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The map label for this gene is pyrH [H]

Identifier: 15669445

GI number: 15669445

Start: 1201096

End: 1201818

Strand: Direct

Name: pyrH [H]

Synonym: MJ1259

Alternate gene names: 15669445

Gene position: 1201096-1201818 (Clockwise)

Preceding gene: 15669444

Following gene: 15669446

Centisome position: 72.14

GC content: 34.58

Gene sequence:

>723_bases
TTGATATTAATAACTCTTTTAAAGGATGGGGTTGGTGAGAAGATGAGAATCGTTTTTGATTTGGGAGGTTCAGTCGTGAT
GCCAAAGGAAGGAGCAAAAGCTGAAAAAATTATGGAATATGCCAATATTTTTAAAAAGATTAAGGATGAGGGGCATGAGG
TAGCTATAGTCGTAGGAGGTGGAAAAACAGCAAGAGAATATATAGAAATAGGAAGAGAACTTGGAGCCAGTGAGAGTTTT
TGTGATGAGCTTGGAATAATGGCTACAAGAATGAATGCAATGATATTAATTACTGCTTTAGGAGATTATAGTATAAAAAA
AGTCCCTACATCATTTGAAGAGGCAGAACTTATATTAAACTTAGGAAAAATCCCTGTCATGGGAGGAACCCATCCAGGAC
ATACAACAGACGCTGTAGCTGCTTCATTAGCAGAGTTTATAAATGCTGATTTGTTAGTTATAGGGACAAATGTTGATGGA
GTCTATGACAAAGACCCTAATAAATATGAAGATGCCAAAAAATTTGATAAAATGTCTGCTAAAGAACTTGTTGATTTGGC
AATATCATCTTCATTAAAAGCTGGTTCTTCATCAGTTGTTGATTTATTAGCAGCTAAGATTATTGAAAGAGCTAAATTAA
AAGTGGCAGTTGTTAAAGGAACCCCAGAAGAGCTCTTAAATGTTAGTAAAGGAATAATAAATGGAACAATAATTGAGGGA
TAA

Upstream 100 bases:

>100_bases
AAGATAAATAAGGCACACAATGAACGTCCCAAATAGGGCGTTCAAATATTCATATTTAATTTATACCTTTTGCAAAAAAC
TATAAATAGGGCTATTTTGT

Downstream 100 bases:

>100_bases
GTATGGAGATTCCAAAGCACAGACATTGTTTAAATTGTGGTATCTCAATACCTCCAGACCAAGTTTTTTGTTCAGAGAAG
TGTAGAATTGAGTATATGCA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MILITLLKDGVGEKMRIVFDLGGSVVMPKEGAKAEKIMEYANIFKKIKDEGHEVAIVVGGGKTAREYIEIGRELGASESF
CDELGIMATRMNAMILITALGDYSIKKVPTSFEEAELILNLGKIPVMGGTHPGHTTDAVAASLAEFINADLLVIGTNVDG
VYDKDPNKYEDAKKFDKMSAKELVDLAISSSLKAGSSSVVDLLAAKIIERAKLKVAVVKGTPEELLNVSKGIINGTIIEG

Sequences:

>Translated_240_residues
MILITLLKDGVGEKMRIVFDLGGSVVMPKEGAKAEKIMEYANIFKKIKDEGHEVAIVVGGGKTAREYIEIGRELGASESF
CDELGIMATRMNAMILITALGDYSIKKVPTSFEEAELILNLGKIPVMGGTHPGHTTDAVAASLAEFINADLLVIGTNVDG
VYDKDPNKYEDAKKFDKMSAKELVDLAISSSLKAGSSSVVDLLAAKIIERAKLKVAVVKGTPEELLNVSKGIINGTIIEG
>Mature_240_residues
MILITLLKDGVGEKMRIVFDLGGSVVMPKEGAKAEKIMEYANIFKKIKDEGHEVAIVVGGGKTAREYIEIGRELGASESF
CDELGIMATRMNAMILITALGDYSIKKVPTSFEEAELILNLGKIPVMGGTHPGHTTDAVAASLAEFINADLLVIGTNVDG
VYDKDPNKYEDAKKFDKMSAKELVDLAISSSLKAGSSSVVDLLAAKIIERAKLKVAVVKGTPEELLNVSKGIINGTIIEG

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR001057
- InterPro:   IPR011817
- InterPro:   IPR011818 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25611; Mature: 25611

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILITLLKDGVGEKMRIVFDLGGSVVMPKEGAKAEKIMEYANIFKKIKDEGHEVAIVVGG
CEEEEEECCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
GKTAREYIEIGRELGASESFCDELGIMATRMNAMILITALGDYSIKKVPTSFEEAELILN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCCHHHHHHHHH
LGKIPVMGGTHPGHTTDAVAASLAEFINADLLVIGTNVDGVYDKDPNKYEDAKKFDKMSA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
KELVDLAISSSLKAGSSSVVDLLAAKIIERAKLKVAVVKGTPEELLNVSKGIINGTIIEG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MILITLLKDGVGEKMRIVFDLGGSVVMPKEGAKAEKIMEYANIFKKIKDEGHEVAIVVGG
CEEEEEECCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECC
GKTAREYIEIGRELGASESFCDELGIMATRMNAMILITALGDYSIKKVPTSFEEAELILN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCCCHHHHHHHHH
LGKIPVMGGTHPGHTTDAVAASLAEFINADLLVIGTNVDGVYDKDPNKYEDAKKFDKMSA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
KELVDLAISSSLKAGSSSVVDLLAAKIIERAKLKVAVVKGTPEELLNVSKGIINGTIIEG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]