| Definition | Methanocaldococcus jannaschii DSM 2661 chromosome, complete genome. |
|---|---|
| Accession | NC_000909 |
| Length | 1,664,970 |
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The map label for this gene is top6B [H]
Identifier: 15669217
GI number: 15669217
Start: 959553
End: 961613
Strand: Direct
Name: top6B [H]
Synonym: MJ1028
Alternate gene names: 15669217
Gene position: 959553-961613 (Clockwise)
Preceding gene: 15669216
Following gene: 15669218
Centisome position: 57.63
GC content: 32.27
Gene sequence:
>2061_bases TTGATAAATATAAATATGACAATTTTAAATTTTATATATCATTTTCAACATAAAAGCTTAATTTGCAAAATAAGTTTAAT GGTGGGATTCATGGGAGATGAATTATTTAAAGAATTTAAAGAACATTCAGTTGCTGAATTTTTTAGGAAAAATAAACACA TGCTTGGATACAGTGGAAAAATTAGAAGTTTAACAACTATAATCCATGAATTGGTTACAAACAGCTTAGATGCATGTGAA GAAGCCGGCATTTTGCCAGATATAAAAGTTGAGATTGAGAAGTTAGGAGCTGACCACTATAAAGTGGCAGTTGAAGACAA CGGTCCTGGAATTCCTTTAGAATTCATCCCAAAGGTATTTGGAAAGATGTTAGCTGGTTCTAAGATGCATAGGTTTATTC AATCAAGAGGACAGCAGGGAATTGGGGCTGCTGGAGTTCTGCTATTTTCACAAATAACCACTGGAAAGCCGTTAAAAATT ATAACATCAACTGGAGATGGCAATATCTATGAAGTTGAAGTAAAGATGAATGTTGAGAAAAACGAAGGAGAAATTGTATC AAAAAAAGTAAGAAAAGGAAAATGGAGAGGAACAAGAGTAGAGGGAGAGTTTAAAGAAGTTAGCTACAACAGAGGAGAGT TTGGACCTTTTGAATATTTGAGGAGAATAAGTTTAGCAACACCACACGCAAAAATTGTATTAAAAGACCCTTATGGAGAG GTTGTATTTGATAGGGTTGTTAATGAACTGCCTAAAAAACCAGAGGAGATGAAACCTCATCCTTATGGTTTAACTACCGA TGAACTATTATATATTGCAAGAAAGACAAAATCAAAGAAAGTTTCTTCAATGCTCGTCTCTGAACTTTCAAGAGTTACAA CAAAAAGAATTAAAGAGCTTATAAATTACATGCTTAGAGATTTAATATTAAAGAAATTTAAAGATAGTGTATTTTGGAAC ATGGTTGTTTCTTGCTATTTAAATATAGATATTGAGAGCTATCTAAATAAATTTAAAGATTATATTACCGATGATGAGAT AGAAACCGTTAGAATGTTAATTAAAAACCTTCCAGAGAGCTTAGATGAATTAAAGAGATACGCTTTAAAGTATATAACAA TGGAATATTTATTTAATAAGCTAAGTGAAGAGGAGATAAACAAGTTAAAGAACCACTTTAAGAAGATACCTGAAAACTTT ATGGAATGGGCTGAAAAGAACTATTTATCAGCTACAGTTGTTGATGAATTAAACAAAAAAGTTAAAAATATAGTTAAAAA TCCAGAAGAATTTATCGCTGAAATAAAAAATAAAGGACTAATATCTGATGAAGAACTAAAAAAATTTGAGGATGAAGTCA AAAGCATATTAAATAAAAATCCTAAGGAATTAACTTGGGATGAGGCGGAAATGATTGTTAATTGTCTTCAAAGTATGGAA TTTATGGCTCCTCCAACAACAGGATTAAGACCTATTGGAGCAGAGAATATAGAAAAATCATTAAAAGAGCTTTTACAGCC AGATTTTGTTAAGGCAATTACGAGAAATCCAAAAACTTATAAAGGAGGAATTCCATTCGCTGTTGAAGTTGCTATTGCCT ATGGAGGAAACGCTGGGAGGCAGGGAGACGAAGGAAGAAGAATGGAGATTATGAGATTTGCTAACCACGTTCCTTTGCTG TATGATGCCTCAGCCTGTGGTTTAACTAAGGCAGTTAAGAGTATAAATTGGAAGAGGTATGGGTTGAGAGGAGAAGATGC ACCAATAACAGTGTTTGTTAATCTAATATCTACGTTTATCCCTTACACTTCAGCAGGAAAGCAGGCAGTTGCTTGTAGTG AAAATGAAAATGAAGAAATTTATAATGAAATTAGACATGCGTTGATGATTTGTGGTAGAGAATTAGAGAAATATTTATCA AGAATTAGAAGAGAGGCTGAAGAAGAGAAAAAGAGAAAGTATGTTATGAAGTATGCAAGAATATTTGCTGAGGCATTGGC TAATATATTAAATAAACCAGTTGATGAGATTGAAGAGAAAGTTGTTAAGTTGTTAGAATAA
Upstream 100 bases:
>100_bases CACAGATAGGATGATTGTTGTTAAAGAAAATAAGATTTAAAGTTTAAAAATAGTTTAGTTAATTTCTATTTTGTTACATT ATTTATTTTACTGATATTTA
Downstream 100 bases:
>100_bases ATTTTTATTTTCTTTTCTCTTTTTTAGAATAAATAAAAAGTGAAACAATGTTCAAACCAAAGAAAAAATTAGGGCAATGC TTTTTAATAGATAAGAATTT
Product: DNA topoisomerase VI subunit B
Products: NA
Alternate protein names: Type II DNA topoisomerase VI subunit B; TopoVI-B [H]
Number of amino acids: Translated: 686; Mature: 686
Protein sequence:
>686_residues MININMTILNFIYHFQHKSLICKISLMVGFMGDELFKEFKEHSVAEFFRKNKHMLGYSGKIRSLTTIIHELVTNSLDACE EAGILPDIKVEIEKLGADHYKVAVEDNGPGIPLEFIPKVFGKMLAGSKMHRFIQSRGQQGIGAAGVLLFSQITTGKPLKI ITSTGDGNIYEVEVKMNVEKNEGEIVSKKVRKGKWRGTRVEGEFKEVSYNRGEFGPFEYLRRISLATPHAKIVLKDPYGE VVFDRVVNELPKKPEEMKPHPYGLTTDELLYIARKTKSKKVSSMLVSELSRVTTKRIKELINYMLRDLILKKFKDSVFWN MVVSCYLNIDIESYLNKFKDYITDDEIETVRMLIKNLPESLDELKRYALKYITMEYLFNKLSEEEINKLKNHFKKIPENF MEWAEKNYLSATVVDELNKKVKNIVKNPEEFIAEIKNKGLISDEELKKFEDEVKSILNKNPKELTWDEAEMIVNCLQSME FMAPPTTGLRPIGAENIEKSLKELLQPDFVKAITRNPKTYKGGIPFAVEVAIAYGGNAGRQGDEGRRMEIMRFANHVPLL YDASACGLTKAVKSINWKRYGLRGEDAPITVFVNLISTFIPYTSAGKQAVACSENENEEIYNEIRHALMICGRELEKYLS RIRREAEEEKKRKYVMKYARIFAEALANILNKPVDEIEEKVVKLLE
Sequences:
>Translated_686_residues MININMTILNFIYHFQHKSLICKISLMVGFMGDELFKEFKEHSVAEFFRKNKHMLGYSGKIRSLTTIIHELVTNSLDACE EAGILPDIKVEIEKLGADHYKVAVEDNGPGIPLEFIPKVFGKMLAGSKMHRFIQSRGQQGIGAAGVLLFSQITTGKPLKI ITSTGDGNIYEVEVKMNVEKNEGEIVSKKVRKGKWRGTRVEGEFKEVSYNRGEFGPFEYLRRISLATPHAKIVLKDPYGE VVFDRVVNELPKKPEEMKPHPYGLTTDELLYIARKTKSKKVSSMLVSELSRVTTKRIKELINYMLRDLILKKFKDSVFWN MVVSCYLNIDIESYLNKFKDYITDDEIETVRMLIKNLPESLDELKRYALKYITMEYLFNKLSEEEINKLKNHFKKIPENF MEWAEKNYLSATVVDELNKKVKNIVKNPEEFIAEIKNKGLISDEELKKFEDEVKSILNKNPKELTWDEAEMIVNCLQSME FMAPPTTGLRPIGAENIEKSLKELLQPDFVKAITRNPKTYKGGIPFAVEVAIAYGGNAGRQGDEGRRMEIMRFANHVPLL YDASACGLTKAVKSINWKRYGLRGEDAPITVFVNLISTFIPYTSAGKQAVACSENENEEIYNEIRHALMICGRELEKYLS RIRREAEEEKKRKYVMKYARIFAEALANILNKPVDEIEEKVVKLLE >Mature_686_residues MININMTILNFIYHFQHKSLICKISLMVGFMGDELFKEFKEHSVAEFFRKNKHMLGYSGKIRSLTTIIHELVTNSLDACE EAGILPDIKVEIEKLGADHYKVAVEDNGPGIPLEFIPKVFGKMLAGSKMHRFIQSRGQQGIGAAGVLLFSQITTGKPLKI ITSTGDGNIYEVEVKMNVEKNEGEIVSKKVRKGKWRGTRVEGEFKEVSYNRGEFGPFEYLRRISLATPHAKIVLKDPYGE VVFDRVVNELPKKPEEMKPHPYGLTTDELLYIARKTKSKKVSSMLVSELSRVTTKRIKELINYMLRDLILKKFKDSVFWN MVVSCYLNIDIESYLNKFKDYITDDEIETVRMLIKNLPESLDELKRYALKYITMEYLFNKLSEEEINKLKNHFKKIPENF MEWAEKNYLSATVVDELNKKVKNIVKNPEEFIAEIKNKGLISDEELKKFEDEVKSILNKNPKELTWDEAEMIVNCLQSME FMAPPTTGLRPIGAENIEKSLKELLQPDFVKAITRNPKTYKGGIPFAVEVAIAYGGNAGRQGDEGRRMEIMRFANHVPLL YDASACGLTKAVKSINWKRYGLRGEDAPITVFVNLISTFIPYTSAGKQAVACSENENEEIYNEIRHALMICGRELEKYLS RIRREAEEEKKRKYVMKYARIFAEALANILNKPVDEIEEKVVKLLE
Specific function: Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP [H]
COG id: COG1389
COG function: function code L; DNA topoisomerase VI, subunit B
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TOP6B family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR005734 - InterPro: IPR015320 - ProDom: PD013790 [H]
Pfam domain/function: PF02518 HATPase_c; PF09239 Topo-VIb_trans [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 78793; Mature: 78793
Theoretical pI: Translated: 8.78; Mature: 8.78
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MININMTILNFIYHFQHKSLICKISLMVGFMGDELFKEFKEHSVAEFFRKNKHMLGYSGK CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH IRSLTTIIHELVTNSLDACEEAGILPDIKVEIEKLGADHYKVAVEDNGPGIPLEFIPKVF HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHH GKMLAGSKMHRFIQSRGQQGIGAAGVLLFSQITTGKPLKIITSTGDGNIYEVEVKMNVEK HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEECCC NEGEIVSKKVRKGKWRGTRVEGEFKEVSYNRGEFGPFEYLRRISLATPHAKIVLKDPYGE CCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHH VVFDRVVNELPKKPEEMKPHPYGLTTDELLYIARKTKSKKVSSMLVSELSRVTTKRIKEL HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH INYMLRDLILKKFKDSVFWNMVVSCYLNIDIESYLNKFKDYITDDEIETVRMLIKNLPES HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH LDELKRYALKYITMEYLFNKLSEEEINKLKNHFKKIPENFMEWAEKNYLSATVVDELNKK HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH VKNIVKNPEEFIAEIKNKGLISDEELKKFEDEVKSILNKNPKELTWDEAEMIVNCLQSME HHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH FMAPPTTGLRPIGAENIEKSLKELLQPDFVKAITRNPKTYKGGIPFAVEVAIAYGGNAGR HCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCC QGDEGRRMEIMRFANHVPLLYDASACGLTKAVKSINWKRYGLRGEDAPITVFVNLISTFI CCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC PYTSAGKQAVACSENENEEIYNEIRHALMICGRELEKYLSRIRREAEEEKKRKYVMKYAR CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IFAEALANILNKPVDEIEEKVVKLLE HHHHHHHHHHCCCHHHHHHHHHHHHC >Mature Secondary Structure MININMTILNFIYHFQHKSLICKISLMVGFMGDELFKEFKEHSVAEFFRKNKHMLGYSGK CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH IRSLTTIIHELVTNSLDACEEAGILPDIKVEIEKLGADHYKVAVEDNGPGIPLEFIPKVF HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHH GKMLAGSKMHRFIQSRGQQGIGAAGVLLFSQITTGKPLKIITSTGDGNIYEVEVKMNVEK HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEEECCC NEGEIVSKKVRKGKWRGTRVEGEFKEVSYNRGEFGPFEYLRRISLATPHAKIVLKDPYGE CCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHH VVFDRVVNELPKKPEEMKPHPYGLTTDELLYIARKTKSKKVSSMLVSELSRVTTKRIKEL HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH INYMLRDLILKKFKDSVFWNMVVSCYLNIDIESYLNKFKDYITDDEIETVRMLIKNLPES HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH LDELKRYALKYITMEYLFNKLSEEEINKLKNHFKKIPENFMEWAEKNYLSATVVDELNKK HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH VKNIVKNPEEFIAEIKNKGLISDEELKKFEDEVKSILNKNPKELTWDEAEMIVNCLQSME HHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH FMAPPTTGLRPIGAENIEKSLKELLQPDFVKAITRNPKTYKGGIPFAVEVAIAYGGNAGR HCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCC QGDEGRRMEIMRFANHVPLLYDASACGLTKAVKSINWKRYGLRGEDAPITVFVNLISTFI CCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC PYTSAGKQAVACSENENEEIYNEIRHALMICGRELEKYLSRIRREAEEEKKRKYVMKYAR CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IFAEALANILNKPVDEIEEKVVKLLE HHHHHHHHHHCCCHHHHHHHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]