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The map label for this gene is gntK

Identifier: 15674166

GI number: 15674166

Start: 2268572

End: 2270131

Strand: Reverse

Name: gntK

Synonym: L52019

Alternate gene names: 15674166

Gene position: 2270131-2268572 (Counterclockwise)

Preceding gene: 15674167

Following gene: 15674165

Centisome position: 95.96

GC content: 39.36

Gene sequence:

>1560_bases
ATGCAATATTTAATAGGCGTCGATTTAGGAACCACAGCAACTAAGGCAGTGCTTTTTGAGAAAAATGGAAAAATAGTTGC
AAGTAGTAGCCAAGCCTATCCCCTCTATCGTGATGCTAGTGGGATGGCAGAAGAATCTCTTGAAGAAATTTTTGAAGCAG
TTTTAGTGACAATCAGGGAAGTTTCAATTAATTTAGAAGATGAAGATGAACTTTTAGCCGTTTCATTTAGTACACAAATG
CACTCGCTAATTGCTTTTGACGAAAATTGGCAGCCACTTACAAGATTAATCACTTGGGCTGATACAAGAGCAGTAAAATA
CACCGAACAAATTAAGGCCTCTAAAAATGGTTTTGATATTTATCGAAGAACCGAAACGCCTCTTCATCCAATGGCTCCTT
TATCTAAATTTATCTGGTTAGAAGCTGAACATCCAGATATTTATCAAAAAGCAGCCCACTATTTGGAACTTAAAGGATAC
ATTTTCCAAAGACTTTTTGGAACAAATAAAATGGATTTATCAACCGCAACAGGTACAGGTATCTTCAATATATTTGAACT
TCATTGGGATAAAGAAGCGCTAGAGTTGACTGGAATCAAAGAAAGTCAATTGCCTAAAGTAGTTGAACCCTATGAGATAG
AAGAAAACCTTCCTCACGAATATGCCAAGAAAATGGGAATTCAAAGCAGCACCAAATTTATTTGGGGTGCAGCCGATGGT
CCGTTGTCAAATTTGGGAGTAAATGCGATTAAACCGGGTGTTGCAGCCATCACAATTGGAACATCTGGTGCGATTCGAGT
AGTTACTGACAAACCTAAAACAGATGAAAAAGGACGCACATTTACCTATGCATTAGACAAAGAGCATTGGGTAGTCGGTG
GTCCCGTAAACTCTGGTGGAGATGTTTTCCGTTGGGCTCGTGACCAAATTTTTGATGGAAAAATTTCTTTTGATGAAGTC
ACGGAACTTGCAGCAAACATTTCCCCGGGCGCTGATGGATTGCTTTTCCACCCCTATCTTGGAGGCGAGCGAGCACCGAT
TTGGGATGCCAATGCCAGAGGTTCATTTTTTGGCCTAAACTACGGACATAATCGTAGTCATATGGCCAGATCTGTTCTTG
AAGGGGTTATCTTCAATATTTATATGGTTGCGCTTAGCCTTGTTGAAGTAGTAGGTGACCTAAATATGATTCAAGCGACA
GGAGGATTTACAAGCTCTGAACTCTGGACACAAATTCTAGCAGATATTTTTGAACAACCAATCAATGTGCCAGAGAGCCG
AGAAGCTGGCTGTTTAGCTGCCATTATTATGGCTGAAAAAGCCCTTGGCTTAATTGAAGATATCAGCGAAATCGAAACGA
TGGTAGGAACAAACGAAACCTACCAACCCAATCCAAAAAATTTCGAAATTTACCGAGAAATTAGTCCAATATTTATCCGA
CTTTCTCGCTCTCTCTTGGCAGAATATGAAAATATTGCCAATTTCCAAAGAAAATTTGAAGAAGAAAACGCAAATTGTAA
AATGAAGTTAGCCACCTTGAGTCAAGCAAAAAACATCTGA

Upstream 100 bases:

>100_bases
GTAAGCTAACTAGGACAAAAAACTTCTGTCAGTAAAAAACTACTGATGATGAAAGAATTTTAAAGTCTGTCAGTAAATAT
ATAGAAGAAAAGGAGCCTAA

Downstream 100 bases:

>100_bases
ATCTCTTATACTAGAAGTTCGACCAAATAGTATAAAAAGGAAATTCAGATGCAAGACTATTCTATCACAAGCCAGAGCAA
AGGGAAACACCTGACCAATC

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MQYLIGVDLGTTATKAVLFEKNGKIVASSSQAYPLYRDASGMAEESLEEIFEAVLVTIREVSINLEDEDELLAVSFSTQM
HSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKNGFDIYRRTETPLHPMAPLSKFIWLEAEHPDIYQKAAHYLELKGY
IFQRLFGTNKMDLSTATGTGIFNIFELHWDKEALELTGIKESQLPKVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDKPKTDEKGRTFTYALDKEHWVVGGPVNSGGDVFRWARDQIFDGKISFDEV
TELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLNYGHNRSHMARSVLEGVIFNIYMVALSLVEVVGDLNMIQAT
GGFTSSELWTQILADIFEQPINVPESREAGCLAAIIMAEKALGLIEDISEIETMVGTNETYQPNPKNFEIYREISPIFIR
LSRSLLAEYENIANFQRKFEEENANCKMKLATLSQAKNI

Sequences:

>Translated_519_residues
MQYLIGVDLGTTATKAVLFEKNGKIVASSSQAYPLYRDASGMAEESLEEIFEAVLVTIREVSINLEDEDELLAVSFSTQM
HSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKNGFDIYRRTETPLHPMAPLSKFIWLEAEHPDIYQKAAHYLELKGY
IFQRLFGTNKMDLSTATGTGIFNIFELHWDKEALELTGIKESQLPKVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDKPKTDEKGRTFTYALDKEHWVVGGPVNSGGDVFRWARDQIFDGKISFDEV
TELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLNYGHNRSHMARSVLEGVIFNIYMVALSLVEVVGDLNMIQAT
GGFTSSELWTQILADIFEQPINVPESREAGCLAAIIMAEKALGLIEDISEIETMVGTNETYQPNPKNFEIYREISPIFIR
LSRSLLAEYENIANFQRKFEEENANCKMKLATLSQAKNI
>Mature_519_residues
MQYLIGVDLGTTATKAVLFEKNGKIVASSSQAYPLYRDASGMAEESLEEIFEAVLVTIREVSINLEDEDELLAVSFSTQM
HSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKNGFDIYRRTETPLHPMAPLSKFIWLEAEHPDIYQKAAHYLELKGY
IFQRLFGTNKMDLSTATGTGIFNIFELHWDKEALELTGIKESQLPKVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDKPKTDEKGRTFTYALDKEHWVVGGPVNSGGDVFRWARDQIFDGKISFDEV
TELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLNYGHNRSHMARSVLEGVIFNIYMVALSLVEVVGDLNMIQAT
GGFTSSELWTQILADIFEQPINVPESREAGCLAAIIMAEKALGLIEDISEIETMVGTNETYQPNPKNFEIYREISPIFIR
LSRSLLAEYENIANFQRKFEEENANCKMKLATLSQAKNI

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=454, Percent_Identity=26.2114537444934, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI4504007, Length=454, Percent_Identity=26.2114537444934, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI189409120, Length=454, Percent_Identity=26.2114537444934, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI41393575, Length=443, Percent_Identity=25.7336343115124, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI88196792, Length=504, Percent_Identity=21.6269841269841, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI164663828, Length=534, Percent_Identity=20.4119850187266, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI164663830, Length=210, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789987, Length=486, Percent_Identity=25.5144032921811, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790005, Length=495, Percent_Identity=25.4545454545455, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1790361, Length=493, Percent_Identity=25.1521298174442, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=24.0556660039761, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789168, Length=453, Percent_Identity=21.8543046357616, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789138, Length=503, Percent_Identity=20.2783300198807, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17535599, Length=469, Percent_Identity=24.7334754797441, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321755, Length=461, Percent_Identity=26.0303687635575, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24656367, Length=498, Percent_Identity=21.8875502008032, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21357867, Length=511, Percent_Identity=21.9178082191781, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17864214, Length=397, Percent_Identity=25.4408060453401, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24654573, Length=397, Percent_Identity=25.4408060453401, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24655555, Length=390, Percent_Identity=24.8717948717949, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655560, Length=390, Percent_Identity=24.8717948717949, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655570, Length=390, Percent_Identity=24.8717948717949, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655574, Length=390, Percent_Identity=24.8717948717949, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655565, Length=390, Percent_Identity=24.8717948717949, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656372, Length=345, Percent_Identity=23.1884057971014, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 57919; Mature: 57919

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYLIGVDLGTTATKAVLFEKNGKIVASSSQAYPLYRDASGMAEESLEEIFEAVLVTIRE
CCEEEEECCCCCHHEEEEEECCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
VSINLEDEDELLAVSFSTQMHSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKNGFDI
HEECCCCCCCEEEEEECHHHHHHEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEE
YRRTETPLHPMAPLSKFIWLEAEHPDIYQKAAHYLELKGYIFQRLFGTNKMDLSTATGTG
EECCCCCCCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
IFNIFELHWDKEALELTGIKESQLPKVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
EEEEEEEECCCHHHEECCCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCC
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDKPKTDEKGRTFTYALDKEHWVVGGPVNSGG
CHHHCCCHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCCC
DVFRWARDQIFDGKISFDEVTELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLN
CHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEECC
YGHNRSHMARSVLEGVIFNIYMVALSLVEVVGDLNMIQATGGFTSSELWTQILADIFEQP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCC
INVPESREAGCLAAIIMAEKALGLIEDISEIETMVGTNETYQPNPKNFEIYREISPIFIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LSRSLLAEYENIANFQRKFEEENANCKMKLATLSQAKNI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCC
>Mature Secondary Structure
MQYLIGVDLGTTATKAVLFEKNGKIVASSSQAYPLYRDASGMAEESLEEIFEAVLVTIRE
CCEEEEECCCCCHHEEEEEECCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
VSINLEDEDELLAVSFSTQMHSLIAFDENWQPLTRLITWADTRAVKYTEQIKASKNGFDI
HEECCCCCCCEEEEEECHHHHHHEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEE
YRRTETPLHPMAPLSKFIWLEAEHPDIYQKAAHYLELKGYIFQRLFGTNKMDLSTATGTG
EECCCCCCCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
IFNIFELHWDKEALELTGIKESQLPKVVEPYEIEENLPHEYAKKMGIQSSTKFIWGAADG
EEEEEEEECCCHHHEECCCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCC
PLSNLGVNAIKPGVAAITIGTSGAIRVVTDKPKTDEKGRTFTYALDKEHWVVGGPVNSGG
CHHHCCCHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCCC
DVFRWARDQIFDGKISFDEVTELAANISPGADGLLFHPYLGGERAPIWDANARGSFFGLN
CHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEECC
YGHNRSHMARSVLEGVIFNIYMVALSLVEVVGDLNMIQATGGFTSSELWTQILADIFEQP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCC
INVPESREAGCLAAIIMAEKALGLIEDISEIETMVGTNETYQPNPKNFEIYREISPIFIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LSRSLLAEYENIANFQRKFEEENANCKMKLATLSQAKNI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]