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The map label for this gene is cbiC

Identifier: 15669120

GI number: 15669120

Start: 860301

End: 860933

Strand: Direct

Name: cbiC

Synonym: MJ0930

Alternate gene names: 15669120

Gene position: 860301-860933 (Clockwise)

Preceding gene: 15669119

Following gene: 15669121

Centisome position: 51.67

GC content: 32.7

Gene sequence:

>633_bases
ATGGGAGCAATATCAAAAGATGGATTAAATATAGCAAATAAATCAAGGGAAATCGTTAGAAATAAAATAAAAGAGGTTTT
AGGAGACAGAATAAATGAATTCAACGAAAAAGAAATGGGAATTATTGAAAGAGTAGTTCATGCTACAGCAGACCCTGAGT
ATGCCAAACTTTTAGTGTTTAAAAATAACCCAATAGAGGAAGGAATTAAAGCTATAAAGGAAGAAAAACCAATAATAGTT
GATGTAAATATGATTAAAGCTGGGATTAGATATAATAAAGTACATTGTTTTATAAATCATCCAGATGTCTATGAAGTTGC
TAAAAAAGAGGGGATAACAAGAGCAGTAGCTTCAATGAGATTGGCTAAGGATTTGATAGATGATGGAATTGTAGTTATCG
GAAACTCCCCAACTGCATTGTTTGAGGTTATAAGATTAGTTAAAGAAGAAAATATAAAACCAAAATTAATTGTTGGAGTT
CCAGTGGGGTTTGTTCAGGCATCAGAATCAAAAGAAGCACTTAGAGAGGTAAATGTTCCAAGTATATCAACCATAGGCCC
AAAAGGAGGAACTCCAGTAGCTGTTGCCATAATTAACGGCATTATTGCCTATGCAAAAAATGAAAAAGCTTAA

Upstream 100 bases:

>100_bases
TAAAACTCTAAAGAATAAAAAGTACTAAAAATAATGGCTTATCCTATTTTTTCTATTTTTAACTTCTATATTTTCAGTTT
TGGTGATTTTTATGGATTTT

Downstream 100 bases:

>100_bases
GGTGAGTAAAATGGAAATATTAGTTAGATATGGAGAAATTGGATTAAAATCAGACCCAATTAGAAAAAACTTAGAGGAAA
TCTTAAGAAAAAACATTATA

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MGAISKDGLNIANKSREIVRNKIKEVLGDRINEFNEKEMGIIERVVHATADPEYAKLLVFKNNPIEEGIKAIKEEKPIIV
DVNMIKAGIRYNKVHCFINHPDVYEVAKKEGITRAVASMRLAKDLIDDGIVVIGNSPTALFEVIRLVKEENIKPKLIVGV
PVGFVQASESKEALREVNVPSISTIGPKGGTPVAVAIINGIIAYAKNEKA

Sequences:

>Translated_210_residues
MGAISKDGLNIANKSREIVRNKIKEVLGDRINEFNEKEMGIIERVVHATADPEYAKLLVFKNNPIEEGIKAIKEEKPIIV
DVNMIKAGIRYNKVHCFINHPDVYEVAKKEGITRAVASMRLAKDLIDDGIVVIGNSPTALFEVIRLVKEENIKPKLIVGV
PVGFVQASESKEALREVNVPSISTIGPKGGTPVAVAIINGIIAYAKNEKA
>Mature_209_residues
GAISKDGLNIANKSREIVRNKIKEVLGDRINEFNEKEMGIIERVVHATADPEYAKLLVFKNNPIEEGIKAIKEEKPIIVD
VNMIKAGIRYNKVHCFINHPDVYEVAKKEGITRAVASMRLAKDLIDDGIVVIGNSPTALFEVIRLVKEENIKPKLIVGVP
VGFVQASESKEALREVNVPSISTIGPKGGTPVAVAIINGIIAYAKNEKA

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIC_METJA (Q58340)

Other databases:

- EMBL:   L77117
- PIR:   B64416
- RefSeq:   NP_247925.1
- ProteinModelPortal:   Q58340
- SMR:   Q58340
- GeneID:   1451819
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0930
- NMPDR:   fig|243232.1.peg.962
- TIGR:   MJ0930
- HOGENOM:   HBG553498
- OMA:   KAGIRYN
- ProtClustDB:   PRK06264
- BioCyc:   MJAN243232:MJ_0930-MONOMER
- InterPro:   IPR003722
- Gene3D:   G3DSA:3.40.50.10230

Pfam domain/function: PF02570 CbiC; SSF63965 CbiC

EC number: 5.4.1.2

Molecular weight: Translated: 22974; Mature: 22843

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: ACT_SITE 47-47

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAISKDGLNIANKSREIVRNKIKEVLGDRINEFNEKEMGIIERVVHATADPEYAKLLVF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEE
KNNPIEEGIKAIKEEKPIIVDVNMIKAGIRYNKVHCFINHPDVYEVAKKEGITRAVASMR
CCCCHHHHHHHHHHCCCEEEEHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LAKDLIDDGIVVIGNSPTALFEVIRLVKEENIKPKLIVGVPVGFVQASESKEALREVNVP
HHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCHHHHHHHHCCCC
SISTIGPKGGTPVAVAIINGIIAYAKNEKA
CCEECCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GAISKDGLNIANKSREIVRNKIKEVLGDRINEFNEKEMGIIERVVHATADPEYAKLLVF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEE
KNNPIEEGIKAIKEEKPIIVDVNMIKAGIRYNKVHCFINHPDVYEVAKKEGITRAVASMR
CCCCHHHHHHHHHHCCCEEEEHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LAKDLIDDGIVVIGNSPTALFEVIRLVKEENIKPKLIVGVPVGFVQASESKEALREVNVP
HHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCHHHHHHHHCCCC
SISTIGPKGGTPVAVAIINGIIAYAKNEKA
CCEECCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087