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Identifier: 15678475

GI number: 15678475

Start: 385424

End: 386257

Strand: Direct

Name: Not Available

Synonym: MTH447

Alternate gene names: 15678475

Gene position: 385424-386257 (Clockwise)

Preceding gene: 15678474

Following gene: 15678476

Centisome position: 22.01

GC content: 50.84

Gene sequence:

>834_bases
ATGGCAAAAATTCTTGTTGTTGAGGACGAGGCCATAGTGGCCATGGGTATAACCCACAAACTTGAATCAATGGGTCACAG
GGTTGTGGAGACAGTTTCAACAGGTAAGGACGCCATAATGGCGTGCAAGGTCCATGAACCGGACCTCGTTCTCATGGACA
TCGTCCTGAAGGGCGAAATGGATGGTATAGAGGCTGCAAGAAGGATCCGGGACCAGTTCAACATCCCGATAATATACCTG
ACAGCCTATGCCGATGAGGAGATGCTGACACGTGCAAAGGTCACAGAGCCCTACGGGTACATAGTGAAGCCCTTCAAGTC
ATCTGAACTCAATGCCAACATTGAGATGGCCATCTACCGGCACAGATCCGCAATGAGGGAGAAGGAACTCATGAAGAAGC
AGATAATCTCAGACTTCTATAACTTCATCCTCAACGCGATGCCCTCAACCGGAGCCGATGAGGATGCCATCAGGGAACTG
CTATCAGGTATATTCAGGGACAGGATCACACATGAACTCGGCCCCAGATTCAAGGCCCACATGGAGGAGTATCCGGACGA
TGACCTCCTCGAGGCATACCTCGCATGGGTCGCAGACATATTTGAAGGCTTCACTGTGAGGGTGGGTTTCCTTGAGGACG
AAGAGAACGTTTATGTTGAATTTGAGAACTGCCCTTGGCTTGAAGATGCCCGAAAGAACCCCGGCTTCTGCCTGAACTGT
GAGGCCATCCTGAAGTTAAGTTTTGAATGGAGCGAACTCCCCGGTGACTTCAGGGCCATGGGGCAGATTGCAAGGGGAGA
TGACAGGTGCCTCTTCCGGTTTGGTGTTAAGTAA

Upstream 100 bases:

>100_bases
GGCGTCACATTAAACCTTATTCTGCAGTGACATCAAAGTATCAGGGGCAATGTCCAGACATTAGTCCTCAGTGATAGCGG
TTCCATAAAGGAGGTTTATC

Downstream 100 bases:

>100_bases
TTACCGGGTTTCAGTGTTGAGCGTATCAGAGCAAGTATAAAGAGACGTCAGGCTGAAGTTATGATGGTACACGCATGGAT
GATACAATGAGGAGAACAGG

Product: sensory transduction regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MAKILVVEDEAIVAMGITHKLESMGHRVVETVSTGKDAIMACKVHEPDLVLMDIVLKGEMDGIEAARRIRDQFNIPIIYL
TAYADEEMLTRAKVTEPYGYIVKPFKSSELNANIEMAIYRHRSAMREKELMKKQIISDFYNFILNAMPSTGADEDAIREL
LSGIFRDRITHELGPRFKAHMEEYPDDDLLEAYLAWVADIFEGFTVRVGFLEDEENVYVEFENCPWLEDARKNPGFCLNC
EAILKLSFEWSELPGDFRAMGQIARGDDRCLFRFGVK

Sequences:

>Translated_277_residues
MAKILVVEDEAIVAMGITHKLESMGHRVVETVSTGKDAIMACKVHEPDLVLMDIVLKGEMDGIEAARRIRDQFNIPIIYL
TAYADEEMLTRAKVTEPYGYIVKPFKSSELNANIEMAIYRHRSAMREKELMKKQIISDFYNFILNAMPSTGADEDAIREL
LSGIFRDRITHELGPRFKAHMEEYPDDDLLEAYLAWVADIFEGFTVRVGFLEDEENVYVEFENCPWLEDARKNPGFCLNC
EAILKLSFEWSELPGDFRAMGQIARGDDRCLFRFGVK
>Mature_276_residues
AKILVVEDEAIVAMGITHKLESMGHRVVETVSTGKDAIMACKVHEPDLVLMDIVLKGEMDGIEAARRIRDQFNIPIIYLT
AYADEEMLTRAKVTEPYGYIVKPFKSSELNANIEMAIYRHRSAMREKELMKKQIISDFYNFILNAMPSTGADEDAIRELL
SGIFRDRITHELGPRFKAHMEEYPDDDLLEAYLAWVADIFEGFTVRVGFLEDEENVYVEFENCPWLEDARKNPGFCLNCE
AILKLSFEWSELPGDFRAMGQIARGDDRCLFRFGVK

Specific function: Member of the two-component regulatory system pdtaR/pdtaS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=132, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005561
- InterPro:   IPR011006
- InterPro:   IPR008327
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03861 ANTAR; PF00072 Response_reg [H]

EC number: 2.7.3.-

Molecular weight: Translated: 31766; Mature: 31635

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILVVEDEAIVAMGITHKLESMGHRVVETVSTGKDAIMACKVHEPDLVLMDIVLKGEM
CCEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCC
DGIEAARRIRDQFNIPIIYLTAYADEEMLTRAKVTEPYGYIVKPFKSSELNANIEMAIYR
CHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEHH
HRSAMREKELMKKQIISDFYNFILNAMPSTGADEDAIRELLSGIFRDRITHELGPRFKAH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
MEEYPDDDLLEAYLAWVADIFEGFTVRVGFLEDEENVYVEFENCPWLEDARKNPGFCLNC
HHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCHHHHCCCCCEEEEH
EAILKLSFEWSELPGDFRAMGQIARGDDRCLFRFGVK
HHHEEEECCHHHCCCHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure 
AKILVVEDEAIVAMGITHKLESMGHRVVETVSTGKDAIMACKVHEPDLVLMDIVLKGEM
CEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCC
DGIEAARRIRDQFNIPIIYLTAYADEEMLTRAKVTEPYGYIVKPFKSSELNANIEMAIYR
CHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEHH
HRSAMREKELMKKQIISDFYNFILNAMPSTGADEDAIRELLSGIFRDRITHELGPRFKAH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
MEEYPDDDLLEAYLAWVADIFEGFTVRVGFLEDEENVYVEFENCPWLEDARKNPGFCLNC
HHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCHHHHCCCCCEEEEH
EAILKLSFEWSELPGDFRAMGQIARGDDRCLFRFGVK
HHHEEEECCHHHCCCHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]