGSRAHRVLDGIIIPGGSIVESGSL
CCCEEEEEEEECCCCCHHCCCCCCHHHCCCCCCCCCHHHHHHHCCEEECCCCEECCCCC
SPELAFEIRRMASDGKFVLGICSGFQALAERTDIGRKSPCPVYREGLGLLNVTFHPMISN
CHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEEEEEECC
DRVEATITGESFLTSGMSGERITGFHCHTYGEIRGDAPEIMKSRIVRADYHERPGEILSG
CEEEEEECCHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
VCSDDGNVAGTMVHGCLDENQTLVSNILKFLDADETARERILEANRKLREALRSELGIST
HCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GIRVMDRGGTRGTPPAIMIASTGSDSGKTFILTGLAGALRRRGLRVGVIKVGPDVRDIVP
CCEEEECCCCCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHCCCEEEEEEECCCHHHHHH
ALYLIKEPMEEHSSIRIGRLGWMELRDVLESVRGRYDIILIEGVMSILTGLLNDITPYSG
HHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCC
AEIALAAGIPLIMVAGCSKGGIESAVVDLDAHISVLEGLGLEVSCGILNRVYDMDIFERA
CCEEEECCCCEEEEECCCCCCCCHHEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHC
SGGRYLAIPRVEMSERGGTPEVEIKLEDFCLKAMETVEEHLDVDTLISFAKKPEFRGYMG
CCCEEEEECCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
PEEIKKVFSP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]