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Identifier: 15678277

GI number: 15678277

Start: 193221

End: 193814

Strand: Direct

Name: Not Available

Synonym: MTH249

Alternate gene names: 15678277

Gene position: 193221-193814 (Clockwise)

Preceding gene: 15678276

Following gene: 15678278

Centisome position: 11.03

GC content: 50.67

Gene sequence:

>594_bases
TTGATTGAAATGGAGATACTGAGGAATACTGTTCAGAAGATAGCTAAGCACGCCATTGAGGCAATAGATAAGGTCGATGA
AGCTGAACTTGAGATGATGATCTCAAAGATAATGGATGCAAGCTCAGTTTTCATAGTTGGAACCGGCAGGTCCGAGCTGA
TAGGAAAGGCCTTTGCAATGAGGCTTATGCACCTTGGATTCAAGGTCCACGTGGTTGGTGACGTTACAACTCCAGCCATA
AGGGACGAGGACTGCCTGATAGCAATCTCAGGATCCGGTGAAACCAAGACTGTCACACTGGCAGCTGAGACATCAAGGTC
TGTGGGTGCAACGGTGGTGGCTGTGACAGCAACCCCTGAATCGACCCTCACGGGTTACAGTGACGTGGTTATATGCATCC
CGAGCAAGACAAAGGAGCCCTGGAAGTACTACACCTCAGGTGTCCTCAGGGGAGAATATGATGACCTCACACCCATGGGG
ACCCTCTTTGAGGACAGCACCCACCTCTTCCTGGACGGCCTCATAGCCGAGTTCATGTCAATCCTTGGAAAGAGGGAGAA
GGACCTCAAGGAGAGGCACGCCATAATCGAGTAG

Upstream 100 bases:

>100_bases
GGCATAAGGATCACGAACCTTCCAGAGCAAGAGTAATCGCTGCAGTCATCCATGGAAGACCCCTTTAACAGATGCAGCCA
TACACAAGTACTGATTAAAG

Downstream 100 bases:

>100_bases
CTCAACCAGCACTCACGGGAGGTTTGAGAGTGGAGGGACAGCTCGGAGATGAGGTGGTCACCATAAAGGCCACATCCATC
GCAAGGAGGCTTCATGGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIEMEILRNTVQKIAKHAIEAIDKVDEAELEMMISKIMDASSVFIVGTGRSELIGKAFAMRLMHLGFKVHVVGDVTTPAI
RDEDCLIAISGSGETKTVTLAAETSRSVGATVVAVTATPESTLTGYSDVVICIPSKTKEPWKYYTSGVLRGEYDDLTPMG
TLFEDSTHLFLDGLIAEFMSILGKREKDLKERHAIIE

Sequences:

>Translated_197_residues
MIEMEILRNTVQKIAKHAIEAIDKVDEAELEMMISKIMDASSVFIVGTGRSELIGKAFAMRLMHLGFKVHVVGDVTTPAI
RDEDCLIAISGSGETKTVTLAAETSRSVGATVVAVTATPESTLTGYSDVVICIPSKTKEPWKYYTSGVLRGEYDDLTPMG
TLFEDSTHLFLDGLIAEFMSILGKREKDLKERHAIIE
>Mature_197_residues
MIEMEILRNTVQKIAKHAIEAIDKVDEAELEMMISKIMDASSVFIVGTGRSELIGKAFAMRLMHLGFKVHVVGDVTTPAI
RDEDCLIAISGSGETKTVTLAAETSRSVGATVVAVTATPESTLTGYSDVVICIPSKTKEPWKYYTSGVLRGEYDDLTPMG
TLFEDSTHLFLDGLIAEFMSILGKREKDLKERHAIIE

Specific function: Unknown

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788767, Length=105, Percent_Identity=38.0952380952381, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): Y249_METTH (O26351)

Other databases:

- EMBL:   AE000666
- PIR:   B69131
- RefSeq:   NP_275392.1
- ProteinModelPortal:   O26351
- SMR:   O26351
- STRING:   O26351
- GeneID:   1470210
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH249
- NMPDR:   fig|187420.1.peg.247
- eggNOG:   arNOG06880
- HOGENOM:   HBG539462
- OMA:   PMGSAFE
- PhylomeDB:   O26351
- ProtClustDB:   CLSK2750265
- BioCyc:   MTHE187420:MTH249-MONOMER
- InterPro:   IPR017552
- InterPro:   IPR001347
- TIGRFAMs:   TIGR03127

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 21570; Mature: 21570

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS51464 SIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEMEILRNTVQKIAKHAIEAIDKVDEAELEMMISKIMDASSVFIVGTGRSELIGKAFAM
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
RLMHLGFKVHVVGDVTTPAIRDEDCLIAISGSGETKTVTLAAETSRSVGATVVAVTATPE
HHHHCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEEEEECCC
STLTGYSDVVICIPSKTKEPWKYYTSGVLRGEYDDLTPMGTLFEDSTHLFLDGLIAEFMS
HHCCCCCCEEEECCCCCCCCHHHHHCCEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
ILGKREKDLKERHAIIE
HHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MIEMEILRNTVQKIAKHAIEAIDKVDEAELEMMISKIMDASSVFIVGTGRSELIGKAFAM
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
RLMHLGFKVHVVGDVTTPAIRDEDCLIAISGSGETKTVTLAAETSRSVGATVVAVTATPE
HHHHCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEEEEECCC
STLTGYSDVVICIPSKTKEPWKYYTSGVLRGEYDDLTPMGTLFEDSTHLFLDGLIAEFMS
HHCCCCCCEEEECCCCCCCCHHHHHCCEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
ILGKREKDLKERHAIIE
HHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463