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The map label for this gene is rnpA

Identifier: 15672110

GI number: 15672110

Start: 131494

End: 131847

Strand: Direct

Name: rnpA

Synonym: L131443

Alternate gene names: 15672110

Gene position: 131494-131847 (Clockwise)

Preceding gene: 15672109

Following gene: 15672111

Centisome position: 5.56

GC content: 33.9

Gene sequence:

>354_bases
TTGGCTATAAAAAAAACATATCGCGTTAAACGCTCAAAGGATTTTGACCAAATTTTTTCAGCGAAACATAGCTTTGCCAA
TAAAAAATTTGTGGTCTATAAATTAAACACAAATCAACCTCATTTTCGTGTAGGTCTATCAGTAAGCAAAAAGCTTGGTC
ATGCGGTTTTACGTAATCGAATTAAACGTCTTTTACGCCATGCCATTGCTGAATTTAAGCCTTATTTGACAGATGAAGAT
TTTGTAATTATTGCACGTTCGGGTGTTGAAACGCTCAGTTTTGAGGAAGTAAAGAAAAATCTAAAACACGTTTTGAAGTT
GTCAAAAATCTATGTGGATGGAGAAAACGATTGA

Upstream 100 bases:

>100_bases
TCCCTTCGTTCTATATAGAACGTTTTCAAGTGATATAGTGACTTTTTAGCAAGTTTATGATAAAATTAATACGATAATTT
CTAAAATGGGAGAGAGTGGC

Downstream 100 bases:

>100_bases
AAAAGAAATTTAGTTTGATCGCAATGGCAGGGGCGGCTCTTTTGTTGCTTACAGCTTGTGGAACAACAGCTGTGACAAGT
AGTTCAACCAACCTTTGGGA

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MAIKKTYRVKRSKDFDQIFSAKHSFANKKFVVYKLNTNQPHFRVGLSVSKKLGHAVLRNRIKRLLRHAIAEFKPYLTDED
FVIIARSGVETLSFEEVKKNLKHVLKLSKIYVDGEND

Sequences:

>Translated_117_residues
MAIKKTYRVKRSKDFDQIFSAKHSFANKKFVVYKLNTNQPHFRVGLSVSKKLGHAVLRNRIKRLLRHAIAEFKPYLTDED
FVIIARSGVETLSFEEVKKNLKHVLKLSKIYVDGEND
>Mature_116_residues
AIKKTYRVKRSKDFDQIFSAKHSFANKKFVVYKLNTNQPHFRVGLSVSKKLGHAVLRNRIKRLLRHAIAEFKPYLTDEDF
VIIARSGVETLSFEEVKKNLKHVLKLSKIYVDGEND

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_LACLA (Q9CJ73)

Other databases:

- EMBL:   AE005176
- PIR:   H86640
- RefSeq:   NP_266284.1
- ProteinModelPortal:   Q9CJ73
- SMR:   Q9CJ73
- GeneID:   1113734
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L131443
- NMPDR:   fig|272623.1.peg.135
- HOGENOM:   HBG728160
- OMA:   KIGNAVM
- ProtClustDB:   PRK00499
- BioCyc:   LLAC272623:L131443-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13648; Mature: 13517

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKTYRVKRSKDFDQIFSAKHSFANKKFVVYKLNTNQPHFRVGLSVSKKLGHAVLRNR
CCCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHH
IKRLLRHAIAEFKPYLTDEDFVIIARSGVETLSFEEVKKNLKHVLKLSKIYVDGEND
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
AIKKTYRVKRSKDFDQIFSAKHSFANKKFVVYKLNTNQPHFRVGLSVSKKLGHAVLRNR
CCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHHHHH
IKRLLRHAIAEFKPYLTDEDFVIIARSGVETLSFEEVKKNLKHVLKLSKIYVDGEND
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471